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Wyszukujesz frazę ""Apoptosis"" wg kryterium: Temat


Tytuł :
Cellular FADD-like IL-1β-converting enzyme-inhibitory protein attenuates myocardial ischemia/reperfusion injury via suppressing apoptosis and autophagy simultaneously.
Autorzy :
Liu D; Institute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China; Department of Cardiology, Yichang Central People's Hospital, Yichang, 443003, China; HuBei Clinical Research Center for Ischemic Cardiovascular Disease, Yichang, 443003, China.
Wu H; Institute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China; Department of Cardiology, Yichang Central People's Hospital, Yichang, 443003, China; HuBei Clinical Research Center for Ischemic Cardiovascular Disease, Yichang, 443003, China. Electronic address: .
Li YZ; Institute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China; Department of Cardiology, Yichang Central People's Hospital, Yichang, 443003, China; HuBei Clinical Research Center for Ischemic Cardiovascular Disease, Yichang, 443003, China.
Yang J; Institute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China; Department of Cardiology, Yichang Central People's Hospital, Yichang, 443003, China; HuBei Clinical Research Center for Ischemic Cardiovascular Disease, Yichang, 443003, China.
Yang J; Institute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China.
Ding JW; Institute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China; Department of Cardiology, Yichang Central People's Hospital, Yichang, 443003, China; HuBei Clinical Research Center for Ischemic Cardiovascular Disease, Yichang, 443003, China.
Zhou G; Institute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China; Department of Cardiology, Yichang Central People's Hospital, Yichang, 443003, China; HuBei Clinical Research Center for Ischemic Cardiovascular Disease, Yichang, 443003, China.
Zhang J; Department of Cardiology, Yichang Central People's Hospital, Yichang, 443003, China; HuBei Clinical Research Center for Ischemic Cardiovascular Disease, Yichang, 443003, China; Department of Central Experimental Laboratory, Yichang Central People's Hospital, Yichang, 443003, China.
Wang X; Institute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China; Department of Cardiology, Yichang Central People's Hospital, Yichang, 443003, China; HuBei Clinical Research Center for Ischemic Cardiovascular Disease, Yichang, 443003, China.
Fan ZX; Institute of Cardiovascular Disease, China Three Gorges University, Yichang, 443003, China.
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Źródło :
Nutrition, metabolism, and cardiovascular diseases : NMCD [Nutr Metab Cardiovasc Dis] 2021 Jun 07; Vol. 31 (6), pp. 1916-1928. Date of Electronic Publication: 2021 Mar 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Autophagy*
CASP8 and FADD-Like Apoptosis Regulating Protein/*metabolism
Myocardial Infarction/*prevention & control
Myocardial Reperfusion Injury/*prevention & control
Myocytes, Cardiac/*metabolism
Animals ; Apoptosis Regulatory Proteins/metabolism ; Autophagy-Related Proteins/metabolism ; CASP8 and FADD-Like Apoptosis Regulating Protein/genetics ; Cells, Cultured ; Disease Models, Animal ; Male ; Myocardial Infarction/metabolism ; Myocardial Infarction/pathology ; Myocardial Reperfusion Injury/genetics ; Myocardial Reperfusion Injury/metabolism ; Myocardial Reperfusion Injury/pathology ; Myocytes, Cardiac/pathology ; NF-kappa B/metabolism ; Rats, Sprague-Dawley ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Tytuł :
Reconstruction of the Fas-Based Death-Inducing Signaling Complex (DISC) Using a Protein-Protein Docking Meta-Approach.
Autorzy :
Mahdizadeh SJ; Department of Chemistry and Molecular Biology, University of Gothenburg, 405 30 Göteborg, Sweden.
Thomas M; Department of Chemistry and Molecular Biology, University of Gothenburg, 405 30 Göteborg, Sweden.
Eriksson LA; Department of Chemistry and Molecular Biology, University of Gothenburg, 405 30 Göteborg, Sweden.
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Źródło :
Journal of chemical information and modeling [J Chem Inf Model] 2021 Jul 26; Vol. 61 (7), pp. 3543-3558. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Signal Transduction*
Death Domain Receptor Signaling Adaptor Proteins/*chemistry
CASP8 and FADD-Like Apoptosis Regulating Protein/chemistry ; Caspase 8 ; Cell Membrane/chemistry ; Fas-Associated Death Domain Protein/chemistry ; Protein Interaction Mapping
Czasopismo naukowe
Tytuł :
Clustering of Death Receptor for Apoptosis Using Nanoscale Patterns of Peptides.
Autorzy :
Wang Y; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden.
Baars I; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden.
Fördös F; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden.
Högberg B; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-17177 Stockholm, Sweden.
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Źródło :
ACS nano [ACS Nano] 2021 Jun 22; Vol. 15 (6), pp. 9614-9626. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Receptors, TNF-Related Apoptosis-Inducing Ligand*
TNF-Related Apoptosis-Inducing Ligand*
Apoptosis ; Cluster Analysis ; Humans ; Peptides ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł :
[Effect of DR4 Demethylation to the Proliferation and Apoptosis of Myeloid Leukemia K562 Cells].
Autorzy :
Zhang M; Department of Hematology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, Henan Province, China.
Cai LH; Department of Hematology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, Henan Province, China.
Yang HP; Department of Hematology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, Henan Province, China,E-mail:.
Yang XW; Department of Hematology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, Henan Province, China.
Si XH; Xinxiang Medical College, Xinxiang 453003, Henan Province, China.
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Źródło :
Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2021 Apr; Vol. 29 (2), pp. 422-427.
Typ publikacji :
Journal Article
MeSH Terms :
Leukemia, Myeloid*
Receptors, TNF-Related Apoptosis-Inducing Ligand*/metabolism
Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Demethylation ; Humans ; K562 Cells ; TNF-Related Apoptosis-Inducing Ligand/metabolism
Czasopismo naukowe
Tytuł :
H 2 O 2 mediated FLIP and XIAP down-regulation involves increased ITCH expression and ERK-Akt crosstalk in imatinib resistant Chronic Myeloid Leukemia cell line K562.
Autorzy :
Paul T; Department of Life Sciences, Presidency University, Kolkata, India.
Roy R; Department of Life Sciences, Presidency University, Kolkata, India.
Sarkar RD; Department of Life Sciences, Presidency University, Kolkata, India.
Sinha S; Department of Life Sciences, Presidency University, Kolkata, India.
Biswas N; Department of Life Sciences, Presidency University, Kolkata, India. Electronic address: .
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2021 Apr; Vol. 166, pp. 265-276. Date of Electronic Publication: 2021 Feb 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CASP8 and FADD-Like Apoptosis Regulating Protein*/genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/genetics
Apoptosis ; Cell Line, Tumor ; Down-Regulation ; Humans ; Hydrogen Peroxide ; Imatinib Mesylate/pharmacology ; K562 Cells ; Proto-Oncogene Proteins c-akt/genetics ; X-Linked Inhibitor of Apoptosis Protein/genetics ; X-Linked Inhibitor of Apoptosis Protein/metabolism
Czasopismo naukowe
Tytuł :
TRAIL-Armed ER Nanosomes Induce Drastically Enhanced Apoptosis in Resistant Tumor in Combination with the Antagonist of IAPs (AZD5582).
Autorzy :
Hou H; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 51006, China.
Su K; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 51006, China.
Huang C; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 51006, China.
Yuan Q; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 51006, China.
Li S; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 51006, China.
Sun J; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 51006, China.
Lin Y; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 51006, China.
Du Z; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 51006, China.
Ke C; YZ Health-tech Inc., Hengqin District, Zhuhai, 519000, China.; School of Pharmacy, Jinan University, Guangzhou, 510632, China.
Yuan Z; School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 51006, China.
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Źródło :
Advanced healthcare materials [Adv Healthc Mater] 2021 Jun; Vol. 10 (11), pp. e2100030. Date of Electronic Publication: 2021 May 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasms*
TNF-Related Apoptosis-Inducing Ligand*
Alkynes ; Apoptosis ; Cell Line, Tumor ; Endoplasmic Reticulum ; Humans ; Oligopeptides
Czasopismo naukowe
Tytuł :
Effect of circular-RNA30741 on apoptosis of rat primary cardiomyocytes by regulating MiR-21.
Autorzy :
Pan J; Department of Cardiology, Liaocheng People's Hospital, Liaocheng, China.
Feng Y; Department of Cardiology, Liaocheng Third People's Hospital, Liaocheng, China.
Guo Y; Department of Cardiology, Liaocheng Third People's Hospital, Liaocheng, China.
Kong X; Department of Cardiology, Linqing People's Hospital, Linqing, China - .
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Źródło :
Minerva medica [Minerva Med] 2021 Apr; Vol. 112 (2), pp. 306-308. Date of Electronic Publication: 2019 Jul 17.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
MicroRNAs/*metabolism
Myocardial Infarction/*metabolism
Myocytes, Cardiac/*metabolism
RNA, Circular/*metabolism
Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Apoptosis Regulatory Proteins/metabolism ; Cell Survival ; Down-Regulation ; High-Throughput Screening Assays ; Intracellular Signaling Peptides and Proteins/metabolism ; MicroRNAs/blood ; Microarray Analysis/methods ; Myocardial Infarction/blood ; Myocytes, Cardiac/cytology ; Rats ; Smad7 Protein/metabolism ; Up-Regulation
Czasopismo naukowe
Tytuł :
Overcoming therapeutic efficiency limitations against TRAIL-resistant tumors using re-sensitizing agent-loaded trimeric TRAIL-presenting nanocages.
Autorzy :
Je H; Department of Chemical Engineering, School of Applied Chemical Engineering, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Republic of Korea.
Nam GH; Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
Kim GB; Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea; KU-KIST Graduate School of Converging Science and Technology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Kim W; Department of Chemical Engineering, School of Applied Chemical Engineering, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Republic of Korea.
Kim SR; School of Food Science and Biotechnology, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Republic of Korea.
Kim IS; Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea; KU-KIST Graduate School of Converging Science and Technology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea. Electronic address: .
Lee EJ; Department of Chemical Engineering, School of Applied Chemical Engineering, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Republic of Korea. Electronic address: .
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Źródło :
Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2021 Mar 10; Vol. 331, pp. 7-18. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasms*/drug therapy
TNF-Related Apoptosis-Inducing Ligand*
Apoptosis ; Cell Line, Tumor ; Doxorubicin ; Humans ; Receptors, TNF-Related Apoptosis-Inducing Ligand
Czasopismo naukowe
Tytuł :
The 89-kDa PARP1 cleavage fragment serves as a cytoplasmic PAR carrier to induce AIF-mediated apoptosis.
Autorzy :
Mashimo M; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan. Electronic address: .
Onishi M; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
Uno A; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
Tanimichi A; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
Nobeyama A; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
Mori M; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
Yamada S; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
Negi S; Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
Bu X; Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Kato J; Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Moss J; Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Sanada N; Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
Kizu R; Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
Fujii T; Department of Pharmacology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kyotanabe, Kyoto, Japan.
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2021 Jan-Jun; Vol. 296, pp. 100046. Date of Electronic Publication: 2020 Nov 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Proteolysis*
Apoptosis Inducing Factor/*metabolism
Poly (ADP-Ribose) Polymerase-1/*metabolism
Poly Adenosine Diphosphate Ribose/*metabolism
Apoptosis Inducing Factor/genetics ; Biological Transport, Active ; Caspase 3/genetics ; Caspase 3/metabolism ; Caspase 7/genetics ; Caspase 7/metabolism ; Cytoplasm/genetics ; Cytoplasm/metabolism ; HeLa Cells ; Humans ; Poly (ADP-Ribose) Polymerase-1/genetics ; Poly Adenosine Diphosphate Ribose/genetics
Czasopismo naukowe
Tytuł :
Enhancing the Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Signaling and Arginine Deprivation in Melanoma.
Autorzy :
Wu C; Department of Veterans Affairs, Miami VA Healthcare System, Research Service, Miami, FL 33125, USA.
You M; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Nguyen D; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.; Department of Surgery, Cardiothoracic Surgery, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Wangpaichitr M; Department of Veterans Affairs, Miami VA Healthcare System, Research Service, Miami, FL 33125, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.; Department of Surgery, Cardiothoracic Surgery, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Li YY; Department of Veterans Affairs, Miami VA Healthcare System, Research Service, Miami, FL 33125, USA.
Feun LG; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.; Department of Medicine, Hematology/Oncology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Kuo MT; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Savaraj N; Department of Veterans Affairs, Miami VA Healthcare System, Research Service, Miami, FL 33125, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.; Department of Medicine, Hematology/Oncology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 16; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Hydrolases/*pharmacology
Melanoma/*metabolism
TNF-Related Apoptosis-Inducing Ligand/*pharmacology
Apoptosis/drug effects ; Arginine/deficiency ; Arginine/metabolism ; Autophagy/drug effects ; Cell Line, Tumor ; Drug Resistance, Neoplasm/drug effects ; Humans ; Hydrolases/metabolism ; Polyethylene Glycols/metabolism ; Polyethylene Glycols/pharmacology ; Signal Transduction/drug effects ; TNF-Related Apoptosis-Inducing Ligand/genetics ; TNF-Related Apoptosis-Inducing Ligand/metabolism
Czasopismo naukowe
Tytuł :
Thymoquinone sensitizes human hepatocarcinoma cells to TRAIL-induced apoptosis via oxidative DNA damage.
Autorzy :
Zhang R; Department of Special Emergency Surgery, Special Medical Center of Chinese People 's Armed Police Forces, Tianjin, 300162, China.
Wu T; Department of Infectious Disease, Hainan General Hospital, Haikou, Hainan, 570311, China.
Zheng P; Department of General Surgery, the First Hospital Affiliated of Shandong First Medical University (Qianfoshan Hospital), Jinan, Shandong, 250014, China.
Liu M; Department of Infectious Disease, Hainan General Hospital, Haikou, Hainan, 570311, China.
Xu G; Department of General Surgery, Qingdao Fuwai Hospital Qingdao, Shandong, 266034, China.
Xi M; Department of Urology, Huadu District People's Hospital, Southern Medical University, Guangzhou, Guangdong, 510800, China.
Yu J; Department of General Surgery, the First Hospital Affiliated of Shandong First Medical University (Qianfoshan Hospital), Jinan, Shandong, 250014, China. Electronic address: .
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Źródło :
DNA repair [DNA Repair (Amst)] 2021 Jul; Vol. 103, pp. 103117. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
DNA Damage*
Benzoquinones/*pharmacology
Carcinoma, Hepatocellular/*drug therapy
Liver Neoplasms/*drug therapy
TNF-Related Apoptosis-Inducing Ligand/*metabolism
Benzoquinones/therapeutic use ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/physiopathology ; DNA/drug effects ; Hep G2 Cells ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Liver Neoplasms/physiopathology ; Oxidative Stress
Czasopismo naukowe
Tytuł :
Downregulation of ARID1A in gastric cancer cells: a putative protective molecular mechanism against the Harakiri-mediated apoptosis pathway.
Autorzy :
Sakuratani T; Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan.
Takeuchi T; Department of Pathology and Translational Research, Gifu University Graduate School of Medicine, Gifu, 501-1193, Japan. .
Yasufuku I; Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan.
Iwata Y; Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan.
Saigo C; Department of Pathology and Translational Research, Gifu University Graduate School of Medicine, Gifu, 501-1193, Japan.
Kito Y; Department of Pathology and Translational Research, Gifu University Graduate School of Medicine, Gifu, 501-1193, Japan.
Yoshida K; Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 Mar; Vol. 478 (3), pp. 401-411. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/drug effects
Apoptosis Regulatory Proteins/*metabolism
Biomarkers, Tumor/*metabolism
DNA-Binding Proteins/*metabolism
Stomach Neoplasms/*metabolism
Transcription Factors/*metabolism
Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/pharmacology ; Apoptosis Regulatory Proteins/genetics ; Biomarkers, Tumor/genetics ; Caprylates/pharmacology ; Cell Line, Tumor ; DNA-Binding Proteins/genetics ; Down-Regulation ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Signal Transduction ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/genetics ; Stomach Neoplasms/pathology ; Sulfides/pharmacology ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Nradd Acts as a Negative Feedback Regulator of Wnt/β-Catenin Signaling and Promotes Apoptosis.
Autorzy :
Ozalp O; Izmir Biomedicine and Genome Center (IBG), Dokuz Eylul University Health Campus, Inciralti-Balcova, 35340 Izmir, Turkey.; Izmir International Biomedicine and Genome Institute (IBG-Izmir), Dokuz Eylul University, Inciralti-Balcova, 35340 Izmir, Turkey.
Cark O; Izmir Biomedicine and Genome Center (IBG), Dokuz Eylul University Health Campus, Inciralti-Balcova, 35340 Izmir, Turkey.; Izmir International Biomedicine and Genome Institute (IBG-Izmir), Dokuz Eylul University, Inciralti-Balcova, 35340 Izmir, Turkey.
Azbazdar Y; Izmir Biomedicine and Genome Center (IBG), Dokuz Eylul University Health Campus, Inciralti-Balcova, 35340 Izmir, Turkey.; Izmir International Biomedicine and Genome Institute (IBG-Izmir), Dokuz Eylul University, Inciralti-Balcova, 35340 Izmir, Turkey.
Haykir B; Izmir Biomedicine and Genome Center (IBG), Dokuz Eylul University Health Campus, Inciralti-Balcova, 35340 Izmir, Turkey.; Institute of Physiology, Switzerland and National Center of Competence in Research NCCR Kidney, University of Zurich, CH-8057 Zurich, Switzerland.
Cucun G; Izmir Biomedicine and Genome Center (IBG), Dokuz Eylul University Health Campus, Inciralti-Balcova, 35340 Izmir, Turkey.; Izmir International Biomedicine and Genome Institute (IBG-Izmir), Dokuz Eylul University, Inciralti-Balcova, 35340 Izmir, Turkey.
Kucukaylak I; Izmir Biomedicine and Genome Center (IBG), Dokuz Eylul University Health Campus, Inciralti-Balcova, 35340 Izmir, Turkey.; Institute of Zoology-Developmental Biology, University of Cologne, 50674 Cologne, Germany.
Alkan-Yesilyurt G; Izmir Biomedicine and Genome Center (IBG), Dokuz Eylul University Health Campus, Inciralti-Balcova, 35340 Izmir, Turkey.
Sezgin E; Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, 17177 Stockholm, Sweden.; MRC Weatherall Institute of Molecular Medicine, MRC Human Immunology Unit, University of Oxford, Oxford OX39DS, UK.
Ozhan G; Izmir Biomedicine and Genome Center (IBG), Dokuz Eylul University Health Campus, Inciralti-Balcova, 35340 Izmir, Turkey.; Izmir International Biomedicine and Genome Institute (IBG-Izmir), Dokuz Eylul University, Inciralti-Balcova, 35340 Izmir, Turkey.
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Źródło :
Biomolecules [Biomolecules] 2021 Jan 14; Vol. 11 (1). Date of Electronic Publication: 2021 Jan 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*/genetics
Feedback, Physiological*
Wnt Signaling Pathway*/genetics
Apoptosis Regulatory Proteins/*metabolism
Zebrafish Proteins/*metabolism
Animals ; Apoptosis Regulatory Proteins/genetics ; Cell Line ; Cell Membrane/metabolism ; Ectoderm/embryology ; Ectoderm/metabolism ; Embryonic Development/genetics ; Gene Expression Regulation, Developmental ; Humans ; Mesoderm/embryology ; Mesoderm/metabolism ; Protein Binding ; Transcription, Genetic ; Zebrafish/embryology ; Zebrafish/genetics ; Zebrafish Proteins/genetics
Czasopismo naukowe
Tytuł :
Cardiac telocytes inhibit cardiac microvascular endothelial cell apoptosis through exosomal miRNA-21-5p-targeted cdip1 silencing to improve angiogenesis following myocardial infarction.
Autorzy :
Liao Z; The First Affiliated Hospital, Key Laboratory of Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China.
Chen Y; Key Laboratory of Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China.; Joint Laboratory for Regenerative Medicine, Chinese University of Hong Kong-Jinan University, Guangzhou 510632, China.; International Base of Collaboration for Science and Technology (JNU), Ministry of Science and Technology, Guangdong Province, Guangzhou 510632, China.; Department of Developmental and Regenerative Biology, Jinan University, Guangzhou 510632, China.
Duan C; Key Laboratory of Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China.; Joint Laboratory for Regenerative Medicine, Chinese University of Hong Kong-Jinan University, Guangzhou 510632, China.; International Base of Collaboration for Science and Technology (JNU), Ministry of Science and Technology, Guangdong Province, Guangzhou 510632, China.; Department of Developmental and Regenerative Biology, Jinan University, Guangzhou 510632, China.
Zhu K; Key Laboratory of Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China.; Joint Laboratory for Regenerative Medicine, Chinese University of Hong Kong-Jinan University, Guangzhou 510632, China.; International Base of Collaboration for Science and Technology (JNU), Ministry of Science and Technology, Guangdong Province, Guangzhou 510632, China.; Department of Developmental and Regenerative Biology, Jinan University, Guangzhou 510632, China.
Huang R; Institute of Anatomy, Department of Neuroanatomy, University of Bonn, Germany.
Zhao H; Stem Cell and Regeneration TRP, School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong.
Hintze M; Institute of Anatomy, Department of Neuroanatomy, University of Bonn, Germany.; Medical Department, MSH Medical School Hamburg, Germany.
Pu Q; Institute of Anatomy, Department of Neuroanatomy, University of Bonn, Germany.
Yuan Z; Cancer Institute of New Jersey, Department of Medical Oncology, Robert Wood Johnson of Medical School, USA.
Lv L; Key Laboratory of Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China.; Joint Laboratory for Regenerative Medicine, Chinese University of Hong Kong-Jinan University, Guangzhou 510632, China.; International Base of Collaboration for Science and Technology (JNU), Ministry of Science and Technology, Guangdong Province, Guangzhou 510632, China.; Department of Developmental and Regenerative Biology, Jinan University, Guangzhou 510632, China.
Chen H; Key Laboratory of Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China.; Joint Laboratory for Regenerative Medicine, Chinese University of Hong Kong-Jinan University, Guangzhou 510632, China.; International Base of Collaboration for Science and Technology (JNU), Ministry of Science and Technology, Guangdong Province, Guangzhou 510632, China.; Department of Developmental and Regenerative Biology, Jinan University, Guangzhou 510632, China.
Lai B; Key Laboratory of Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China.; Joint Laboratory for Regenerative Medicine, Chinese University of Hong Kong-Jinan University, Guangzhou 510632, China.; International Base of Collaboration for Science and Technology (JNU), Ministry of Science and Technology, Guangdong Province, Guangzhou 510632, China.; Department of Developmental and Regenerative Biology, Jinan University, Guangzhou 510632, China.
Feng S; Key Laboratory of Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China.; Joint Laboratory for Regenerative Medicine, Chinese University of Hong Kong-Jinan University, Guangzhou 510632, China.; International Base of Collaboration for Science and Technology (JNU), Ministry of Science and Technology, Guangdong Province, Guangzhou 510632, China.; Department of Developmental and Regenerative Biology, Jinan University, Guangzhou 510632, China.
Qi X; Key Laboratory of Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China.; Joint Laboratory for Regenerative Medicine, Chinese University of Hong Kong-Jinan University, Guangzhou 510632, China.; International Base of Collaboration for Science and Technology (JNU), Ministry of Science and Technology, Guangdong Province, Guangzhou 510632, China.; Department of Developmental and Regenerative Biology, Jinan University, Guangzhou 510632, China.
Cai D; Key Laboratory of Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou 510632, China.; Joint Laboratory for Regenerative Medicine, Chinese University of Hong Kong-Jinan University, Guangzhou 510632, China.; International Base of Collaboration for Science and Technology (JNU), Ministry of Science and Technology, Guangdong Province, Guangzhou 510632, China.; Department of Developmental and Regenerative Biology, Jinan University, Guangzhou 510632, China.
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Źródło :
Theranostics [Theranostics] 2021 Jan 01; Vol. 11 (1), pp. 268-291. Date of Electronic Publication: 2021 Jan 01 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Neovascularization, Physiologic*
Endothelial Cells/*metabolism
Exosomes/*metabolism
MicroRNAs/*metabolism
Myocardial Infarction/*metabolism
Myocardium/*metabolism
Regeneration/*physiology
Telocytes/*metabolism
Animals ; Apoptosis Regulatory Proteins/genetics ; Apoptosis Regulatory Proteins/metabolism ; Cell Survival ; Culture Media, Conditioned ; Microvessels ; Myocardial Infarction/pathology ; Myocardium/pathology ; Rats ; Telocytes/physiology
Czasopismo naukowe
Tytuł :
10-O-(N N-Dimethylaminoethyl)-Ginkgolide B Methane-Sulfonate (XQ-1H) Ameliorates Cerebral Ischemia Via Suppressing Neuronal Apoptosis.
Autorzy :
Khadankhuu B; State Key Laboratory of Natural Medicines, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China; Mongolian University of Pharmaceutical Sciences, Ulaanbaatar 18130, Mongolia.
Fei Y; State Key Laboratory of Natural Medicines, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Li X; State Key Laboratory of Natural Medicines, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Fang W; State Key Laboratory of Natural Medicines, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Li Y; State Key Laboratory of Natural Medicines, Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2021 Sep; Vol. 30 (9), pp. 105987. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Brain/*drug effects
Ginkgolides/*pharmacology
Infarction, Middle Cerebral Artery/*drug therapy
Lactones/*pharmacology
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Reperfusion Injury/*prevention & control
Animals ; Apoptosis Regulatory Proteins/metabolism ; Behavior, Animal/drug effects ; Brain/metabolism ; Brain/pathology ; Brain/physiopathology ; Brain Edema/metabolism ; Brain Edema/pathology ; Brain Edema/prevention & control ; Disease Models, Animal ; Infarction, Middle Cerebral Artery/metabolism ; Infarction, Middle Cerebral Artery/pathology ; Infarction, Middle Cerebral Artery/physiopathology ; Male ; Motor Activity/drug effects ; Neurons/metabolism ; Neurons/pathology ; PC12 Cells ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/metabolism ; Reperfusion Injury/pathology ; Reperfusion Injury/physiopathology ; Signal Transduction
Czasopismo naukowe
Tytuł :
1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea Exerts Neuro-Protective Effects Against Ischemic Injury via Suppressing JNK/p38 MAPK-Mediated Mitochondrial Apoptosis Pathway.
Autorzy :
Yi X; Department of Neurology, People's Hospital of Deyang City, Deyang, China.
Fan D; Department of Neurology, the Affiliated Longyan first Hospital of Fujian Medical University, Longyan, China.
Yi T; Department of Neurology, the Second People's Hospital of Deyang City, Deyang, China.
Chen H; Department of Neurology, People's Hospital of Deyang City, Deyang, China.
Qing T; Department of Neurology, People's Hospital of Deyang City, Deyang, China.
Han Z; Department of Neurology, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Bao S; Department of Neurology, the Third Affiliated Hospital of Wenzhou Medical University, Zhejiang, China. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2021 Sep; Vol. 30 (9), pp. 105957. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Cerebral Cortex/*drug effects
Ischemic Stroke/*drug therapy
JNK Mitogen-Activated Protein Kinases/*metabolism
Mitochondria/*drug effects
Neurons/*drug effects
Neuroprotective Agents/*pharmacology
Phenylurea Compounds/*pharmacology
Piperidines/*pharmacology
p38 Mitogen-Activated Protein Kinases/*metabolism
Animals ; Apoptosis Regulatory Proteins/metabolism ; Cells, Cultured ; Cerebral Cortex/enzymology ; Cerebral Cortex/ultrastructure ; Ischemic Stroke/enzymology ; Ischemic Stroke/pathology ; Mitochondria/enzymology ; Mitochondria/ultrastructure ; Neurons/enzymology ; Neurons/ultrastructure ; Phosphorylation ; Rats ; Signal Transduction
Czasopismo naukowe
Tytuł :
TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Is Upregulated in Lymphocytes Stimulated with Concanavalin A.
Autorzy :
Simon-Molas H; Departament de Ciències Fisiològiques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, C/Feixa Llarga, s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Vallvé-Martínez X; Departament de Ciències Fisiològiques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, C/Feixa Llarga, s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Caldera-Quevedo I; Molecular Imaging Department, Beatson Institute-Cancer Research UK, Glasgow G61 1BD, UK.
Fontova P; Departament de Nefrologia, Hospital Universitari de Bellvitge, IDIBELL, 08907 Barcelona, Spain.
Arnedo-Pac C; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), 08036 Barcelona, Spain.
Vidal-Alabró A; Departament de Ciències Fisiològiques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, C/Feixa Llarga, s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.; Departament de Nefrologia, Hospital Universitari de Bellvitge, IDIBELL, 08907 Barcelona, Spain.
Castaño E; Centres Científics i Tecnològics, Universitat de Barcelona, 08907 Barcelona, Spain.
Navarro-Sabaté À; Departament d'Infermeria Fonamental i Medicoquirúrgica, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, 08907 Barcelona, Spain.
Lloberas N; Departament de Nefrologia, Hospital Universitari de Bellvitge, IDIBELL, 08907 Barcelona, Spain.
Bartrons R; Departament de Ciències Fisiològiques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, C/Feixa Llarga, s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Manzano A; Departament de Ciències Fisiològiques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, C/Feixa Llarga, s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 11; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 11.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis Regulatory Proteins/*metabolism
Concanavalin A/*pharmacology
Gene Expression Regulation/*drug effects
Lymphocytes/*metabolism
Mitogens/*pharmacology
Phosphatidylinositol 3-Kinases/*chemistry
Phosphoric Monoester Hydrolases/*metabolism
Proto-Oncogene Proteins c-akt/*antagonists & inhibitors
Apoptosis ; Apoptosis Regulatory Proteins/genetics ; Autophagy ; Glycolysis ; Humans ; Lymphocytes/drug effects ; Pentose Phosphate Pathway ; Phosphoric Monoester Hydrolases/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
ROS-Mediated Apoptosis and Autophagy in Ovarian Cancer Cells Treated with Peanut-Shaped Gold Nanoparticles.
Autorzy :
Piktel E; Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, 15-222, Poland.
Ościłowska I; Department of Medicinal Chemistry, Medical University of Bialystok, Bialystok, 15-222, Poland.
Suprewicz Ł; Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, 15-222, Poland.
Depciuch J; Institute of Nuclear Physics Polish Academy of Sciences, Krakow, PL-31342, Poland.
Marcińczyk N; Department of Biopharmacy, Medical University of Bialystok, Bialystok, 15-222, Poland.
Chabielska E; Department of Biopharmacy, Medical University of Bialystok, Bialystok, 15-222, Poland.
Wolak P; Institute of Medical Sciences, Collegium Medicum, Jan Kochanowski University, Kielce, 25-317, Poland.
Wollny T; Holy Cross Cancer Center in Kielce, Kielce, 25-734, Poland.
Janion M; Institute of Medical Sciences, Collegium Medicum, Jan Kochanowski University, Kielce, 25-317, Poland.
Parlinska-Wojtan M; Institute of Nuclear Physics Polish Academy of Sciences, Krakow, PL-31342, Poland.
Bucki R; Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Bialystok, Bialystok, 15-222, Poland.
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Źródło :
International journal of nanomedicine [Int J Nanomedicine] 2021 Mar 09; Vol. 16, pp. 1993-2011. Date of Electronic Publication: 2021 Mar 09 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/drug effects
Autophagy*/drug effects
Gold/*chemistry
Metal Nanoparticles/*chemistry
Ovarian Neoplasms/*pathology
Reactive Oxygen Species/*metabolism
Apoptosis Regulatory Proteins/metabolism ; Arachis ; Carcinoma, Ovarian Epithelial/drug therapy ; Cell Line, Tumor ; Cell Survival/drug effects ; Female ; Humans ; MAP Kinase Signaling System/drug effects ; Metal Nanoparticles/toxicity ; Metal Nanoparticles/ultrastructure ; Ovarian Neoplasms/drug therapy ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
circFOXO3 protects cardiomyocytes against radiation‑induced cardiotoxicity.
Autorzy :
Qiu Y; Department of Cardiology, Fujian Longyan People's Hospital, Longyan, Fujian 364000, P.R. China.
Xie X; Department of Cardiology, Fujian Longyan People's Hospital, Longyan, Fujian 364000, P.R. China.
Lin L; Department of Cardiology, Fujian Longyan People's Hospital, Longyan, Fujian 364000, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Mar; Vol. 23 (3). Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
DNA Damage*
Cardiotoxicity/*metabolism
Gamma Rays/*adverse effects
Myocytes, Cardiac/*metabolism
RNA, Circular/*metabolism
Radiation Injuries, Experimental/*metabolism
Animals ; Apoptosis Regulatory Proteins/metabolism ; Cardiotoxicity/genetics ; Cardiotoxicity/pathology ; Cell Line ; Humans ; Myocytes, Cardiac/pathology ; Radiation Injuries, Experimental/pathology
Czasopismo naukowe
Tytuł :
Knockdown of MALAT1 Inhibits the Progression of Chronic Periodontitis via Targeting miR-769-5p/HIF3A Axis.
Autorzy :
Chen Q; Department of Stomatology, Zibo Central Hospital, No. 54, Gongqingtuan Road, Zhangdian District, Zibo City Shandong Province 255000, China.
Cao M; Department of Stomatology, Zibo Central Hospital, No. 54, Gongqingtuan Road, Zhangdian District, Zibo City Shandong Province 255000, China.
Ge H; Department of Stomatology, Zibo Central Hospital, No. 54, Gongqingtuan Road, Zhangdian District, Zibo City Shandong Province 255000, China.
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Źródło :
BioMed research international [Biomed Res Int] 2021 Feb 01; Vol. 2021, pp. 8899863. Date of Electronic Publication: 2021 Feb 01 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis Regulatory Proteins*/genetics
Apoptosis Regulatory Proteins*/metabolism
Chronic Periodontitis*/genetics
Chronic Periodontitis*/metabolism
Chronic Periodontitis*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Repressor Proteins*/genetics
Repressor Proteins*/metabolism
Adult ; Apoptosis/genetics ; Cell Survival/genetics ; Cells, Cultured ; Female ; Gene Knockdown Techniques ; Gingiva/chemistry ; Gingiva/metabolism ; Humans ; Inflammation/genetics ; Male ; Middle Aged ; Periodontal Ligament/cytology
Czasopismo naukowe

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