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Wyszukujesz frazę ""Anti-Bacterial Agents"" wg kryterium: Temat


Tytuł :
Synthesis, Antibacterial and Pharmacokinetic Evaluation of Novel Derivatives of Harmine N -Cinnamic Acid.
Autorzy :
Liang Y; School of Pharmacy, Lanzhou University, West Donggang Road No. 199, Lanzhou 730000, China.
He D; School of Pharmacy, Lanzhou University, West Donggang Road No. 199, Lanzhou 730000, China.
Zhou D; Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Qilihe District, Lanzhou 730050, China.
Li J; Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Qilihe District, Lanzhou 730050, China.
Tang L; Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of Chinese Academy of Agriculture Sciences, No. 335, Qilihe District, Lanzhou 730050, China.
Wang Z; School of Pharmacy, Lanzhou University, West Donggang Road No. 199, Lanzhou 730000, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 10; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 10.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*chemical synthesis
Anti-Bacterial Agents/*pharmacokinetics
Cinnamates/*chemical synthesis
Cinnamates/*pharmacokinetics
Animals ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/chemistry ; Cell Death/drug effects ; Cell Line, Tumor ; Cinnamates/administration & dosage ; Cinnamates/chemistry ; Female ; Humans ; Injections, Intravenous ; Male ; Microbial Sensitivity Tests ; Molecular Conformation ; Rats, Sprague-Dawley ; Time Factors
Czasopismo naukowe
Tytuł :
Biomarker-Guided Individualization of Antibiotic Therapy.
Autorzy :
Aulin LBS; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
de Lange DW; Department of Intensive Care Medicine, University Medical Center, University Utrecht, Utrecht, The Netherlands.
Saleh MAA; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
van der Graaf PH; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Certara, Canterbury, UK.
Völler S; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Pharmacy, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
van Hasselt JGC; Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Aug; Vol. 110 (2), pp. 346-360. Date of Electronic Publication: 2021 Mar 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Anti-Bacterial Agents/*pharmacokinetics
Anti-Bacterial Agents/*therapeutic use
Bacterial Infections/*drug therapy
Drug Monitoring/*methods
Inflammation Mediators/*blood
Age Factors ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/adverse effects ; Biomarkers ; C-Reactive Protein/analysis ; Healthy Volunteers ; Humans ; Interleukin-6/blood ; Lipopolysaccharide Receptors/blood ; Lipopolysaccharides/pharmacology ; Metabolic Clearance Rate ; Models, Biological ; Peptide Fragments/blood ; Procalcitonin/blood
Czasopismo naukowe
Tytuł :
Chemical "Butterfly Effect" Explaining the Coordination Chemistry and Antimicrobial Properties of Clavanin Complexes.
Autorzy :
Miller A; Faculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Matera-Witkiewicz A; Screening Laboratory of Biological Activity Tests and Collection of Biological Material, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
Mikołajczyk A; Screening Laboratory of Biological Activity Tests and Collection of Biological Material, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
Wieczorek R; Faculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
Rowińska-Żyrek M; Faculty of Chemistry, University of Wroclaw, F. Joliot-Curie 14, 50-383 Wroclaw, Poland.
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Źródło :
Inorganic chemistry [Inorg Chem] 2021 Sep 06; Vol. 60 (17), pp. 12730-12734. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Blood Proteins/*pharmacology
Coordination Complexes/*pharmacology
Amino Acid Sequence ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/toxicity ; Bacteria/drug effects ; Blood Proteins/chemistry ; Blood Proteins/toxicity ; Candida albicans/drug effects ; Cell Line ; Coordination Complexes/chemistry ; Coordination Complexes/toxicity ; Copper/chemistry ; Humans ; Microbial Sensitivity Tests ; Zinc/chemistry
Czasopismo naukowe
Tytuł :
Ceftriaxone and methicillin-susceptible staphylococcus aureus : a perspective from pharmacokinetics/pharmacodynamics studies.
Autorzy :
Telles JP; Department of Infectious Diseases, AC Camargo Cancer Center, São Paulo, SP, Brazil.; Department of Infectious Diseases, Hospital Universitário Evangélico Mackenzie, Curitiba, PR, Brazil.
Leme RCP; Department of Infectious Diseases, Hospital Unimed Volta Redonda, Volta Redonda, RJ, Brazil.
Campos ML; Federal University of Mato Grosso, Health Sciences Institute, Sinop, Mato Grosso, Brazil.
Ito C; Division of Microbiology, Universidade Estadual De Ponta Grossa, Ponta Grossa, PR, Brazil.; Laboratory of Emerging Infectious Diseases, Pontifícia Universidade Católica Do Paraná, Curitiba, PR, Brazil.
Bail L; Laboratory of Emerging Infectious Diseases, Pontifícia Universidade Católica Do Paraná, Curitiba, PR, Brazil.
Nogueira KDS; Hospital De Clínicas, Universidade Federal Do Paraná, Curitiba, PR, Brazil.; Basic Pathology Department, Universidade Federal Do Paraná, Curitiba, PR, Brazil.
Tuon FF; Department of Infectious Diseases, Hospital Universitário Evangélico Mackenzie, Curitiba, PR, Brazil.; Laboratory of Emerging Infectious Diseases, Pontifícia Universidade Católica Do Paraná, Curitiba, PR, Brazil.
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Źródło :
Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2021 Sep; Vol. 17 (9), pp. 1039-1048. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Bacterial Agents/*administration & dosage
Ceftriaxone/*administration & dosage
Staphylococcal Infections/*drug therapy
Staphylococcus aureus/*drug effects
Anti-Bacterial Agents/pharmacokinetics ; Anti-Bacterial Agents/pharmacology ; Ceftriaxone/pharmacokinetics ; Ceftriaxone/pharmacology ; Drug Administration Schedule ; Drug Resistance, Bacterial ; Humans ; Methicillin/pharmacology ; Microbial Sensitivity Tests ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/isolation & purification
Czasopismo naukowe
Tytuł :
Antimicrobial resistance trends of non-fermenter Gram negative bacteria in Saudi Arabia: A six-year national study.
Autorzy :
Somily A; Department of Pathology and Laboratory Medicine/Microbiology, College of Medicine, King Saud University, King Saud University Medical City, Riyadh 11461, Saudi Arabia. Electronic address: .
Balkhy HH; World Health Organization, Geneva 1211, Switzerland.
Enani MAS; Medical Specialties Department and Infectious Diseases Section, King Fahad Medical City, Riyadh, 12231, Saudi Arabia.
Althawadi SI; Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, 11211, Saudi Arabia.
Alawi M; Infection Control & Environmental Health Unit, Department of Medical Microbiology & Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Al Johani SM; Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, 11211, Saudi Arabia.
Al Jindan R; Department of Microbiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
AlBarrak A; Department of Internal Medicine, Infectious Diseases Unit, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
AlAjlan H; Prince Sultan Military Medical City, Saudi Arabia.
AlAgeel AA; Microbiology Department, King Fahad Medical City, Ministry of Health, Riyadh, Saudi Arabia.
Roushdy HM; Medical Microbiology, General Directorate of Infection Prevention and Control, Ministry of Health, Saudi Arabia.
Dada HM; National Antimicrobial Resistance Department, Public Health Authority, Riyadh, Saudi Arabia.
Al-Abdely HM; Internal Medicine Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
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Źródło :
Journal of infection and public health [J Infect Public Health] 2021 Sep; Vol. 14 (9), pp. 1144-1150. Date of Electronic Publication: 2021 Jul 15.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Anti-Bacterial Agents*/pharmacology
Anti-Bacterial Agents*/therapeutic use
Drug Resistance, Bacterial*
Gram-Negative Bacteria ; Humans ; Microbial Sensitivity Tests ; Retrospective Studies ; Saudi Arabia/epidemiology
Czasopismo naukowe
Tytuł :
The influence of chest X-ray results on antibiotic prescription for childhood pneumonia in the emergency department.
Autorzy :
van de Maat JS; Department of General Paediatrics, Erasmus MC - Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands.
Garcia Perez D; Department of General Paediatrics, Erasmus MC - Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands.
Driessen GJA; Department of Paediatrics, HAGA-Juliana Children's Hospital, Den Haag, The Netherlands.
van Wermeskerken AM; Department of Paediatrics, Flevoziekenhuis, Almere, The Netherlands.
Smit FJ; Department of Paediatrics, Maasstad Ziekenhuis, Rotterdam, The Netherlands.
Noordzij JG; Department of Paediatrics, Reinier de Graaf Gasthuis, Delft, The Netherlands.
Tramper-Stranders G; Department of Paediatrics, Franciscus Gasthuis &Vlietland, locatie Gasthuis, Rotterdam, The Netherlands.
Obihara CC; Department of Paediatrics, Elisabeth Tweestedenziekenhuis, Tilburg, The Netherlands.
Punt J; Department of Paediatrics, Langeland Ziekenhuis, Zoetermeer, The Netherlands.
Moll HA; Department of General Paediatrics, Erasmus MC - Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands.
Oostenbrink R; Department of General Paediatrics, Erasmus MC - Sophia Children's Hospital, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands. .
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Źródło :
European journal of pediatrics [Eur J Pediatr] 2021 Sep; Vol. 180 (9), pp. 2765-2772. Date of Electronic Publication: 2021 Mar 22.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Anti-Bacterial Agents*/therapeutic use
Pneumonia*/diagnostic imaging
Pneumonia*/drug therapy
Child, Preschool ; Drug Prescriptions ; Emergency Service, Hospital ; Female ; Humans ; Infant ; Male ; X-Rays
Czasopismo naukowe
Tytuł :
From Unimolecular Template to Silver Nanocrystal Clusters: An Effective Strategy to Balance Antibacterial Activity and Cytotoxicity.
Autorzy :
Lin F; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Qi Q; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Zhang J; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Zhou W; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Zhang J; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Fu P; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Zhang X; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Qiao X; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Liu M; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Pang X; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Cui Z; School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
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Źródło :
ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2021 Aug 25; Vol. 13 (33), pp. 39806-39818. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*adverse effects
Anti-Bacterial Agents/*chemistry
Metal Nanoparticles/*chemistry
Silver/*chemistry
Anti-Bacterial Agents/metabolism ; Borohydrides/chemistry ; Cell Survival/drug effects ; Escherichia coli/drug effects ; Humans ; Microbial Sensitivity Tests ; Particle Size ; Polymers/chemistry ; Quaternary Ammonium Compounds/chemistry ; Staphylococcus aureus/drug effects ; Surface Properties ; Theranostic Nanomedicine
Czasopismo naukowe
Tytuł :
Functional Hyaluronic Acid-Polylactic Acid/Silver Nanoparticles Core-Sheath Nanofiber Membranes for Prevention of Post-Operative Tendon Adhesion.
Autorzy :
Chen CH; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital at Keelung, Keelung 20401, Taiwan.; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital at Linkou, Collage of Medicine, Chang Gung University, Kwei-San, Taoyuan 33305, Taiwan.
Cheng YH; Department of Chemical and Materials Engineering, Chang Gung University, Kwei-San, Taoyuan 33302, Taiwan.
Chen SH; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital at Linkou, Collage of Medicine, Chang Gung University, Kwei-San, Taoyuan 33305, Taiwan.
Chuang AD; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital at Keelung, Keelung 20401, Taiwan.
Chen JP; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital at Linkou, Collage of Medicine, Chang Gung University, Kwei-San, Taoyuan 33305, Taiwan.; Department of Chemical and Materials Engineering, Chang Gung University, Kwei-San, Taoyuan 33302, Taiwan.; Research Center for Food and Cosmetic Safety, Research Center for Chinese Herbal Medicine, Linkou Campus, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 33305, Taiwan.; Department of Materials Engineering, Ming Chi University of Technology, Tai-Shan, New Taipei City 24301, Taiwan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 16; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*administration & dosage
Hyaluronic Acid/*administration & dosage
Polyesters/*chemistry
Silver/*chemistry
Tendon Injuries/*drug therapy
3T3 Cells ; Animals ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Disease Models, Animal ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Hyaluronic Acid/chemistry ; Hyaluronic Acid/pharmacology ; Metal Nanoparticles ; Mice ; Microbial Sensitivity Tests ; Nanofibers/chemistry ; Photoelectron Spectroscopy ; Rabbits ; Tendon Injuries/surgery ; Tissue Adhesions/prevention & control
Czasopismo naukowe
Tytuł :
Interest of Homodialkyl Neamine Derivatives against Resistant P. aeruginosa , E. coli , and β-Lactamases-Producing Bacteria-Effect of Alkyl Chain Length on the Interaction with LPS.
Autorzy :
Swain J; Université Catholique de Louvain, Louvain Drug Research Institute, Pharmacologie Cellulaire et Moléculaire, Avenue E. Mounier 73, UCL B1.73.05, 1200 Brussels, Belgium.
Dezanet C; Université Grenoble Alpes, CNRS, Département de Pharmacochimie Moléculaire, Rue de la Chimie, F-38041 Grenoble, France.
Chalhoub H; Université Catholique de Louvain, Louvain Drug Research Institute, Pharmacologie Cellulaire et Moléculaire, Avenue E. Mounier 73, UCL B1.73.05, 1200 Brussels, Belgium.
Auquière M; Université Catholique de Louvain, Louvain Drug Research Institute, Pharmacologie Cellulaire et Moléculaire, Avenue E. Mounier 73, UCL B1.73.05, 1200 Brussels, Belgium.
Kempf J; Université Grenoble Alpes, CNRS, Département de Pharmacochimie Moléculaire, Rue de la Chimie, F-38041 Grenoble, France.
Décout JL; Université Grenoble Alpes, CNRS, Département de Pharmacochimie Moléculaire, Rue de la Chimie, F-38041 Grenoble, France.
Mingeot-Leclercq MP; Université Catholique de Louvain, Louvain Drug Research Institute, Pharmacologie Cellulaire et Moléculaire, Avenue E. Mounier 73, UCL B1.73.05, 1200 Brussels, Belgium.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 13; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Allyl Compounds/*pharmacology
Anti-Bacterial Agents/*pharmacology
Framycetin/*chemistry
Gram-Negative Bacteria/*growth & development
Lipopolysaccharides/*metabolism
Allyl Compounds/chemical synthesis ; Allyl Compounds/chemistry ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Cell Membrane Permeability/drug effects ; Drug Resistance, Bacterial/drug effects ; Escherichia coli/drug effects ; Escherichia coli/growth & development ; Escherichia coli/metabolism ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacteria/metabolism ; Microbial Sensitivity Tests ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/growth & development ; Pseudomonas aeruginosa/metabolism
Czasopismo naukowe
Tytuł :
Antibacterial Polysiloxane Polymers and Coatings for Cochlear Implants.
Autorzy :
Cozma V; Department of Otorhinolaryngology, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Rosca I; Centre of Advanced Research in Bionanoconjugates and Biopolymers, 'Petru Poni' Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.
Radulescu L; Department of Otorhinolaryngology, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Martu C; Department of Otorhinolaryngology, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Nastasa V; Laboratory of Antimicrobial Chemotherapy, Faculty of Veterinary Medicine, 'Ion Ionescu de la Brad' University of Life Sciences, 8 Sadoveanu Alley, 700489 Iasi, Romania.
Varganici CD; Centre of Advanced Research in Bionanoconjugates and Biopolymers, 'Petru Poni' Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.
Ursu EL; Centre of Advanced Research in Bionanoconjugates and Biopolymers, 'Petru Poni' Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.
Doroftei F; Centre of Advanced Research in Bionanoconjugates and Biopolymers, 'Petru Poni' Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.
Pinteala M; Centre of Advanced Research in Bionanoconjugates and Biopolymers, 'Petru Poni' Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.
Racles C; Department of Inorganic Polymers, 'Petru Poni' Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 12; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 12.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*chemistry
Coated Materials, Biocompatible/*chemistry
Cochlear Implants/*microbiology
Otitis/*drug therapy
Polymers/*chemistry
Siloxanes/*chemistry
Acetylcysteine/chemistry ; Acetylcysteine/pharmacology ; Acetylcysteine/therapeutic use ; Animals ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Bacterial Adhesion/drug effects ; Biofilms/drug effects ; Coated Materials, Biocompatible/pharmacology ; Coated Materials, Biocompatible/therapeutic use ; Cochlear Implants/adverse effects ; Polymers/pharmacology ; Polymers/therapeutic use ; Rats, Wistar ; Siloxanes/pharmacology ; Siloxanes/therapeutic use ; Streptococcus pneumoniae/drug effects ; Sulfhydryl Compounds/chemistry ; Surface Properties
Czasopismo naukowe
Tytuł :
Effect of Oral Azithromycin vs Placebo on COVID-19 Symptoms in Outpatients With SARS-CoV-2 Infection: A Randomized Clinical Trial.
Autorzy :
Oldenburg CE; Francis I. Proctor Foundation, University of California, San Francisco.; Department of Ophthalmology, University of California, San Francisco.; Department of Epidemiology and Biostatistics, University of California, San Francisco.
Pinsky BA; Department of Pathology, Stanford University School of Medicine, Stanford, California.; Clinical Virology Laboratory, Stanford Health Care, Stanford, California.; Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford School of Medicine, Stanford, California.
Brogdon J; Francis I. Proctor Foundation, University of California, San Francisco.
Chen C; Francis I. Proctor Foundation, University of California, San Francisco.
Ruder K; Francis I. Proctor Foundation, University of California, San Francisco.
Zhong L; Francis I. Proctor Foundation, University of California, San Francisco.
Nyatigo F; Francis I. Proctor Foundation, University of California, San Francisco.
Cook CA; Francis I. Proctor Foundation, University of California, San Francisco.
Hinterwirth A; Francis I. Proctor Foundation, University of California, San Francisco.
Lebas E; Francis I. Proctor Foundation, University of California, San Francisco.
Redd T; Francis I. Proctor Foundation, University of California, San Francisco.; Department of Ophthalmology, University of California, San Francisco.
Porco TC; Francis I. Proctor Foundation, University of California, San Francisco.; Department of Ophthalmology, University of California, San Francisco.; Department of Epidemiology and Biostatistics, University of California, San Francisco.
Lietman TM; Francis I. Proctor Foundation, University of California, San Francisco.; Department of Ophthalmology, University of California, San Francisco.; Department of Epidemiology and Biostatistics, University of California, San Francisco.
Arnold BF; Francis I. Proctor Foundation, University of California, San Francisco.; Department of Ophthalmology, University of California, San Francisco.
Doan T; Francis I. Proctor Foundation, University of California, San Francisco.; Department of Ophthalmology, University of California, San Francisco.
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Źródło :
JAMA [JAMA] 2021 Aug 10; Vol. 326 (6), pp. 490-498.
Typ publikacji :
Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
SARS-CoV-2*
Anti-Bacterial Agents/*therapeutic use
Azithromycin/*therapeutic use
COVID-19/*drug therapy
Administration, Oral ; Adult ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/adverse effects ; Azithromycin/administration & dosage ; Azithromycin/adverse effects ; COVID-19/complications ; Female ; Humans ; Male ; Middle Aged ; Outpatients ; Symptom Assessment ; Treatment Failure
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp.
Autorzy :
Goldberg JA; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 44106, USA.
Kumar V; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA.
Spencer EJ; Yale Center for Molecular Discovery, West Haven, CT, 06516, USA.
Hoyer D; Yale Center for Molecular Discovery, West Haven, CT, 06516, USA.
Marshall SH; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 44106, USA.
Hujer AM; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 44106, USA; Department of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
Hujer KM; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 44106, USA; Department of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
Bethel CR; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 44106, USA.
Papp-Wallace KM; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 44106, USA; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA; Department of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.
Perez F; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 44106, USA; Department of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA; Geriatric Research, Education and Clinical Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 44106, USA.
Jacobs MR; Department of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA; Department of Pathology, University Hospitals Cleveland Medical Center, Division of Clinical Microbiology, Cleveland, OH, 44106, USA.
van Duin D; University of North Carolina School of Medicine, Chapel Hill, NC, 27514, USA.
Kreiswirth BN; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, 07601, USA.
van den Akker F; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA. Electronic address: .
Plummer MS; Yale Center for Molecular Discovery, West Haven, CT, 06516, USA. Electronic address: .
Bonomo RA; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 44106, USA; Department of Biochemistry, Case Western Reserve University, Cleveland, OH, 44106, USA; Department of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA; Geriatric Research, Education and Clinical Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, 44106, USA; Departments of Pharmacology, Molecular Biology & Microbiology, And Proteomics & Bioinformatics, Case Western Reserve University, Cleveland, OH, 44106, USA; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, OH, 44106, USA. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Aug 05; Vol. 220, pp. 113436. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Drug Resistance, Multiple, Bacterial/*drug effects
Klebsiella pneumoniae/*drug effects
Lactams/*pharmacology
Siderophores/*pharmacology
Acinetobacter baumannii/drug effects ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Dose-Response Relationship, Drug ; Lactams/chemical synthesis ; Lactams/chemistry ; Microbial Sensitivity Tests ; Molecular Structure ; Pseudomonas aeruginosa/drug effects ; Siderophores/chemical synthesis ; Siderophores/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Essential Oils Extracted from Organic Propolis Residues: An Exploratory Analysis of Their Antibacterial and Antioxidant Properties and Volatile Profile.
Autorzy :
Ikeda NY; Department of Agri-Food Industry, Food and Nutrition, 'Luiz de Queiroz' College of Agriculture, University of São Paulo, Piracicaba, São Paulo 13418-900, SP, Brazil.
Ambrosio CMS; Dirección de Investigación y Desarrollo, Universidad Privada del Norte (UPN), Trujillo 13011, Peru.
Miano AC; Dirección de Investigación y Desarrollo, Universidad Privada del Norte (UPN), Trujillo 13011, Peru.
Rosalen PL; Biological Sciences Graduate Program, Federal University of Alfenas-UNIFAL-MG, Rua Gabriel Monteiro da Silva, 700, Alfenas 37130-001, MG, Brazil.; Department of Biosciences, Piracicaba Dental School, University of Campinas, Av. Limeira, 901, Piracicaba 13414-903, SP, Brazil.
Gloria EM; Department of Biosciences, Piracicaba Dental School, University of Campinas, Av. Limeira, 901, Piracicaba 13414-903, SP, Brazil.; Department of Biological Science, 'Luiz de Queiroz' College of Agriculture, University of São Paulo, Piracicaba, São Paulo 13418-900, SP, Brazil.
Alencar SM; Department of Agri-Food Industry, Food and Nutrition, 'Luiz de Queiroz' College of Agriculture, University of São Paulo, Piracicaba, São Paulo 13418-900, SP, Brazil.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 03; Vol. 26 (15). Date of Electronic Publication: 2021 Aug 03.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents*/chemistry
Anti-Bacterial Agents*/isolation & purification
Anti-Bacterial Agents*/pharmacology
Antioxidants*/chemistry
Antioxidants*/isolation & purification
Antioxidants*/pharmacology
Oils, Volatile*/chemistry
Oils, Volatile*/isolation & purification
Oils, Volatile*/pharmacology
Escherichia coli/*growth & development
Lactobacillus plantarum/*growth & development
Propolis/*chemistry
Czasopismo naukowe
Tytuł :
Real-World Use of Dalbavancin in the Era of Empowerment of Outpatient Antimicrobial Treatment: A Careful Appraisal Beyond Approved Indications Focusing on Unmet Clinical Needs.
Autorzy :
Gatti M; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.; SSD Clinical Pharmacology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Andreoni M; Department of Systems Medicine, University of Rome 'Tor Vergata', Rome, Italy.; Infectious Diseases Clinic, University Hospital 'Tor Vergata', Rome, Italy.
Pea F; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.; SSD Clinical Pharmacology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Viale P; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.; Infectious Disease Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
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Źródło :
Drug design, development and therapy [Drug Des Devel Ther] 2021 Aug 03; Vol. 15, pp. 3349-3378. Date of Electronic Publication: 2021 Aug 03 (Print Publication: 2021).
Typ publikacji :
Journal Article; Review
MeSH Terms :
Ambulatory Care*
COVID-19*
Off-Label Use*
Patient Participation*
Anti-Bacterial Agents/*therapeutic use
Gram-Positive Bacterial Infections/*drug therapy
Teicoplanin/*analogs & derivatives
Algorithms ; Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/pharmacokinetics ; Clinical Decision-Making ; Decision Support Techniques ; Gram-Positive Bacterial Infections/diagnosis ; Gram-Positive Bacterial Infections/microbiology ; Humans ; Teicoplanin/adverse effects ; Teicoplanin/pharmacokinetics ; Teicoplanin/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Design and enantioselective synthesis of 3-(α-acrylic acid) benzoxaboroles to combat carbapenemase resistance.
Autorzy :
Xiao YC; Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. .
Chen XP; Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. .
Deng J; Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. .
Yan YH; Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. .
Zhu KR; Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. .
Li G; Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. .
Yu JL; Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. .
Brem J; Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK. .
Chen F; Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. .
Schofield CJ; Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK. .
Li GB; Key Laboratory of Drug-Targeting and Drug Delivery System of the Ministry of Education and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. .
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Źródło :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 Aug 03; Vol. 57 (62), pp. 7709-7712.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Anti-Bacterial Agents/*chemical synthesis
Anti-Bacterial Agents/*pharmacology
Bacterial Proteins/*pharmacology
Benzoxazoles/*chemical synthesis
Benzoxazoles/*pharmacology
Drug Resistance, Bacterial/*drug effects
beta-Lactamases/*pharmacology
Anti-Bacterial Agents/chemistry ; Benzoxazoles/chemistry ; Chemistry Techniques, Synthetic ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Vancomycin-Functionalized Porphyrinic Metal-Organic Framework PCN-224 with Enhanced Antibacterial Activity against Staphylococcus Aureus.
Autorzy :
Chen LJ; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, P. R. China.; Institute of Analytical Food Safety, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, P. R. China.
Liu YY; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, P. R. China.; Institute of Analytical Food Safety, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, P. R. China.
Zhao X; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, P. R. China.; Institute of Analytical Food Safety, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, P. R. China.
Yan XP; State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, P. R. China.; Institute of Analytical Food Safety, School of Food Science and Technology, Jiangnan University, Wuxi, 214122, P. R. China.; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi, 214122, P. R. China.
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Źródło :
Chemistry, an Asian journal [Chem Asian J] 2021 Aug 02; Vol. 16 (15), pp. 2022-2026. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Metal-Organic Frameworks/*pharmacology
Porphyrins/*pharmacology
Staphylococcus aureus/*drug effects
Vancomycin/*pharmacology
Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Metal-Organic Frameworks/chemical synthesis ; Metal-Organic Frameworks/chemistry ; Microbial Sensitivity Tests ; Molecular Conformation ; Particle Size ; Porphyrins/chemistry ; Surface Properties ; Vancomycin/chemistry
Czasopismo naukowe
Tytuł :
Therapeutic contact lenses fabricated by hyaluronic acid and silver incorporated bovine serum albumin porous films for the treatment of alkali-burned corneal wound.
Autorzy :
Yin C; Department of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, China.
Qi X; Department of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, China.
Wu J; Department of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, China.
Guo C; Department of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, China. Electronic address: .
Wu X; Department of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Zhengzhou Road 53, Qingdao 266042, China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Aug 01; Vol. 184, pp. 713-720. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article
MeSH Terms :
Alkalies/*adverse effects
Anti-Bacterial Agents/*administration & dosage
Corneal Injuries/*drug therapy
Hyaluronic Acid/*administration & dosage
Serum Albumin, Bovine/*chemistry
Silver/*chemistry
Animals ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/therapeutic use ; Bandages ; Contact Lenses, Hydrophilic ; Corneal Injuries/chemically induced ; Disease Models, Animal ; Drug Compounding ; Hyaluronic Acid/chemistry ; Hyaluronic Acid/pharmacology ; Mice ; Molecular Structure ; Porosity ; Treatment Outcome ; Wound Healing/drug effects
Czasopismo naukowe
Tytuł :
Perioperative anaphylaxis to intravenous vancomycin in a pediatric patient with previous topical exposures.
Autorzy :
Xie SS; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio. Electronic address: .
Soler X; Division of Anesthesia, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
Risma KA; Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
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Źródło :
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology [Ann Allergy Asthma Immunol] 2021 Aug; Vol. 127 (2), pp. 264-266. Date of Electronic Publication: 2021 May 07.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Anaphylaxis/*chemically induced
Anti-Bacterial Agents/*immunology
Drug Hypersensitivity/*immunology
Heart Arrest/*pathology
Vancomycin/*immunology
Anaphylaxis/immunology ; Anaphylaxis/pathology ; Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis/methods ; Child ; Drug Hypersensitivity/pathology ; Female ; Humans ; Perioperative Period ; Vancomycin/adverse effects ; Vancomycin/therapeutic use
Raport

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