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Wyszukujesz frazę ""Cell Lineage"" wg kryterium: Temat


Tytuł :
Lineage-specific control of convergent differentiation by a Forkhead repressor.
Autorzy :
Mizeracka K; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA 02115, USA.
Rogers JM; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Committee on Higher Degrees in Biophysics, Harvard University, Cambridge, MA 02138, USA.
Rumley JD; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Shaham S; The Rockefeller University, New York, NY 10065, USA.
Bulyk ML; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.; Committee on Higher Degrees in Biophysics, Harvard University, Cambridge, MA 02138, USA.; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Murray JI; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Heiman MG; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA 02115, USA.
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Źródło :
Development (Cambridge, England) [Development] 2021 Oct 01; Vol. 148 (19). Date of Electronic Publication: 2021 Sep 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cell Lineage*
Caenorhabditis elegans Proteins/*metabolism
Neuroglia/*metabolism
Transcription Factors/*metabolism
Animals ; Caenorhabditis elegans ; Caenorhabditis elegans Proteins/genetics ; Cell Differentiation ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; HEK293 Cells ; Humans ; Neuroglia/cytology ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Identification of a novel lineage bat SARS-related coronaviruses that use bat ACE2 receptor.
Autorzy :
Guo H; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Hu B; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.
Si HR; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Zhu Y; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.
Zhang W; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.
Li B; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.
Li A; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Geng R; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Lin HF; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Yang XL; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.
Zhou P; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.
Shi ZL; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan Institute of Virology, Wuhan, People's Republic of China.
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Źródło :
Emerging microbes & infections [Emerg Microbes Infect] 2021 Dec; Vol. 10 (1), pp. 1507-1514.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Lineage*
Angiotensin-Converting Enzyme 2/*physiology
Chiroptera/*virology
SARS Virus/*isolation & purification
SARS-CoV-2/*classification
Animals ; Host Specificity ; Phylogeny ; SARS Virus/classification
Czasopismo naukowe
Tytuł :
Phase 1 study of the histone deacetylase inhibitor entinostat plus clofarabine for poor-risk Philadelphia chromosome-negative (newly diagnosed older adults or adults with relapsed refractory disease) acute lymphoblastic leukemia or biphenotypic leukemia.
Autorzy :
Carraway HE; Hematology Oncology Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, United States. Electronic address: .
Sawalha Y; Arthur G. James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Gojo I; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital, Baltimore, MD, United States.
Lee MJ; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Lee S; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Tomita Y; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Yuno A; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Greer J; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital, Baltimore, MD, United States.
Smith BD; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital, Baltimore, MD, United States.
Pratz KW; The University of Pennsylvania, Philadelphia, Pennsylvania.
Levis MJ; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital, Baltimore, MD, United States.
Gore SD; Cancer Therapy Evaluation Program (CTEP), National Cancer Institute, NIH, Bethesda, MD, United States.
Ghosh N; Atrium Health, Carolinas HealthCare System, Charlotte, NC, United States.
Dezern A; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital, Baltimore, MD, United States.
Blackford AL; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital, Baltimore, MD, United States.
Baer MR; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD, United States.
Gore L; University of Colorado Cancer Center, Aurora, CO, United States.
Piekarz R; Cancer Therapy Evaluation Program (CTEP), National Cancer Institute, NIH, Bethesda, MD, United States.
Trepel JB; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States.
Karp JE; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital, Baltimore, MD, United States.
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Źródło :
Leukemia research [Leuk Res] 2021 Nov; Vol. 110, pp. 106707. Date of Electronic Publication: 2021 Sep 10.
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms :
Cell Lineage*
Drug Resistance, Neoplasm*
Philadelphia Chromosome*
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Neoplasm Recurrence, Local/*drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy
Adult ; Aged ; Benzamides/administration & dosage ; Clofarabine/administration & dosage ; Female ; Follow-Up Studies ; Histone Deacetylase Inhibitors/therapeutic use ; Humans ; Male ; Maximum Tolerated Dose ; Middle Aged ; Neoplasm Recurrence, Local/pathology ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Prognosis ; Pyridines/administration & dosage ; Salvage Therapy ; Young Adult
Czasopismo naukowe
Tytuł :
Evolution of irreversible somatic differentiation.
Autorzy :
Gao Y; Max Planck Institute for Evolutionary Biology, Plön, Germany.
Park HJ; Max Planck Institute for Evolutionary Biology, Plön, Germany.; Asia Pacific Center for Theoretical Physics, Pohang, Republic of Korea.; Department of Physics, POSTECH, Pohang, Republic of Korea.
Traulsen A; Max Planck Institute for Evolutionary Biology, Plön, Germany.
Pichugin Y; Max Planck Institute for Evolutionary Biology, Plön, Germany.
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Źródło :
ELife [Elife] 2021 Oct 13; Vol. 10. Date of Electronic Publication: 2021 Oct 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Evolution*
Cell Differentiation*
Cell Division*
Cell Lineage*
Models, Biological*
Germ Cells/*physiology
Animals ; Gene Expression Regulation ; Phenotype
Czasopismo naukowe
Tytuł :
Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects.
Autorzy :
Galgoczi S; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.
Ruzo A; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.
Markopoulos C; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.
Yoney A; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.; Laboratory of condensed matter physics, The Rockefeller University, New York, NY 10065, USA.
Phan-Everson T; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.; Laboratory of condensed matter physics, The Rockefeller University, New York, NY 10065, USA.
Li S; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.
Haremaki T; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.
Metzger JJ; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.; Laboratory of condensed matter physics, The Rockefeller University, New York, NY 10065, USA.
Etoc F; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.; Laboratory of condensed matter physics, The Rockefeller University, New York, NY 10065, USA.
Brivanlou AH; Laboratory of Stem Cell Biology and Molecular Embryology, The Rockefeller University, New York, NY 10065, USA.
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Źródło :
Development (Cambridge, England) [Development] 2021 Oct 01; Vol. 148 (19). Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Lineage*
Cell Polarity*
Germ Layers/*metabolism
Human Embryonic Stem Cells/*metabolism
Huntingtin Protein/*metabolism
Activins/metabolism ; Animals ; Cell Line ; Cells, Cultured ; Epithelial Cells/cytology ; Epithelial Cells/metabolism ; Germ Layers/cytology ; Germ Layers/embryology ; Human Embryonic Stem Cells/cytology ; Humans ; Huntingtin Protein/genetics ; Mice ; Signal Transduction ; Transforming Growth Factor beta/metabolism ; Trinucleotide Repeat Expansion
Czasopismo naukowe
Tytuł :
microRNA-mediated regulation of microRNA machinery controls cell fate decisions.
Autorzy :
Liu Q; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, United States.
Novak MK; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, United States.
Pepin RM; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, United States.
Eich T; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, United States.
Hu W; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, United States.
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Źródło :
ELife [Elife] 2021 Oct 01; Vol. 10. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Cell Lineage*
MicroRNAs/*metabolism
Mouse Embryonic Stem Cells/*metabolism
Animals ; Argonaute Proteins/genetics ; Argonaute Proteins/metabolism ; Cell Line ; Cell Proliferation ; Cell Self Renewal ; Gene Expression Regulation, Developmental ; Mice ; MicroRNAs/genetics ; Transcription Factors/genetics ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Deciphering two rounds of cell lineage segregations during bovine preimplantation development.
Autorzy :
Akizawa H; Laboratory of Animal Genetics and Reproduction, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Saito S; Laboratory of Animal Genetics and Reproduction, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Kohri N; Laboratory of Animal Genetics and Reproduction, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Furukawa E; Laboratory of Theriogenology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Hayashi Y; Laboratory of Animal Genetics and Reproduction, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Bai H; Laboratory of Animal Genetics and Reproduction, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Nagano M; Laboratory of Animal Reproduction, Department of Animal Science, School of Veterinary Medicine, Kitasato University, Towada, Japan.
Yanagawa Y; Laboratory of Theriogenology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Tsukahara H; Laboratory of Animal Genetics and Reproduction, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Takahashi M; Global Station for Food, Land and Water Resources, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido, Japan.
Kagawa S; Livestock Research Institute, Aomori Prefectural Industrial Technology Research Center, Aomori, Japan.
Kawahara-Miki R; NODAI Genome Research Center, Tokyo University of Agriculture, Setagaya, Japan.
Kobayashi H; Department of Embryology, Nara Medical University, Kashihara, Japan.
Kono T; Department of Bioscience, Tokyo University of Agriculture, Setagaya, Japan.
Kawahara M; Laboratory of Animal Genetics and Reproduction, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Oct; Vol. 35 (10), pp. e21904.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Lineage*
Embryonic Development*
Gene Expression Regulation, Developmental*
Antigens, Differentiation/*biosynthesis
Blastocyst/*metabolism
Animals ; Cattle
Czasopismo naukowe
Tytuł :
Cellular origins and lineage relationships of the intestinal epithelium.
Autorzy :
Capdevila C; Columbia Stem Cell Initiative, Division of Digestive and Liver Diseases, Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, New York.; Department of Genetics & Development, Columbia University Irving Medical Center, New York, New York.
Trifas M; Columbia Stem Cell Initiative, Division of Digestive and Liver Diseases, Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, New York.; Department of Genetics & Development, Columbia University Irving Medical Center, New York, New York.
Miller J; Columbia Stem Cell Initiative, Division of Digestive and Liver Diseases, Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, New York.; Department of Genetics & Development, Columbia University Irving Medical Center, New York, New York.
Anderson T; Columbia Stem Cell Initiative, Division of Digestive and Liver Diseases, Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, New York.; Department of Genetics & Development, Columbia University Irving Medical Center, New York, New York.
Sims PA; Department of Systems Biology, Columbia University Irving Medical Center, New York, New York.; Department of Biochemistry & Molecular Biophysics, Columbia University Irving Medical Center, New York, New York.
Yan KS; Columbia Stem Cell Initiative, Division of Digestive and Liver Diseases, Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, New York.; Department of Genetics & Development, Columbia University Irving Medical Center, New York, New York.
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Źródło :
American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2021 Oct 01; Vol. 321 (4), pp. G413-G425. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cell Lineage*
Intestinal Mucosa/*cytology
Animals ; Humans ; Intestinal Mucosa/metabolism ; RNA-Seq ; Single-Cell Analysis ; Transcriptome
Czasopismo naukowe
Tytuł :
Sequential actions of EOMES and T-BET promote stepwise maturation of natural killer cells.
Autorzy :
Zhang J; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.; Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, China.
Le Gras S; IGBMC, CNRS UMR7104, Inserm U1258, Université de Strasbourg, Illkirch, France.; Plateforme GenomEast, infrastructure France Génomique, Illkirch, France.
Pouxvielh K; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.
Faure F; Institut NeuroMyoGène, INSERM U1217/CNRS UMR5310, Université de Lyon, Université Claude Bernard, Lyon 1, Lyon, France.
Fallone L; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.
Kern N; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.
Moreews M; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.
Mathieu AL; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.
Schneider R; Institut de Génomique Fonctionnelle de Lyon, CNRS UMR 5242, Ecole Normale Supérieure de Lyon Université Claude Bernard Lyon 1, 46 allée d'Italie, F-69364, Lyon, France.
Marliac Q; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.
Jung M; IGBMC, CNRS UMR7104, Inserm U1258, Université de Strasbourg, Illkirch, France.; Plateforme GenomEast, infrastructure France Génomique, Illkirch, France.
Berton A; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.
Hayek S; Equipe Chimie et Biologie, Modélisation et Immunologie pour la Thérapie (CBMIT), Université Paris Descartes, CNRS UMR 8601, 75006, Paris, France.
Vidalain PO; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.; Equipe Chimie et Biologie, Modélisation et Immunologie pour la Thérapie (CBMIT), Université Paris Descartes, CNRS UMR 8601, 75006, Paris, France.
Marçais A; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.
Dodard G; Department of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University Alpert Medical School, Providence, RI, 02912, USA.
Dejean A; Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), INSERM UMR1291 - CNRS UMR5051 - Université Toulouse III, Toulouse, France.
Brossay L; Department of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University Alpert Medical School, Providence, RI, 02912, USA.
Ghavi-Helm Y; Institut de Génomique Fonctionnelle de Lyon, CNRS UMR 5242, Ecole Normale Supérieure de Lyon Université Claude Bernard Lyon 1, 46 allée d'Italie, F-69364, Lyon, France.
Walzer T; CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 14; Vol. 12 (1), pp. 5446. Date of Electronic Publication: 2021 Sep 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Cycle/*genetics
Cell Lineage/*genetics
Killer Cells, Natural/*immunology
T-Box Domain Proteins/*genetics
Animals ; Base Sequence ; Bone Marrow Cells/cytology ; Bone Marrow Cells/immunology ; CD11b Antigen/genetics ; CD11b Antigen/immunology ; Cell Cycle/drug effects ; Cell Cycle/immunology ; Cell Differentiation ; Cell Lineage/drug effects ; Cell Lineage/immunology ; Epigenesis, Genetic/immunology ; Interleukin-12/pharmacology ; Killer Cells, Natural/cytology ; Killer Cells, Natural/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Promoter Regions, Genetic ; Protein Binding ; Spleen/cytology ; Spleen/immunology ; T-Box Domain Proteins/deficiency ; T-Box Domain Proteins/immunology ; Transcription, Genetic ; Tumor Necrosis Factor Receptor Superfamily, Member 7/genetics ; Tumor Necrosis Factor Receptor Superfamily, Member 7/immunology
Czasopismo naukowe
Tytuł :
The role of cell lineage in the development of neuronal circuitry and function.
Autorzy :
Hartenstein V; Department of Molecular Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, 90095, USA. Electronic address: .
Omoto JJ; Department of Molecular Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, 90095, USA.
Lovick JK; Department of Molecular Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, 90095, USA.
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Źródło :
Developmental biology [Dev Biol] 2021 Jul; Vol. 475, pp. 165-180. Date of Electronic Publication: 2020 Feb 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Cell Lineage/*physiology
Nerve Net/*cytology
Neurons/*cytology
Animals ; Brain/cytology ; Cell Differentiation ; Cell Lineage/genetics ; Cerebral Cortex/cytology ; Gene Expression Regulation, Developmental ; Humans ; Nerve Net/metabolism ; Nerve Net/physiology ; Nervous System/cytology ; Neurons/metabolism ; Neurons/physiology ; Stem Cells/cytology
Czasopismo naukowe
Tytuł :
Human embryo polarization requires PLC signaling to mediate trophectoderm specification.
Autorzy :
Zhu M; Mammalian Embryo and Stem Cell Group, University of Cambridge, Department of Physiology, Development and Neuroscience, Cambridge, United Kingdom.; Blavatnik Institute, Harvard Medical School, Department of Genetics, Boston, United States.
Shahbazi M; Mammalian Embryo and Stem Cell Group, University of Cambridge, Department of Physiology, Development and Neuroscience, Cambridge, United Kingdom.; MRC Laboratory of Molecular Biology. Francis Crick Avenue, Biomedical Campus., Cambridge, United Kingdom.
Martin A; IVIRMA Valencia, IVI Foundation, Valencia, Spain.
Zhang C; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, China.; Key laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, China.
Sozen B; Developmental Plasticity and Self-Organization Group, California Institute of Technology, Division of Biology and Biological Engineering, Pasadena, United States.; Yale School of Medicine, Department of Genetics, New Haven, CT, United States.
Borsos M; California Institute of Technology, Division of Biology and Biological Engineering,, Pasadena, United States.
Mandelbaum RS; USC Fertility, University of Southern California, Keck School of Medicine, Los Angeles, United Kingdom.
Paulson RJ; USC Fertility, University of Southern California, Keck School of Medicine, Los Angeles, United Kingdom.
Mole MA; Mammalian Embryo and Stem Cell Group, University of Cambridge, Department of Physiology, Development and Neuroscience, Cambridge, United Kingdom.
Esbert M; IVIRMA New Jersey, Basking Ridge, NJ, United States.
Titus S; IVIRMA New Jersey, Basking Ridge, NJ, United States.
Scott RT; IVIRMA New Jersey, Basking Ridge, NJ, United States.
Campbell A; CARE Fertility Group, John Webster House, 6 Lawrence Drive, Nottingham Business Park, Nottingham, United Kingdom.
Fishel S; CARE Fertility Group, John Webster House, 6 Lawrence Drive, Nottingham Business Park, Nottingham, United Kingdom.; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, United Kingdom.
Gradinaru V; MRC Laboratory of Molecular Biology. Francis Crick Avenue, Biomedical Campus., Cambridge, United Kingdom.
Zhao H; Key laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, China.
Wu K; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, China.; Key laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, China.
Chen ZJ; Center for Reproductive Medicine, Cheeloo College of Medicine, Shandong University, Jinan, China.; Key laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, China.
Seli E; IVIRMA New Jersey, Basking Ridge, NJ, United States.; Yale School of Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, New Haven, CT, United States.
de Los Santos MJ; IVIRMA Valencia, IVI Foundation, Valencia, Spain.
Zernicka Goetz M; Mammalian Embryo and Stem Cell Group, University of Cambridge, Department of Physiology, Development and Neuroscience, Cambridge, United Kingdom.; Developmental Plasticity and Self-Organization Group, California Institute of Technology, Division of Biology and Biological Engineering, Pasadena, United States.
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Źródło :
ELife [Elife] 2021 Sep 27; Vol. 10. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Body Patterning*
Cell Differentiation*
Cell Lineage*
Cell Polarity*
Embryo, Mammalian/*enzymology
Actins/metabolism ; Adult ; Embryo Culture Techniques ; Female ; GATA3 Transcription Factor/metabolism ; Gene Expression Regulation, Developmental ; Gene Expression Regulation, Enzymologic ; Humans ; Phosphoinositide Phospholipase C ; Phospholipase C beta ; Pregnancy ; Signal Transduction ; Time Factors ; Young Adult
Czasopismo naukowe
Tytuł :
Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity.
Autorzy :
Wang J; Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.
Farkas C; Department of Pharmacology and Therapeutics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.; CancerCare Manitoba Research Institute, Winnipeg, Manitoba, Canada.
Benyoucef A; Department of Pharmacology and Therapeutics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.; CancerCare Manitoba Research Institute, Winnipeg, Manitoba, Canada.
Carmichael C; Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.
Haigh K; Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.; Department of Pharmacology and Therapeutics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.; CancerCare Manitoba Research Institute, Winnipeg, Manitoba, Canada.
Wong N; Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.
Huylebroeck D; Department of Cell Biology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
Stemmler MP; Department of Experimental Medicine 1, Nikolaus-Fiebiger-Centre for Molecular Medicine, FAU University Erlangen-Nürnberg, Erlangen, Germany.
Brabletz S; Department of Experimental Medicine 1, Nikolaus-Fiebiger-Centre for Molecular Medicine, FAU University Erlangen-Nürnberg, Erlangen, Germany.
Brabletz T; Department of Experimental Medicine 1, Nikolaus-Fiebiger-Centre for Molecular Medicine, FAU University Erlangen-Nürnberg, Erlangen, Germany.
Nefzger CM; Department of Anatomy and Developmental Biology, Monash University, Melbourne, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, Australia.
Goossens S; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University, Ghent, Belgium.; Department of Diagnostic Sciences, Ghent University and University Hospital, Ghent, Belgium.
Berx G; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University, Ghent, Belgium.
Polo JM; Department of Experimental Medicine 1, Nikolaus-Fiebiger-Centre for Molecular Medicine, FAU University Erlangen-Nürnberg, Erlangen, Germany.; Department of Anatomy and Developmental Biology, Monash University, Melbourne, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, Australia.
Haigh JJ; Australian Centre for Blood Diseases, Monash University, Melbourne, Australia.; Department of Pharmacology and Therapeutics, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.; CancerCare Manitoba Research Institute, Winnipeg, Manitoba, Canada.
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Źródło :
PLoS biology [PLoS Biol] 2021 Sep 22; Vol. 19 (9), pp. e3001394. Date of Electronic Publication: 2021 Sep 22 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Lineage*
Hematopoietic Stem Cells/*metabolism
Leukemia, Myeloid, Acute/*metabolism
Zinc Finger E-box Binding Homeobox 2/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
Animals ; Bone Marrow Cells/pathology ; Cell Differentiation ; Gene Expression Regulation, Neoplastic ; Hematopoiesis ; Hematopoietic Stem Cells/pathology ; Leukemia, Myeloid, Acute/pathology ; Mice ; Mice, Transgenic ; RNA-Seq ; Zinc Finger E-box Binding Homeobox 2/genetics ; Zinc Finger E-box-Binding Homeobox 1/genetics
Czasopismo naukowe
Tytuł :
Lymph Node Stromal Cell-Intrinsic MHC Class II Expression Promotes MHC Class I-Restricted CD8 T Cell Lineage Conversion to Regulatory CD4 T Cells.
Autorzy :
Honan AM; Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL; and.
Vazquez EN; Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL; and.
Chen Z; Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL; and .; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Sep 15; Vol. 207 (6), pp. 1530-1544. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
CD8-Positive T-Lymphocytes/*immunology
Cell Lineage/*genetics
Colitis/*immunology
Histocompatibility Antigens Class I/*metabolism
Histocompatibility Antigens Class II/*metabolism
Lymph Nodes/*immunology
Signal Transduction/*genetics
Stromal Cells/*immunology
T-Lymphocytes, Regulatory/*immunology
Adoptive Transfer/methods ; Animals ; Antigen-Presenting Cells/immunology ; Cell Lineage/immunology ; Cells, Cultured ; Disease Models, Animal ; Female ; Histocompatibility Antigens Class II/genetics ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe
Tytuł :
Tissue of Origin, but Not XCI State, Influences Germ Cell Differentiation from Human Pluripotent Stem Cells.
Autorzy :
Chang YW; Department of Anatomy and Embryology, Leiden University Medical Centre, 2333 ZC Leiden, The Netherlands.
Overeem AW; Department of Anatomy and Embryology, Leiden University Medical Centre, 2333 ZC Leiden, The Netherlands.
Roelse CM; Department of Anatomy and Embryology, Leiden University Medical Centre, 2333 ZC Leiden, The Netherlands.
Fan X; Department of Anatomy and Embryology, Leiden University Medical Centre, 2333 ZC Leiden, The Netherlands.
Freund C; Department of Anatomy and Embryology, Leiden University Medical Centre, 2333 ZC Leiden, The Netherlands.; Leiden University Medical Center hiPSC Hotel, Leiden University Medical Centre, 2333 ZC Leiden, The Netherlands.
Chuva de Sousa Lopes SM; Department of Anatomy and Embryology, Leiden University Medical Centre, 2333 ZC Leiden, The Netherlands.; Ghent-Fertility and Stem Cell Team (G-FAST), Department of Reproductive Medicine, Ghent University Hospital, 9000 Ghent, Belgium.
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Źródło :
Cells [Cells] 2021 Sep 13; Vol. 10 (9). Date of Electronic Publication: 2021 Sep 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Cell Lineage*
X Chromosome Inactivation*
Embryoid Bodies/*cytology
Kidney/*cytology
Pluripotent Stem Cells/*cytology
Skin/*cytology
Embryoid Bodies/metabolism ; Female ; Fibroblasts/cytology ; Fibroblasts/metabolism ; Germ Cells/cytology ; Germ Cells/metabolism ; Humans ; Kidney/metabolism ; Male ; Pluripotent Stem Cells/metabolism ; Skin/metabolism
Czasopismo naukowe
Tytuł :
Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes.
Autorzy :
Brenes AJ; Centre for Gene Regulation and Expression, University of Dundee, Dundee, United Kingdom.; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Vandereyken M; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, United Kingdom.
James OJ; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, United Kingdom.
Watt H; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, United Kingdom.
Hukelmann J; Centre for Gene Regulation and Expression, University of Dundee, Dundee, United Kingdom.
Spinelli L; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Dikovskaya D; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, United Kingdom.
Lamond AI; Centre for Gene Regulation and Expression, University of Dundee, Dundee, United Kingdom.
Swamy M; Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, United Kingdom.; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, United Kingdom.
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Źródło :
ELife [Elife] 2021 Sep 02; Vol. 10. Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Lineage*
Cellular Microenvironment*
Lymphocyte Activation*
Proteome*
Proteomics*
Intestinal Mucosa/*metabolism
Intraepithelial Lymphocytes/*metabolism
Animals ; Biomarkers/metabolism ; Chromatography, High Pressure Liquid ; Homeostasis ; Intestinal Mucosa/immunology ; Intraepithelial Lymphocytes/immunology ; Male ; Mice, Inbred C57BL ; Phenotype ; Signal Transduction ; Spectrometry, Mass, Electrospray Ionization ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Conservation lost: host-pathogen battles drive diversification and expansion of gene families.
Autorzy :
Lažetić V; Division of Biological Sciences, University of California, San Diego, La Jolla, CA, USA.
Troemel ER; Division of Biological Sciences, University of California, San Diego, La Jolla, CA, USA.
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Źródło :
The FEBS journal [FEBS J] 2021 Sep; Vol. 288 (18), pp. 5289-5299. Date of Electronic Publication: 2020 Dec 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cell Lineage/*genetics
Host-Parasite Interactions/*genetics
Immune System/*immunology
Multigene Family/*genetics
Cell Lineage/immunology ; Conserved Sequence/genetics ; Host-Parasite Interactions/immunology ; Humans ; Multigene Family/immunology ; Signal Transduction/genetics ; Species Specificity ; Virulence Factors/genetics ; Virulence Factors/immunology
Czasopismo naukowe
Tytuł :
Immunohistochemical analysis of the expression of selected cell lineage markers (CD4, CD8, CD68, c-Kit, Foxp3, CD56, CD20) in cutaneous variant of lichen planus.
Autorzy :
Żychowska M; Department of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, Poland.; Department of Dermatology, Venereology and Allergology, Wrocław Medical University, Wrocław, Poland.
Woźniak Z; Department of Pathomorphology, Wrocław Medical University, Wrocław, Poland.
Baran W; Department of Dermatology, Venereology and Allergology, Wrocław Medical University, Wrocław, Poland.
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Źródło :
International journal of dermatology [Int J Dermatol] 2021 Sep; Vol. 60 (9), pp. 1097-1101. Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Lineage*
Lichen Planus*
Skin Diseases*
Antigens, CD ; Antigens, CD20 ; Antigens, Differentiation, Myelomonocytic ; CD4-CD8 Ratio ; CD56 Antigen ; Forkhead Transcription Factors ; Humans ; Proto-Oncogene Proteins c-kit ; Skin
Czasopismo naukowe
Tytuł :
Ribosome-Induced Cellular Multipotency, an Emerging Avenue in Cell Fate Reversal.
Autorzy :
Istiaq A; Department of Stem Cell Biology, Faculty of Arts and Science, Kyushu University, Fukuoka 819-0395, Japan.; Department of Brain Morphogenesis, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-8555, Japan.; HIGO Program, Kumamoto University, Kumamoto 860-8555, Japan.
Ohta K; Department of Stem Cell Biology, Faculty of Arts and Science, Kyushu University, Fukuoka 819-0395, Japan.
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Źródło :
Cells [Cells] 2021 Sep 01; Vol. 10 (9). Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cell Lineage*
Protein Biosynthesis*
Germ Layers/*cytology
Neoplasms/*pathology
RNA, Messenger/*metabolism
Ribosomal Proteins/*metabolism
Ribosomes/*physiology
Animals ; Cell Differentiation ; Germ Layers/metabolism ; Humans ; Neoplasms/genetics ; Neoplasms/metabolism ; RNA, Messenger/genetics ; Ribosomal Proteins/genetics
Czasopismo naukowe
Tytuł :
Nkx2-2 expressing taste cells in endoderm-derived taste papillae are committed to the type III lineage.
Autorzy :
Qin Y; School of Food Science and Bioengineering, Zhejiang Gongshang University, Hangzhou, PR China; Monell Chemical Senses Center, Philadelphia, PA, USA.
Sukumaran SK; Monell Chemical Senses Center, Philadelphia, PA, USA; Present Address: Department of Nutrition and Health Sciences, University of Nebraska- Lincoln, Lincoln, NE, USA. Electronic address: .
Margolskee RF; Monell Chemical Senses Center, Philadelphia, PA, USA.
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Źródło :
Developmental biology [Dev Biol] 2021 Sep; Vol. 477, pp. 232-240. Date of Electronic Publication: 2021 Jun 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Lineage/*physiology
Homeodomain Proteins/*physiology
Taste Buds/*embryology
Zebrafish Proteins/*physiology
Animals ; Animals, Newborn ; Antigens, Differentiation/biosynthesis ; Antigens, Differentiation/physiology ; Cell Count ; Cell Lineage/genetics ; Female ; Homeodomain Proteins/biosynthesis ; Male ; Mice ; RNA-Seq ; Taste Buds/cytology ; Taste Buds/metabolism ; Zebrafish Proteins/biosynthesis
Czasopismo naukowe
Tytuł :
Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.
Autorzy :
Willnow D; Centre for Stem Cells and Regenerative Medicine, King's College London, London, UK.; Berlin Institute of Health, Berlin, Germany.
Benary U; Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany.
Margineanu A; Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany.
Vignola ML; Centre for Stem Cells and Regenerative Medicine, King's College London, London, UK.
Konrath F; Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany.
Pongrac IM; Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany.
Karimaddini Z; Department of Biosystems Science and Engineering (D-BSSE), ETH Zurich, Basel, Switzerland.; Swiss Institute of Bioinformatics, Basel, Switzerland.
Vigilante A; Centre for Stem Cells and Regenerative Medicine, King's College London, London, UK.
Wolf J; Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany.; Department of Mathematics and Computer Science, Free University, Berlin, Germany.
Spagnoli FM; Centre for Stem Cells and Regenerative Medicine, King's College London, London, UK. .
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Źródło :
Nature [Nature] 2021 Sep; Vol. 597 (7874), pp. 87-91. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Lineage*/genetics
Stem Cell Niche*/genetics
Biliary Tract/*cytology
Liver/*cytology
Pancreas/*cytology
Animals ; Biliary Tract/embryology ; Biliary Tract/metabolism ; Cell Tracking ; Embryo, Mammalian/cytology ; Embryo, Mammalian/metabolism ; Female ; Liver/embryology ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Models, Biological ; Pancreas/embryology ; Pancreas/metabolism ; RNA-Seq ; Signal Transduction ; Single-Cell Analysis
Czasopismo naukowe

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