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Tytuł :
Salivary Cytokines as Biomarkers for Oral Squamous Cell Carcinoma: A Systematic Review.
Autorzy :
Ferrari E; Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Pezzi ME; Centro Universitario di Odontoiatria, University of Parma, 43125 Parma, Italy.
Cassi D; Dentistry and Oral and Maxillofacial Surgery, Department of Surgical, Medical, Dental and Morphological Science with Interest in Transplant Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, 40100 Modena, Italy.
Pertinhez TA; Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Spisni A; Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.
Meleti M; Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.; Centro Universitario di Odontoiatria, University of Parma, 43125 Parma, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 24; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Journal Article; Meta-Analysis; Review
MeSH Terms :
Biomarkers*
Carcinoma, Squamous Cell/*metabolism
Cytokines/*metabolism
Mouth Neoplasms/*metabolism
Saliva/*metabolism
Biomarkers, Tumor ; Carcinoma, Squamous Cell/diagnosis ; Humans ; Liquid Biopsy/methods ; Mouth Neoplasms/diagnosis ; Prognosis
Czasopismo naukowe
Tytuł :
Laboratory evaluation and prognostication among adults and children with CEBPA-mutant acute myeloid leukemia.
Autorzy :
Mendoza H; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.
Podoltsev NA; Hematology Section, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Siddon AJ; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
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Źródło :
International journal of laboratory hematology [Int J Lab Hematol] 2021 Jul; Vol. 43 Suppl 1, pp. 86-95.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biomarkers, Tumor*
Mutation*
CCAAT-Enhancer-Binding Proteins/*genetics
Leukemia, Myeloid, Acute/*diagnosis
Leukemia, Myeloid, Acute/*genetics
Adult ; Age Factors ; Alleles ; Biomarkers ; CCAAT-Enhancer-Binding Proteins/chemistry ; Child ; Germ-Line Mutation ; Humans ; Protein Binding ; Protein Interaction Domains and Motifs
Czasopismo naukowe
Tytuł :
Development and Validation of a CD8+ T Cell Infiltration-Related Signature for Melanoma Patients.
Autorzy :
Yuan Y; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, United States.; Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, China.
Zhu Z; Department of Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Lan Y; School of Nursing, Yueyang Vocational and Technical College, Yueyang, China.
Duan S; Department of Oncology, The Third Xiangya Hospital of Central South University, Changsha, China.; Xiangya School of Medicine of Central South University, Changsha, China.
Zhu Z; Department of Oncology, The Third Xiangya Hospital of Central South University, Changsha, China.; Xiangya School of Medicine of Central South University, Changsha, China.
Zhang X; Department of Oncology, The Third Xiangya Hospital of Central South University, Changsha, China.
Li G; College of Life Science and Agronomy, Zhoukou Normal University, Zhoukou, China.
Qu H; Department of Plastic Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, China.
Feng Y; Department of Oncology, The Third Xiangya Hospital of Central South University, Changsha, China.
Cai H; Department of Orthopaedics, Loudi Central Hospital, Loudi, China.
Song Z; Department of Oncology, The Third Xiangya Hospital of Central South University, Changsha, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 10; Vol. 12, pp. 659444. Date of Electronic Publication: 2021 May 10 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers*
CD8-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*metabolism
Lymphocytes, Tumor-Infiltrating/*immunology
Lymphocytes, Tumor-Infiltrating/*metabolism
Melanoma/*etiology
Melanoma/*metabolism
Algorithms ; Biomarkers, Tumor ; Computational Biology/methods ; Databases, Genetic ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Humans ; Melanoma/mortality ; Melanoma/pathology ; Mutation ; Prognosis ; Proportional Hazards Models ; Transcriptome ; Tumor Microenvironment/genetics ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
Biomarkers for Cancer Cachexia: A Mini Review.
Autorzy :
Cao Z; Department of Biochemistry and Genetics, La Trobe University, Bundoora, VIC 3086, Australia.
Zhao K; Department of Biochemistry and Genetics, La Trobe University, Bundoora, VIC 3086, Australia.; Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Jose I; Department of Biochemistry and Genetics, La Trobe University, Bundoora, VIC 3086, Australia.
Hoogenraad NJ; Department of Biochemistry and Genetics, La Trobe University, Bundoora, VIC 3086, Australia.; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Melbourne, VIC 3084, Australia.
Osellame LD; Department of Biochemistry and Genetics, La Trobe University, Bundoora, VIC 3086, Australia.; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Melbourne, VIC 3084, Australia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 26; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biomarkers, Tumor*/blood
Biomarkers, Tumor*/metabolism
Cachexia*/diagnosis
Cachexia*/physiopathology
Neoplasms/*complications
Biomarkers/blood ; Biomarkers/metabolism ; Humans ; Muscle, Skeletal/physiopathology ; Risk Factors ; Weight Loss
Czasopismo naukowe
Tytuł :
Exploratory Study Using Urinary Volatile Organic Compounds for the Detection of Hepatocellular Carcinoma.
Autorzy :
Bannaga AS; Department of Gastroenterology and Hepatology, University Hospital, Coventry CV2 2DX, UK.; Warwick Medical School, University of Warwick, Coventry CV4 7HL, UK.
Tyagi H; School of Engineering, University of Warwick, Coventry CV4 7AL, UK.
Daulton E; School of Engineering, University of Warwick, Coventry CV4 7AL, UK.
Covington JA; School of Engineering, University of Warwick, Coventry CV4 7AL, UK.
Arasaradnam RP; Department of Gastroenterology and Hepatology, University Hospital, Coventry CV2 2DX, UK.; Warwick Medical School, University of Warwick, Coventry CV4 7HL, UK.; Faculty of Health & Life Sciences, Coventry University, Coventry CV1 5FB, UK.; Leicester Cancer Research Centre, University of Leicester, Leicester LE1 7RH, UK.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 22; Vol. 26 (9). Date of Electronic Publication: 2021 Apr 22.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers*
Carcinoma, Hepatocellular/*diagnosis
Carcinoma, Hepatocellular/*urine
Liver Neoplasms/*diagnosis
Liver Neoplasms/*urine
Volatile Organic Compounds/*urine
Aged ; Aged, 80 and over ; Biomarkers, Tumor ; Female ; Gas Chromatography-Mass Spectrometry ; Humans ; Ion Mobility Spectrometry ; Liquid Biopsy/methods ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Staging ; ROC Curve ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Urinalysis/methods
Czasopismo naukowe
Tytuł :
Systemic inflammation markers and cancer incidence in the UK Biobank.
Autorzy :
Nøst TH; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, PO Box 6050, 9037, Langnes, Tromsø, Norway. .
Alcala K; Genomic Epidemiology Branch, International Agency for Research on Cancer, 150 Cours Albert Thomas, 69372, Lyon CEDEX 08, France.
Urbarova I; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, PO Box 6050, 9037, Langnes, Tromsø, Norway.
Byrne KS; Genomic Epidemiology Branch, International Agency for Research on Cancer, 150 Cours Albert Thomas, 69372, Lyon CEDEX 08, France.
Guida F; Genomic Epidemiology Branch, International Agency for Research on Cancer, 150 Cours Albert Thomas, 69372, Lyon CEDEX 08, France.
Sandanger TM; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, PO Box 6050, 9037, Langnes, Tromsø, Norway.
Johansson M; Genomic Epidemiology Branch, International Agency for Research on Cancer, 150 Cours Albert Thomas, 69372, Lyon CEDEX 08, France. .
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Źródło :
European journal of epidemiology [Eur J Epidemiol] 2021 Aug; Vol. 36 (8), pp. 841-848. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers/*blood
Inflammation/*blood
Inflammation/*immunology
Neoplasms/*epidemiology
Adult ; Aged ; Biological Specimen Banks ; Biomarkers, Tumor/analysis ; Blood Cell Count ; Cohort Studies ; Female ; Humans ; Incidence ; Lymphocyte Count ; Male ; Middle Aged ; Neoplasms/blood ; Neutrophils/pathology ; Prospective Studies ; United Kingdom/epidemiology
Czasopismo naukowe
Tytuł :
Stereotactic radiotherapy for hepatocellular carcinoma induced by hepatitis C and the relationships of changes in carbohydrate antigen 19-9 with AFP and PIVKA-II.
Autorzy :
Maebayashi T; Department of Radiology, Nihon University School of Medicine, 30-1, Oyaguchi Kami-cho Itabashi-ku, 173-8610 Tokyo, Japan. Electronic address: .
Ishibashi N; Department of Radiology, Nihon University School of Medicine, 30-1, Oyaguchi Kami-cho Itabashi-ku, 173-8610 Tokyo, Japan. Electronic address: .
Aizawa T; Department of Radiology, Nihon University School of Medicine, 30-1, Oyaguchi Kami-cho Itabashi-ku, 173-8610 Tokyo, Japan. Electronic address: .
Sakaguchi M; Department of Radiology, Nihon University School of Medicine, 30-1, Oyaguchi Kami-cho Itabashi-ku, 173-8610 Tokyo, Japan. Electronic address: .
Okada M; Department of Radiology, Nihon University School of Medicine, 30-1, Oyaguchi Kami-cho Itabashi-ku, 173-8610 Tokyo, Japan. Electronic address: .
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Źródło :
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2021 May; Vol. 25 (3), pp. 242-248. Date of Electronic Publication: 2021 Jan 14.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers/*blood
CA-19-9 Antigen/*blood
Carcinoma, Hepatocellular/*radiotherapy
Hepatitis C, Chronic/*complications
Liver Neoplasms/*radiotherapy
Protein Precursors/*blood
alpha-Fetoproteins/*metabolism
Aged ; Aged, 80 and over ; Biomarkers, Tumor/blood ; Carcinoma, Hepatocellular/blood ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/virology ; Female ; Hepatitis C, Chronic/virology ; Humans ; Liver Cirrhosis/complications ; Liver Cirrhosis/virology ; Liver Neoplasms/blood ; Liver Neoplasms/pathology ; Liver Neoplasms/virology ; Male ; Middle Aged ; Neoplasm Recurrence, Local/blood ; Prothrombin
Czasopismo naukowe
Tytuł :
Molecular Targeting of H/MDM-2 Oncoprotein in Human Colon Cancer Cells and Stem-like Colonic Epithelial-derived Progenitor Cells.
Autorzy :
Thadi A; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, U.S.A.
Morano WF; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, U.S.A.
Khalili M; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, U.S.A.
Babcock BD; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, U.S.A.
Shaikh MF; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, U.S.A.
Foster DS; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, U.S.A.
Piazza Y; Department of Pathology and Laboratory Medicine, Drexel University College of Medicine, Philadelphia, PA, U.S.A.
Gleeson EM; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, U.S.A.
Goldstein E; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, U.S.A.
Steele L; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, U.S.A.
Campbell PM; Cancer Signaling and Epigenetics Program, The Marvin and Concetta Greenberg Pancreatic Cancer Institute Fox Chase Cancer Center, Philadelphia, PA, U.S.A.
Lin BO; Department of Pathology and Laboratory Medicine, SUNY Downstate Medical Center, Brooklyn, NY, U.S.A.; .
Pincus MR; Department of Pathology and Laboratory Medicine, SUNY Downstate Medical Center, Brooklyn, NY, U.S.A.; .
Bowne WB; Division of Surgical Oncology, Department of Surgery, Drexel University College of Medicine, Philadelphia, PA, U.S.A.; .; Department of Surgery, Thomas Jefferson University, Philadelphia, PA, U.S.A.
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Źródło :
Anticancer research [Anticancer Res] 2021 Jan; Vol. 41 (1), pp. 27-42.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor*
Antineoplastic Agents/*pharmacology
Colonic Neoplasms/*etiology
Neoplastic Stem Cells/*drug effects
Neoplastic Stem Cells/*metabolism
Proto-Oncogene Proteins c-mdm2/*antagonists & inhibitors
Proto-Oncogene Proteins c-mdm2/*metabolism
Animals ; Antineoplastic Agents/therapeutic use ; Biomarkers ; Cell Line, Tumor ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/pathology ; Disease Models, Animal ; Humans ; Hyaluronan Receptors/metabolism ; Mice ; Molecular Targeted Therapy ; Necrosis/pathology ; Protein Binding ; Tumor Suppressor Protein p53/pharmacology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Elevated plasma levels of galectin-3 binding protein are associated with post-stroke delirium - A pilot study.
Autorzy :
Klimiec-Moskal E; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Pasinska P; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Kowalska K; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Klimkowicz-Mrowiec A; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Pera J; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Slowik A; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland.
Dziedzic T; Department of Neurology, Jagiellonian University Medical College, Krakow, Poland. Electronic address: .
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Źródło :
Journal of neuroimmunology [J Neuroimmunol] 2021 Jul 15; Vol. 356, pp. 577579. Date of Electronic Publication: 2021 Apr 17.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Antigens, Neoplasm/*blood
Biomarkers, Tumor/*blood
Delirium/*blood
Delirium/*etiology
Stroke/*blood
Stroke/*complications
Aged ; Aged, 80 and over ; Biomarkers/blood ; Delirium/diagnosis ; Female ; Humans ; Male ; Pilot Projects ; Prospective Studies ; Stroke/diagnosis
Czasopismo naukowe
Tytuł :
PD-L1 as a biomarker of response to immune-checkpoint inhibitors.
Autorzy :
Doroshow DB; Center for Thoracic Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Bhalla S; Center for Thoracic Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Beasley MB; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sholl LM; Department of Pathology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.
Kerr KM; Department of Pathology, Aberdeen University School of Medicine and Aberdeen Royal Infirmary, Aberdeen, UK.
Gnjatic S; Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Wistuba II; Department of Translational Molecular Pathology, MD Anderson Cancer Center, Houston, TX, USA.
Rimm DL; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
Tsao MS; Department of Laboratory Medicine and Pathobiology, Princess Margaret Cancer Center, Toronto, ON, Canada.
Hirsch FR; Center for Thoracic Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .
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Źródło :
Nature reviews. Clinical oncology [Nat Rev Clin Oncol] 2021 Jun; Vol. 18 (6), pp. 345-362. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article; Review
MeSH Terms :
B7-H1 Antigen/*analysis
Biomarkers, Tumor/*analysis
Immune Checkpoint Inhibitors/*pharmacology
Neoplasms/*drug therapy
Biomarkers, Pharmacological/analysis ; Biopsy ; Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Immunohistochemistry ; Neoplasms/pathology ; Specimen Handling/methods ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Multivariable Prediction Model for Biochemical Response to First-Generation Somatostatin Receptor Ligands in Acromegaly.
Autorzy :
Coopmans EC; Department of Medicine, Endocrinology section, Pituitary Center Rotterdam, Erasmus University Medical Center, Rotterdam, the Netherlands.
Korevaar TIM; Department of Medicine, Endocrinology section, Pituitary Center Rotterdam, Erasmus University Medical Center, Rotterdam, the Netherlands.
van Meyel SWF; Department of Medicine, Endocrinology section, Pituitary Center Rotterdam, Erasmus University Medical Center, Rotterdam, the Netherlands.
Daly AF; Endocrinologie Centre Hospitalier Universitaire de Liège, Domaine Universitaire du Sart-Tilman, Liège, Belgium.
Chanson P; Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l'Hypophyse, Le Kremlin Bicêtre, France.; Université Paris-Saclay, Univ. Paris-Sud, Inserm, Signalisation Hormonale, Physiopathologie Endocrinienne et Métabolique, Le Kremlin-Bicêtre, France.
Brue T; Aix-Marseille Université, CNRS, Marseille, France.; APHM, Hôpital Conception, Service d'Endocrinologie, Diabète et Maladies Métaboliques, Centre de Référence des Maladies Rares d'Origine Hypophysaire, Marseille, France.
Delemer B; Department of Endocrinology, Diabetes, and Nutrition, University Hospital of Reims, Reims, France.
Hána V; 3rd Department of Internal Medicine, First Medical Faculty, Charles University, Prague, Czech Republic.
Colao A; Dipartimento di Medicina Clinica e Chirurgia, Università Federico II di Napoli, Naples, Italy.
Carvalho D; Department of Endocrinology, Diabetes and Metabolism Section and Instituto de Investigação e Inovação em Saúde, University of Porto, Centro Hospitalar S. João, Porto, Portugal.
Jaffrain-Rea ML; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila and Neuromed, IRCCS, Pozzilli, Italy.
Stalla GK; Clinical Neuroendocrinology, Max-Planck-Institute of Psychiatry, Munich, Germany.
Fajardo-Montañana C; Servicio de Endocrinología, Hospital Universitario La Ribera, Valencia, Spain.
Beckers A; Endocrinologie Centre Hospitalier Universitaire de Liège, Domaine Universitaire du Sart-Tilman, Liège, Belgium.
van der Lely AJ; Department of Medicine, Endocrinology section, Pituitary Center Rotterdam, Erasmus University Medical Center, Rotterdam, the Netherlands.
Petrossians P; Endocrinologie Centre Hospitalier Universitaire de Liège, Domaine Universitaire du Sart-Tilman, Liège, Belgium.
Neggers SJCMM; Department of Medicine, Endocrinology section, Pituitary Center Rotterdam, Erasmus University Medical Center, Rotterdam, the Netherlands.
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Źródło :
The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2020 Sep 01; Vol. 105 (9).
Typ publikacji :
Journal Article; Meta-Analysis; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Pharmacological*/analysis
Biomarkers, Pharmacological*/metabolism
Models, Theoretical*
Acromegaly/*drug therapy
Receptors, Somatostatin/*agonists
Somatostatin/*analogs & derivatives
Acromegaly/blood ; Acromegaly/diagnosis ; Adult ; Biomarkers/analysis ; Biomarkers/metabolism ; Cohort Studies ; Europe ; Female ; Human Growth Hormone/blood ; Humans ; Insulin-Like Growth Factor I/metabolism ; Ligands ; Male ; Middle Aged ; Multivariate Analysis ; Octreotide/therapeutic use ; Peptides, Cyclic/therapeutic use ; Prognosis ; Retrospective Studies ; Somatostatin/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Cancer Stem Cells-Origins and Biomarkers: Perspectives for Targeted Personalized Therapies.
Autorzy :
Walcher L; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.
Kistenmacher AK; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.
Suo H; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Kitte R; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.
Dluczek S; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.
Strauß A; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.
Blaudszun AR; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.
Yevsa T; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.
Fricke S; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.
Kossatz-Boehlert U; Department of Immunology, Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Aug 07; Vol. 11, pp. 1280. Date of Electronic Publication: 2020 Aug 07 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Biomarkers*
Neoplasms/*etiology
Neoplasms/*metabolism
Neoplastic Stem Cells/*metabolism
Animals ; Biomarkers, Tumor ; Cellular Senescence ; Combined Modality Therapy ; Disease Management ; Disease Progression ; Disease Susceptibility ; Drug Resistance, Neoplasm ; Humans ; Immunotherapy, Adoptive ; Molecular Diagnostic Techniques ; Molecular Targeted Therapy ; Neoplasms/diagnosis ; Neoplasms/therapy ; Neoplastic Stem Cells/drug effects ; Neoplastic Stem Cells/pathology ; Organ Specificity ; Precision Medicine/methods ; Prognosis
Czasopismo naukowe
Tytuł :
PIVKA-II serves as a potential biomarker that complements AFP for the diagnosis of hepatocellular carcinoma.
Autorzy :
Feng H; Department of Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Huanhuxi Road, Hexi District, Tianjin, 300060, China.
Li B; Department of Pharmacy, Tianjin Medical University Cancer Institute and Hospital, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Tianjin, China.
Li Z; Department of Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Huanhuxi Road, Hexi District, Tianjin, 300060, China.
Wei Q; Department of Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Huanhuxi Road, Hexi District, Tianjin, 300060, China.
Ren L; Department of Laboratory, Tianjin Medical University Cancer Institute and Hospital, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Huanhuxi Road, Hexi District, Tianjin, 300060, China. .
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Źródło :
BMC cancer [BMC Cancer] 2021 Apr 13; Vol. 21 (1), pp. 401. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor*
alpha-Fetoproteins*
Biomarkers/*blood
Carcinoma, Hepatocellular/*blood
Carcinoma, Hepatocellular/*diagnosis
Liver Neoplasms/*blood
Liver Neoplasms/*diagnosis
Protein Precursors/*blood
Carcinoma, Hepatocellular/therapy ; Disease Management ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Liquid Biopsy ; Liver Neoplasms/therapy ; Male ; Neoplasm Metastasis ; Neoplasm Staging ; Prognosis ; Prothrombin ; ROC Curve ; Reproducibility of Results ; Sensitivity and Specificity ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Predictive Biomarkers of Immune Checkpoint Inhibitors-Related Toxicities.
Autorzy :
Xu Y; Cancer Center, Renmin Hospital of Wuhan University, Wuhan, China.
Fu Y; Department of Oncology, Xiangyang Hospital, Hubei University of Chinese Medicine, Xiangyang, China.
Zhu B; Institute of Cancer, Xinqiao Hospital, Army Medical University, Chongqing, China.
Wang J; Department of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, China.
Zhang B; Cancer Center, Renmin Hospital of Wuhan University, Wuhan, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Oct 06; Vol. 11, pp. 2023. Date of Electronic Publication: 2020 Oct 06 (Print Publication: 2020).
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biomarkers*/blood
Antineoplastic Agents, Immunological/*adverse effects
Immune Checkpoint Inhibitors/*adverse effects
Molecular Targeted Therapy/*adverse effects
Neoplasms/*diagnosis
Neoplasms/*drug therapy
Animals ; Antineoplastic Agents, Immunological/administration & dosage ; Antineoplastic Agents, Immunological/therapeutic use ; Biomarkers, Tumor ; Humans ; Immune Checkpoint Inhibitors/administration & dosage ; Immune Checkpoint Inhibitors/therapeutic use ; Immune Checkpoint Proteins/genetics ; Liquid Biopsy ; Molecular Targeted Therapy/methods ; Neoplasms/etiology ; Neoplasms/mortality ; Organ Specificity ; Prognosis ; Tumor Microenvironment
Czasopismo naukowe
Tytuł :
Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma.
Autorzy :
Loeser H; Institute of Pathology, University Hospital Cologne, Germany.; Gastrointestinal Cancer Group Cologne, Department I for Internal Medicine, Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany.
Kraemer M; Institute of Pathology, University Hospital Cologne, Germany.
Gebauer F; Gastrointestinal Cancer Group Cologne, Department I for Internal Medicine, Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany.; Department of General, Visceral and Cancer Surgery, University Hospital Cologne, Germany.
Bruns C; Department of General, Visceral and Cancer Surgery, University Hospital Cologne, Germany.
Schröder W; Department of General, Visceral and Cancer Surgery, University Hospital Cologne, Germany.
Zander T; Gastrointestinal Cancer Group Cologne, Department I for Internal Medicine, Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology (CIO), University Hospital Cologne, Germany.
Alakus H; Gastrointestinal Cancer Group Cologne, Department I for Internal Medicine, Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany.; Department of General, Visceral and Cancer Surgery, University Hospital Cologne, Germany.
Hoelscher A; Center for Esophageal and Gastric Surgery, AGAPLESION Markus Krankenhaus, Frankfurt, Germany.
Buettner R; Institute of Pathology, University Hospital Cologne, Germany.
Lohneis P; Institute of Pathology, University Hospital Cologne, Germany.; Gastrointestinal Cancer Group Cologne, Department I for Internal Medicine, Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany.
Quaas A; Institute of Pathology, University Hospital Cologne, Germany.; Gastrointestinal Cancer Group Cologne, Department I for Internal Medicine, Center for Integrated Oncology, University Hospital of Cologne, Cologne, Germany.
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Źródło :
Journal of immunology research [J Immunol Res] 2020 Sep 22; Vol. 2020, pp. 2862647. Date of Electronic Publication: 2020 Sep 22 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor*
Gene Expression*
Adenocarcinoma/*genetics
Adenocarcinoma/*mortality
Esophageal Neoplasms/*genetics
Esophageal Neoplasms/*mortality
Indoleamine-Pyrrole 2,3,-Dioxygenase/*genetics
Adenocarcinoma/diagnosis ; Adenocarcinoma/therapy ; Aged ; Aged, 80 and over ; Biomarkers ; Esophageal Neoplasms/diagnosis ; Esophageal Neoplasms/therapy ; Female ; Humans ; Immunohistochemistry ; Male ; Middle Aged ; Neoadjuvant Therapy ; Neoplasm Metastasis ; Neoplasm Staging ; Prognosis ; Proportional Hazards Models
SCR Disease Name :
Adenocarcinoma Of Esophagus
Czasopismo naukowe
Tytuł :
Impact of RAS mutations on the immune infiltrate of colorectal liver metastases: A preliminary study.
Autorzy :
Polidoro MA; Hepatobiliary Immunopathology Laboratory, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.
Milana F; Department of Hepatobiliary and General Surgery, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.
Soldani C; Hepatobiliary Immunopathology Laboratory, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.
Franceschini B; Hepatobiliary Immunopathology Laboratory, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.
Anselmo A; Flow Cytometry Core, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.
Colombo FS; Flow Cytometry Core, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.
Di Tommaso L; Department of Pathology, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.; Department of Biomedical Science, Humanitas University, Rozzano, Milan, Italy.
Cimino M; Department of Hepatobiliary and General Surgery, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.
Carnevale S; Department of Biomedical Science, Humanitas University, Rozzano, Milan, Italy.
Lleo A; Hepatobiliary Immunopathology Laboratory, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.; Department of Biomedical Science, Humanitas University, Rozzano, Milan, Italy.; Department of Internal Medicine and Hepatology, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.
Jaillon S; Department of Biomedical Science, Humanitas University, Rozzano, Milan, Italy.
Torzilli G; Department of Hepatobiliary and General Surgery, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.; Department of Biomedical Science, Humanitas University, Rozzano, Milan, Italy.
Donadon M; Hepatobiliary Immunopathology Laboratory, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.; Department of Biomedical Science, Humanitas University, Rozzano, Milan, Italy.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2020 Aug; Vol. 108 (2), pp. 715-721. Date of Electronic Publication: 2020 Feb 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Tumor*
Mutation*
Colorectal Neoplasms/*genetics
Colorectal Neoplasms/*pathology
Liver Neoplasms/*immunology
Liver Neoplasms/*secondary
Proto-Oncogene Proteins p21(ras)/*genetics
Adult ; Aged ; Biomarkers ; Female ; Humans ; Immunohistochemistry ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Staging ; Prognosis ; Tumor Microenvironment/genetics ; Tumor Microenvironment/immunology
Czasopismo naukowe
Tytuł :
Molecular Characteristics of Lymphocyte-predominant Triple-negative Breast Cancer.
Autorzy :
Sasaki R; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Horimoto Y; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan; .; Department of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan.
Yanai Y; Department of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan.
Kurisaki-Arakawa A; Department of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan.
Arakawa A; Department of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan.
Nakai K; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Saito M; Department of Breast Oncology, Juntendo University School of Medicine, Tokyo, Japan.
Saito T; Department of Human Pathology, Juntendo University School of Medicine, Tokyo, Japan.
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Źródło :
Anticancer research [Anticancer Res] 2021 Apr; Vol. 41 (4), pp. 2133-2140.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor/*genetics
Lymphocytes, Tumor-Infiltrating/*metabolism
Triple Negative Breast Neoplasms/*diagnosis
Triple Negative Breast Neoplasms/*genetics
Adult ; Aged ; Aged, 80 and over ; B7-H1 Antigen/genetics ; B7-H1 Antigen/metabolism ; Biomarkers, Pharmacological/analysis ; Biomarkers, Pharmacological/metabolism ; Biomarkers, Tumor/analysis ; Biomarkers, Tumor/metabolism ; DNA Copy Number Variations ; DNA Mutational Analysis/methods ; Gene Expression Regulation, Neoplastic ; High-Throughput Nucleotide Sequencing ; Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Loss of Heterozygosity ; Lymphocyte Count ; Lymphocytes/metabolism ; Lymphocytes/pathology ; Lymphocytes, Tumor-Infiltrating/pathology ; Middle Aged ; Mutation ; PTEN Phosphohydrolase/genetics ; PTEN Phosphohydrolase/metabolism ; Polymorphism, Single Nucleotide ; Prognosis ; Transcriptome ; Treatment Outcome ; Triple Negative Breast Neoplasms/drug therapy ; Triple Negative Breast Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Multiomics Characterization of Low-Grade Serous Ovarian Carcinoma Identifies Potential Biomarkers of MEK Inhibitor Sensitivity and Therapeutic Vulnerability.
Autorzy :
Shrestha R; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.; Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Radiation Oncology, University of California San Francisco, San Francisco, California.
Llaurado Fernandez M; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada.
Dawson A; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada.
Hoenisch J; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada.
Volik S; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.
Lin YY; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.; Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Anderson S; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.
Kim H; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada.
Haegert AM; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.
Colborne S; Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.
Wong NKY; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Pathology & Laboratory Medicine, BC Cancer Agency, Vancouver, British Columbia, Canada.
McConeghy B; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.
Bell RH; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.
Brahmbhatt S; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.
Lee CH; Department of Pathology & Laboratory Medicine, BC Cancer Agency, Vancouver, British Columbia, Canada.
DiMattia GE; Translational Ovarian Cancer Research Program, London Health Science Centre, London, Ontario, Canada.
Le Bihan S; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.
Morin GB; Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
Collins CC; Vancouver Prostate Centre, Vancouver, British Columbia, Canada. .; Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Carey MS; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada. .
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Źródło :
Cancer research [Cancer Res] 2021 Apr 01; Vol. 81 (7), pp. 1681-1694. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biomarkers, Pharmacological/*analysis
Cystadenocarcinoma, Serous/*drug therapy
Mitogen-Activated Protein Kinase Kinases/*antagonists & inhibitors
Ovarian Neoplasms/*drug therapy
Protein Kinase Inhibitors/*therapeutic use
Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/isolation & purification ; Biomarkers, Tumor/metabolism ; Cell Line, Tumor ; Cohort Studies ; Cystadenocarcinoma, Serous/genetics ; Cystadenocarcinoma, Serous/metabolism ; Cystadenocarcinoma, Serous/pathology ; Drug Resistance, Neoplasm/genetics ; Female ; Genomics/methods ; Humans ; Metabolomics/methods ; Neoplasm Grading ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/metabolism ; Ovarian Neoplasms/pathology ; Proteomics/methods ; Systems Integration
Czasopismo naukowe
Tytuł :
Case Report: Long-Term Response to Pembrolizumab Combined With Endocrine Therapy in Metastatic Breast Cancer Patients With Hormone Receptor Expression.
Autorzy :
Wu D; Institute of Cancer, Xinqiao Hospital, Army Medical University, Chongqing, China.
Tang S; Institute of Cancer, Xinqiao Hospital, Army Medical University, Chongqing, China.
Ye R; Institute of Cancer, Xinqiao Hospital, Army Medical University, Chongqing, China.
Li D; Institute of Cancer, Xinqiao Hospital, Army Medical University, Chongqing, China.
Gu D; Geneplus-Beijing, Beijing, China.
Chen R; Geneplus-Beijing, Beijing, China.
Zhang H; Geneplus-Beijing, Beijing, China.
Sun J; Institute of Cancer, Xinqiao Hospital, Army Medical University, Chongqing, China.
Chen Z; Institute of Cancer, Xinqiao Hospital, Army Medical University, Chongqing, China.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Feb 22; Vol. 12, pp. 610149. Date of Electronic Publication: 2021 Feb 22 (Print Publication: 2021).
Typ publikacji :
Case Reports; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Biomarkers, Tumor/*metabolism
Breast Neoplasms/*drug therapy
Breast Neoplasms/*metabolism
Adult ; Antibodies, Monoclonal, Humanized/administration & dosage ; Antineoplastic Agents, Hormonal/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Biomarkers ; Breast Neoplasms/diagnosis ; Breast Neoplasms/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Immune Checkpoint Inhibitors/administration & dosage ; Immunohistochemistry ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Receptor, ErbB-2/metabolism ; Receptors, Estrogen/metabolism ; Receptors, Progesterone/metabolism ; Tomography, X-Ray Computed ; Treatment Outcome
Raport
Tytuł :
Banded tetra (Astyanax aeneus) as bioindicator of trace metals in aquatic ecosystems of the Yucatan Peninsula, Mexico: Experimental biomarkers validation and wild populations biomonitoring.
Autorzy :
Hinojosa-Garro D; Laboratorio en Ecología Acuática y Monitoreo Ambiental, CEDESU, Universidad Autónoma de Campeche, Av. Héroe de Nacozari No. 480, 24070, San Francisco de Campeche, Campeche, Mexico.
Osten JR; Instituto EPOMEX, Universidad Autónoma de Campeche, Av. Héroe de Nacozari No. 480, 24070, San Francisco de Campeche, Campeche, Mexico.
Dzul-Caamal R; Instituto EPOMEX, Universidad Autónoma de Campeche, Av. Héroe de Nacozari No. 480, 24070, San Francisco de Campeche, Campeche, Mexico. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Jun 01; Vol. 195, pp. 110477. Date of Electronic Publication: 2020 Mar 19.
Typ publikacji :
Journal Article
MeSH Terms :
Characiformes*/metabolism
Environmental Biomarkers*
Metals/*toxicity
Water Pollutants, Chemical/*toxicity
Acetylcholinesterase/metabolism ; Animals ; Biological Monitoring ; Biomarkers ; Catalase/metabolism ; Copper/toxicity ; Ecosystem ; Glutathione Transferase/metabolism ; Lipid Peroxidation/drug effects ; Metallothionein/metabolism ; Metals/analysis ; Mexico ; Muscles/drug effects ; Muscles/enzymology ; Muscles/metabolism ; Oxidative Stress ; Water Pollutants, Chemical/analysis
Czasopismo naukowe

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