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Wyszukujesz frazę ""Disease Progression"" wg kryterium: Temat


Tytuł :
A time-resolved proteomic and prognostic map of COVID-19.
Autorzy :
Demichev V; Charité Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK; The University of Cambridge, Department of Biochemistry and Cambridge Centre for Proteomics, Cambridge CB21GA, UK.
Tober-Lau P; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Lemke O; Charité Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany.
Nazarenko T; University College London, Department of Mathematics, London WC1E 6BT, UK; University College London, Department of Women's Cancer, EGA Institute for Women'S Health, London WC1E 6BT, UK.
Thibeault C; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Whitwell H; National Phenome Centre and Imperial Clinical Phenotyping Centre, Department of Metabolism, Digestion and Reproduction, Imperial College London, London SW72AZ, UK; Lobachevsky University, Department of Applied Mathematics, Nizhny Novgorod 603105, Russia; Imperial College London, Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, London SW7 2AZ, UK.
Röhl A; Charité Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany.
Freiwald A; Charité Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany.
Szyrwiel L; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK.
Ludwig D; Charité Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany.
Correia-Melo C; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK.
Aulakh SK; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK.
Helbig ET; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Stubbemann P; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Lippert LJ; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Grüning NM; Charité Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany.
Blyuss O; Lobachevsky University, Department of Applied Mathematics, Nizhny Novgorod 603105, Russia; University of Hertfordshire, School of Physics, Astronomy and Mathematics, Hatfield AL10 9AB, UK; Sechenov First Moscow State Medical University, Department of Paediatrics and Paediatric Infectious Diseases, Moscow 119435, Russia.
Vernardis S; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK.
White M; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK.
Messner CB; Charité Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK.
Joannidis M; Medical University Innsbruck, Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, 6020 Innsbruck, Austria.
Sonnweber T; Medical University of Innsbruck, Department of Internal Medicine II, 6020 Innsbruck, Austria.
Klein SJ; Medical University Innsbruck, Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, 6020 Innsbruck, Austria.
Pizzini A; Medical University of Innsbruck, Department of Internal Medicine II, 6020 Innsbruck, Austria.
Wohlfarter Y; Medical University of Innsbruck, Institute of Human Genetics, 6020 Innsbruck, Austria.
Sahanic S; Medical University of Innsbruck, Department of Internal Medicine II, 6020 Innsbruck, Austria.
Hilbe R; Medical University of Innsbruck, Department of Internal Medicine II, 6020 Innsbruck, Austria.
Schaefer B; Medical University of Innsbruck, Christian Doppler Laboratory for Iron and Phosphate Biology, Department of Internal Medicine I, 6020 Innsbruck, Austria.
Wagner S; Medical University of Innsbruck, Christian Doppler Laboratory for Iron and Phosphate Biology, Department of Internal Medicine I, 6020 Innsbruck, Austria.
Mittermaier M; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany; Berlin Institute of Health, 10178 Berlin, Germany.
Machleidt F; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Garcia C; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Ruwwe-Glösenkamp C; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Lingscheid T; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Bosquillon de Jarcy L; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Stegemann MS; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Pfeiffer M; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Jürgens L; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Denker S; Charité Universitätsmedizin Berlin, Medical Department of Hematology, Oncology & Tumor Immunology, Virchow Campus & Molekulares Krebsforschungszentrum, 13353 Berlin, Germany; Berlin Institute of Health, 10178 Berlin, Germany.
Zickler D; Charité Universitätsmedizin Berlin, Department of Nephrology and Internal Intensive Care Medicine, 10117 Berlin, Germany.
Enghard P; Charité Universitätsmedizin Berlin, Department of Nephrology and Internal Intensive Care Medicine, 10117 Berlin, Germany.
Zelezniak A; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK; Chalmers Tekniska Högskola, Department of Biology and Biological Engineering, SE-412 96 Gothenburg, Sweden.
Campbell A; University of Edinburgh, Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, Edinburgh EH4 2XU, UK; University of Edinburgh, Usher Institute, Edinburgh EH16 4UX, UK.
Hayward C; University of Edinburgh, MRC Human Genetics Unit, Institute of Genetics and Cancer, Edinburgh EH4 2XU, UK.
Porteous DJ; University of Edinburgh, Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, Edinburgh EH4 2XU, UK; University of Edinburgh, Usher Institute, Edinburgh EH16 4UX, UK.
Marioni RE; University of Edinburgh, Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, Edinburgh EH4 2XU, UK.
Uhrig A; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Müller-Redetzky H; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany.
Zoller H; Medical University of Innsbruck, Christian Doppler Laboratory for Iron and Phosphate Biology, Department of Internal Medicine I, 6020 Innsbruck, Austria.
Löffler-Ragg J; Medical University of Innsbruck, Department of Internal Medicine II, 6020 Innsbruck, Austria.
Keller MA; Medical University of Innsbruck, Institute of Human Genetics, 6020 Innsbruck, Austria.
Tancevski I; Medical University of Innsbruck, Department of Internal Medicine II, 6020 Innsbruck, Austria.
Timms JF; University College London, Department of Women's Cancer, EGA Institute for Women'S Health, London WC1E 6BT, UK.
Zaikin A; University College London, Department of Mathematics, London WC1E 6BT, UK; University College London, Department of Women's Cancer, EGA Institute for Women'S Health, London WC1E 6BT, UK; Lobachevsky University, Laboratory of Systems Medicine of Healthy Ageing, Nizhny Novgorod 603105, Russia.
Hippenstiel S; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany; German Centre for Lung Research, 35392 Gießen, Germany.
Ramharter M; Bernhard Nocht Institute for Tropical Medicine, Department of Tropical Medicine, and University Medical Center Hamburg-Eppendorf, Department of Medicine, 20359 Hamburg, Germany.
Witzenrath M; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany; German Centre for Lung Research, 35392 Gießen, Germany.
Suttorp N; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany; German Centre for Lung Research, 35392 Gießen, Germany.
Lilley K; The University of Cambridge, Department of Biochemistry and Cambridge Centre for Proteomics, Cambridge CB21GA, UK.
Mülleder M; Charité - Universitätsmedizin Berlin, Core Facility - High-Throughput Mass Spectrometry, 10117 Berlin, Germany.
Sander LE; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany; German Centre for Lung Research, 35392 Gießen, Germany.
Ralser M; Charité Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK. Electronic address: .
Kurth F; Charité Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, 10117 Berlin, Germany; Bernhard Nocht Institute for Tropical Medicine, Department of Tropical Medicine, and University Medical Center Hamburg-Eppendorf, Department of Medicine, 20359 Hamburg, Germany.
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Corporate Authors :
PA-COVID-19 Study group
Źródło :
Cell systems [Cell Syst] 2021 Aug 18; Vol. 12 (8), pp. 780-794.e7. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Progression*
Biomarkers/*analysis
COVID-19/*pathology
Proteome/*physiology
Age Factors ; Blood Cell Count ; Blood Gas Analysis ; Enzyme Activation ; Humans ; Inflammation/pathology ; Machine Learning ; Prognosis ; Proteomics ; SARS-CoV-2/immunology
Czasopismo naukowe
Tytuł :
Progression of Clinical Features in Lewy Body Dementia Can Be Detected Over 6 Months.
Autorzy :
Matar E; From the Department of Psychiatry (E.M., S.R.W., A.S., J.T.O.) and MRC Biostatistics Unit (S.R.W.), University of Cambridge, UK; Forefront Parkinson's Disease Research Clinic (E.M., G.M.H., S.J.G.L.) and Brain and Mind Centre (E.M., G.M.H., S.J.G.L.), Faculty of Medicine and Health, University of Sydney, Australia; Newcastle Translational and Clinical Research Institute (J.-P.T., A.T., I.G.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle Upon Tyne; and Centre for Public Health (J.P.M.K.), Queen's University Belfast, UK. .
White SR; From the Department of Psychiatry (E.M., S.R.W., A.S., J.T.O.) and MRC Biostatistics Unit (S.R.W.), University of Cambridge, UK; Forefront Parkinson's Disease Research Clinic (E.M., G.M.H., S.J.G.L.) and Brain and Mind Centre (E.M., G.M.H., S.J.G.L.), Faculty of Medicine and Health, University of Sydney, Australia; Newcastle Translational and Clinical Research Institute (J.-P.T., A.T., I.G.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle Upon Tyne; and Centre for Public Health (J.P.M.K.), Queen's University Belfast, UK.
Taylor JP; From the Department of Psychiatry (E.M., S.R.W., A.S., J.T.O.) and MRC Biostatistics Unit (S.R.W.), University of Cambridge, UK; Forefront Parkinson's Disease Research Clinic (E.M., G.M.H., S.J.G.L.) and Brain and Mind Centre (E.M., G.M.H., S.J.G.L.), Faculty of Medicine and Health, University of Sydney, Australia; Newcastle Translational and Clinical Research Institute (J.-P.T., A.T., I.G.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle Upon Tyne; and Centre for Public Health (J.P.M.K.), Queen's University Belfast, UK.
Thomas A; From the Department of Psychiatry (E.M., S.R.W., A.S., J.T.O.) and MRC Biostatistics Unit (S.R.W.), University of Cambridge, UK; Forefront Parkinson's Disease Research Clinic (E.M., G.M.H., S.J.G.L.) and Brain and Mind Centre (E.M., G.M.H., S.J.G.L.), Faculty of Medicine and Health, University of Sydney, Australia; Newcastle Translational and Clinical Research Institute (J.-P.T., A.T., I.G.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle Upon Tyne; and Centre for Public Health (J.P.M.K.), Queen's University Belfast, UK.
McKeith IG; From the Department of Psychiatry (E.M., S.R.W., A.S., J.T.O.) and MRC Biostatistics Unit (S.R.W.), University of Cambridge, UK; Forefront Parkinson's Disease Research Clinic (E.M., G.M.H., S.J.G.L.) and Brain and Mind Centre (E.M., G.M.H., S.J.G.L.), Faculty of Medicine and Health, University of Sydney, Australia; Newcastle Translational and Clinical Research Institute (J.-P.T., A.T., I.G.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle Upon Tyne; and Centre for Public Health (J.P.M.K.), Queen's University Belfast, UK.
Kane JPM; From the Department of Psychiatry (E.M., S.R.W., A.S., J.T.O.) and MRC Biostatistics Unit (S.R.W.), University of Cambridge, UK; Forefront Parkinson's Disease Research Clinic (E.M., G.M.H., S.J.G.L.) and Brain and Mind Centre (E.M., G.M.H., S.J.G.L.), Faculty of Medicine and Health, University of Sydney, Australia; Newcastle Translational and Clinical Research Institute (J.-P.T., A.T., I.G.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle Upon Tyne; and Centre for Public Health (J.P.M.K.), Queen's University Belfast, UK.
Surendranathan A; From the Department of Psychiatry (E.M., S.R.W., A.S., J.T.O.) and MRC Biostatistics Unit (S.R.W.), University of Cambridge, UK; Forefront Parkinson's Disease Research Clinic (E.M., G.M.H., S.J.G.L.) and Brain and Mind Centre (E.M., G.M.H., S.J.G.L.), Faculty of Medicine and Health, University of Sydney, Australia; Newcastle Translational and Clinical Research Institute (J.-P.T., A.T., I.G.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle Upon Tyne; and Centre for Public Health (J.P.M.K.), Queen's University Belfast, UK.
Halliday GM; From the Department of Psychiatry (E.M., S.R.W., A.S., J.T.O.) and MRC Biostatistics Unit (S.R.W.), University of Cambridge, UK; Forefront Parkinson's Disease Research Clinic (E.M., G.M.H., S.J.G.L.) and Brain and Mind Centre (E.M., G.M.H., S.J.G.L.), Faculty of Medicine and Health, University of Sydney, Australia; Newcastle Translational and Clinical Research Institute (J.-P.T., A.T., I.G.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle Upon Tyne; and Centre for Public Health (J.P.M.K.), Queen's University Belfast, UK.
Lewis SJG; From the Department of Psychiatry (E.M., S.R.W., A.S., J.T.O.) and MRC Biostatistics Unit (S.R.W.), University of Cambridge, UK; Forefront Parkinson's Disease Research Clinic (E.M., G.M.H., S.J.G.L.) and Brain and Mind Centre (E.M., G.M.H., S.J.G.L.), Faculty of Medicine and Health, University of Sydney, Australia; Newcastle Translational and Clinical Research Institute (J.-P.T., A.T., I.G.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle Upon Tyne; and Centre for Public Health (J.P.M.K.), Queen's University Belfast, UK.
O'Brien JT; From the Department of Psychiatry (E.M., S.R.W., A.S., J.T.O.) and MRC Biostatistics Unit (S.R.W.), University of Cambridge, UK; Forefront Parkinson's Disease Research Clinic (E.M., G.M.H., S.J.G.L.) and Brain and Mind Centre (E.M., G.M.H., S.J.G.L.), Faculty of Medicine and Health, University of Sydney, Australia; Newcastle Translational and Clinical Research Institute (J.-P.T., A.T., I.G.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle Upon Tyne; and Centre for Public Health (J.P.M.K.), Queen's University Belfast, UK.
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Źródło :
Neurology [Neurology] 2021 Sep 07; Vol. 97 (10), pp. e1031-e1040. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Progression*
Lewy Body Disease*/physiopathology
Aged ; Aged, 80 and over ; Cognitive Dysfunction/physiopathology ; Female ; Humans ; Longitudinal Studies ; Male ; Parkinson Disease/physiopathology
Czasopismo naukowe
Tytuł :
COVID-19-accelerated disease progression in two patients with amyotrophic lateral sclerosis.
Autorzy :
Li X; Duke ALS Clinic, Department of Neurology, Duke University School of Medicine, Durham, North Carolina, USA.
Bedlack R; Duke ALS Clinic, Department of Neurology, Duke University School of Medicine, Durham, North Carolina, USA.
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Źródło :
Muscle & nerve [Muscle Nerve] 2021 Sep; Vol. 64 (3), pp. E13-E15. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Disease Progression*
Amyotrophic Lateral Sclerosis/*complications
Amyotrophic Lateral Sclerosis/*diagnosis
COVID-19/*complications
COVID-19/*diagnosis
Aged ; Fatal Outcome ; Humans ; Male
Raport
Tytuł :
Sustained decrease in pediatric asthma emergency visits during the first year of the COVID-19 pandemic.
Autorzy :
Arsenault S; From the Division of Allergy and Immunology, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, and.
Hoofman J; From the Division of Allergy and Immunology, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, and.
Poowuttikul P; Division of Allergy and Immunology, Department of Pediatrics, Central Michigan University School of Medicine, Mount Pleasant, Michigan.
Secord E; From the Division of Allergy and Immunology, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, and.
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Źródło :
Allergy and asthma proceedings [Allergy Asthma Proc] 2021 Sep 01; Vol. 42 (5), pp. 400-402.
Typ publikacji :
Journal Article
MeSH Terms :
Asthma*/etiology
Asthma*/physiopathology
Asthma*/therapy
Disease Progression*
COVID-19/*prevention & control
Emergency Service, Hospital/*trends
Facilities and Services Utilization/*trends
Acute Disease ; Adolescent ; Child ; Child, Preschool ; Environmental Exposure/prevention & control ; Environmental Exposure/statistics & numerical data ; Female ; Humans ; Male ; Michigan ; Physical Distancing ; Schools ; Urban Health
Czasopismo naukowe
Tytuł :
Impact of COVID-19 national lockdown on asthma exacerbations: interrupted time-series analysis of English primary care data.
Autorzy :
Shah SA; Asthma UK Centre for Applied Research, Centre for Medical Informatics, Usher Institute, The University of Edinburgh, Edinburgh, UK .
Quint JK; National Heart & Lung Institute, Imperial College London, London, UK.
Nwaru BI; Asthma UK Centre for Applied Research, Centre for Medical Informatics, Usher Institute, The University of Edinburgh, Edinburgh, UK.; Krefting Research Centre, The University of Edinburgh, Gothenburg, Sweden.
Sheikh A; Asthma UK Centre for Applied Research, Centre for Medical Informatics, Usher Institute, The University of Edinburgh, Edinburgh, UK.
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Źródło :
Thorax [Thorax] 2021 Sep; Vol. 76 (9), pp. 860-866. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Progression*
Symptom Flare Up*
Asthma/*epidemiology
COVID-19/*prevention & control
Primary Health Care/*statistics & numerical data
Administration, Oral ; Adolescent ; Adrenal Cortex Hormones/therapeutic use ; Adult ; Asthma/drug therapy ; Emergency Service, Hospital/statistics & numerical data ; England/epidemiology ; Female ; Humans ; Interrupted Time Series Analysis ; Male ; Middle Aged ; Patient Admission/statistics & numerical data ; SARS-CoV-2 ; Young Adult
Czasopismo naukowe
Tytuł :
Overexpression of dopamine receptor D2 promotes colorectal cancer progression by activating the β-catenin/ZEB1 axis.
Autorzy :
Lee H; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Seoul, Korea.
Shim S; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Seoul, Korea.
Kong JS; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Seoul, Korea.; Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Science, Seoul, Korea.
Kim MJ; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Seoul, Korea.
Park S; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Seoul, Korea.; Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Science, Seoul, Korea.
Lee SS; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Seoul, Korea.; Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Science, Seoul, Korea.
Kim A; Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Seoul, Korea.
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Źródło :
Cancer science [Cancer Sci] 2021 Sep; Vol. 112 (9), pp. 3732-3743. Date of Electronic Publication: 2021 Jul 04.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Progression*
Colorectal Neoplasms/*metabolism
Colorectal Neoplasms/*mortality
Receptors, Dopamine D2/*metabolism
Zinc Finger E-box-Binding Homeobox 1/*metabolism
beta Catenin/*metabolism
Aged ; Animals ; Cell Movement/genetics ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Dopamine Antagonists/pharmacology ; Female ; HCT116 Cells ; HT29 Cells ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Middle Aged ; Pimozide/pharmacology ; RNA Interference ; Receptors, Dopamine D2/genetics ; Signal Transduction ; Survival Rate ; Transfection ; Tumor Burden/drug effects ; Tumor Burden/genetics ; Up-Regulation ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Evidence of lung perfusion defects and ongoing inflammation in an adolescent with post-acute sequelae of SARS-CoV-2 infection.
Autorzy :
Buonsenso D; Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy; Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy; Global Health Research Institute, Istituto di Igiene, Università Cattolica del Sacro Cuore, Rome, Italy; Dipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Sezione di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy. Electronic address: .
Di Giuda D; Nuclear Medicine Unit, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy; Istituto di Medicina Nucleare, Università Cattolica del Sacro Cuore, Rome, Italy.
Sigfrid L; International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) Global Support Centre, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Pizzuto DA; Nuclear Medicine Unit, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Di Sante G; Dipartimento di Medicina e Chirurgia Traslazionale, Sezione di Patologia Generale, Università Cattolica del Sacro Cuore, Rome, Italy.
De Rose C; Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy; Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy.
Lazzareschi I; Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy; Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy.
Sali M; Dipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Sezione di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Baldi F; Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy.
Chieffo DPR; Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy; Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy; Clinical Psychology Unit, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy.
Munblit D; Department of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; Inflammation, Repair and Development Section, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK.
Valentini P; Dipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy; Global Health Research Institute, Istituto di Igiene, Università Cattolica del Sacro Cuore, Rome, Italy.
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Źródło :
The Lancet. Child & adolescent health [Lancet Child Adolesc Health] 2021 Sep; Vol. 5 (9), pp. 677-680. Date of Electronic Publication: 2021 Jul 31.
Typ publikacji :
Case Reports; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Progression*
Inflammation*
Perfusion*
COVID-19/*complications
Lung/*physiopathology
SARS-CoV-2/*physiology
Adolescent ; COVID-19/immunology ; Female ; Humans ; Longitudinal Studies
SCR Disease Name :
post-acute COVID-19 syndrome
Raport
Tytuł :
Sex differences in the Buffalo Concussion Treadmill Test in adolescents with acute sport-related concussion.
Autorzy :
Chizuk HM; Department of Rehabilitation Sciences, School of Public Health and Health Professions, State University of New York at Buffalo, United States of America; UBMD Orthopedics and Sports Medicine, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, United States of America. Electronic address: .
Willer BS; Department of Rehabilitation Sciences, School of Public Health and Health Professions, State University of New York at Buffalo, United States of America; Department of Psychiatry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, United States of America.
Horn EC; UBMD Orthopedics and Sports Medicine, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, United States of America.
Haider MN; UBMD Orthopedics and Sports Medicine, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, United States of America.
Leddy JJ; Department of Rehabilitation Sciences, School of Public Health and Health Professions, State University of New York at Buffalo, United States of America; UBMD Orthopedics and Sports Medicine, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, United States of America.
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Źródło :
Journal of science and medicine in sport [J Sci Med Sport] 2021 Sep; Vol. 24 (9), pp. 876-880. Date of Electronic Publication: 2021 Apr 30.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Progression*
Sex Factors*
Athletic Injuries/*physiopathology
Brain Concussion/*physiopathology
Exercise Tolerance/*physiology
Heart Rate/*physiology
Adolescent ; Exercise Test/methods ; Female ; Humans ; Male ; New York ; Prospective Studies ; Rest/physiology ; Time Factors ; Visual Analog Scale
Czasopismo naukowe
Tytuł :
Interrelationship between the 5-lipoxygenase pathway and microbial dysbiosis in the progression of Alzheimer's disease.
Autorzy :
Mathis SP; Department of Microbiology and Immunology, James Graham Brown Cancer Center and Center for Microbiomics, Inflammation and Pathogenicity, Louisville, KY 40202, United States of America; University of Louisville Health Sciences Center, Louisville, KY 40202, United States of America.
Bodduluri SR; Department of Microbiology and Immunology, James Graham Brown Cancer Center and Center for Microbiomics, Inflammation and Pathogenicity, Louisville, KY 40202, United States of America; University of Louisville Health Sciences Center, Louisville, KY 40202, United States of America.
Haribabu B; Department of Microbiology and Immunology, James Graham Brown Cancer Center and Center for Microbiomics, Inflammation and Pathogenicity, Louisville, KY 40202, United States of America; University of Louisville Health Sciences Center, Louisville, KY 40202, United States of America. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2021 Sep; Vol. 1866 (9), pp. 158982. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Disease Progression*
Alzheimer Disease/*enzymology
Alzheimer Disease/*microbiology
Arachidonate 5-Lipoxygenase/*metabolism
Dysbiosis/*complications
Alzheimer Disease/complications ; Animals ; Brain/metabolism ; Disease Models, Animal ; Gastrointestinal Microbiome ; Mice
Czasopismo naukowe
Tytuł :
Discovery of Parkinson's disease states and disease progression modelling: a longitudinal data study using machine learning.
Autorzy :
Severson KA; Center for Computational Health, IBM Research, Cambridge, MA, USA. Electronic address: .
Chahine LM; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
Smolensky LA; Michael J Fox Foundation, New York, NY, USA.
Dhuliawala M; Center for Computational Health, IBM Research, Cambridge, MA, USA.
Frasier M; Michael J Fox Foundation, New York, NY, USA.
Ng K; Center for Computational Health, IBM Research, Cambridge, MA, USA.
Ghosh S; Center for Computational Health, IBM Research, Cambridge, MA, USA.
Hu J; Center for Computational Health, IBM Research, Yorktown Heights, NY, USA.
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Źródło :
The Lancet. Digital health [Lancet Digit Health] 2021 Sep; Vol. 3 (9), pp. e555-e564. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Progression*
Machine Learning*
Models, Statistical*
Parkinson Disease/*diagnosis
Parkinson Disease/*pathology
Aged ; Biological Variation, Individual ; Biological Variation, Population ; Dopamine Agents/therapeutic use ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Parkinson Disease/drug therapy
Czasopismo naukowe
Tytuł :
The nonsmokers' and smokers' pathways in lung adenocarcinoma: Histological progression and molecular bases.
Autorzy :
Okudela K; Department of Pathology, Graduate School of Medicine, Yokohama City University, Yokohama, China.
Matsumura M; Department of Pathology, Graduate School of Medicine, Yokohama City University, Yokohama, China.
Arai H; Devision of General Thoracic Surgery, Kanagawa Cardiovascular and Respiratory Center Hospital, Yokohama, China.
Woo T; Devision of Thoracic Surgery, Yokohama City University Medical Center Hospital, Yokohama, China.
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Źródło :
Cancer science [Cancer Sci] 2021 Sep; Vol. 112 (9), pp. 3411-3418. Date of Electronic Publication: 2021 Jul 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Disease Progression*
Non-Smokers*
Smokers*
Smoking*
Adenocarcinoma of Lung/*genetics
Adenocarcinoma of Lung/*metabolism
Lung Neoplasms/*genetics
Lung Neoplasms/*metabolism
Adenocarcinoma of Lung/pathology ; Adult ; Aged ; Aged, 80 and over ; ErbB Receptors/genetics ; Female ; Humans ; Lung/pathology ; Lung Neoplasms/pathology ; Male ; Middle Aged ; Mutation ; Proto-Oncogene Proteins p21(ras)/genetics ; Tumor Suppressor Protein p53/genetics
Czasopismo naukowe
Tytuł :
Progressive Neurochemical Abnormalities in Cognitive and Motor Subgroups of Amyotrophic Lateral Sclerosis: A Prospective Multicenter Study.
Autorzy :
Ta D; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada. .
Ishaque A; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Srivastava O; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Hanstock C; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Seres P; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Eurich DT; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Luk C; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Briemberg H; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Frayne R; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Genge AL; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Graham SJ; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Korngut L; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Zinman L; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada.
Kalra S; From the Neuroscience and Mental Health Institute (D.T., A.I., O.S., S.K.), Department of Biomedical Engineering (C.H., P.S.), School of Public Health (D.T.E.), and Division of Neurology (C.L., S.K.), University of Alberta, Edmonton; Division of Neurology (H.B.), University of British Columbia, Vancouver; Seaman Family MR Centre (R.F.) and Hotchkiss Brain Institute (R.F., L.K.), University of Calgary, Alberta; Montreal Neurological Institute (A.L.G.), McGill University, Quebec; and Sunnybrook Health Sciences Centre (S.J.G., L.Z.), University of Toronto, Ontario, Canada. .
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Źródło :
Neurology [Neurology] 2021 Aug 24; Vol. 97 (8), pp. e803-e813. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji :
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Progression*
Magnetic Resonance Spectroscopy*/methods
Amyotrophic Lateral Sclerosis/*metabolism
Aspartic Acid/*analogs & derivatives
Cognitive Dysfunction/*metabolism
Motor Cortex/*metabolism
Prefrontal Cortex/*metabolism
Adult ; Aged ; Amyotrophic Lateral Sclerosis/complications ; Amyotrophic Lateral Sclerosis/diagnostic imaging ; Amyotrophic Lateral Sclerosis/pathology ; Aspartic Acid/metabolism ; Cognitive Dysfunction/diagnostic imaging ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/pathology ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Motor Cortex/diagnostic imaging ; Motor Cortex/pathology ; Prefrontal Cortex/diagnostic imaging ; Prefrontal Cortex/pathology ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Secondary Progressive Multiple Sclerosis: New Insights.
Autorzy :
Cree BAC; From the UCSF Weill Institute for Neurosciences, Department of Neurology (B.A.C.C.), University of California San Francisco; NeuroRx Research (D.L.A.), Montreal; Brain Imaging Centre (D.L.A.), Montreal Neurological Institute, McGill University, Canada; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation (J.C.), UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London; National Institute for Health Research (J.C.), University College London Hospitals, Biomedical Research Centre, UK; Brigham Multiple Sclerosis Center (T.C.), Brigham and Women's Hospital, Boston, MA; Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute (R.J.F.), Cleveland Clinic, OH; Oxford PharmaGenesis (A.P.R.), UK; Novartis Pharma AG (N.M.), Basel, Switzerland; and Center for Brain Research (H.L.), Medical University of Vienna, Austria. .
Arnold DL; From the UCSF Weill Institute for Neurosciences, Department of Neurology (B.A.C.C.), University of California San Francisco; NeuroRx Research (D.L.A.), Montreal; Brain Imaging Centre (D.L.A.), Montreal Neurological Institute, McGill University, Canada; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation (J.C.), UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London; National Institute for Health Research (J.C.), University College London Hospitals, Biomedical Research Centre, UK; Brigham Multiple Sclerosis Center (T.C.), Brigham and Women's Hospital, Boston, MA; Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute (R.J.F.), Cleveland Clinic, OH; Oxford PharmaGenesis (A.P.R.), UK; Novartis Pharma AG (N.M.), Basel, Switzerland; and Center for Brain Research (H.L.), Medical University of Vienna, Austria.
Chataway J; From the UCSF Weill Institute for Neurosciences, Department of Neurology (B.A.C.C.), University of California San Francisco; NeuroRx Research (D.L.A.), Montreal; Brain Imaging Centre (D.L.A.), Montreal Neurological Institute, McGill University, Canada; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation (J.C.), UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London; National Institute for Health Research (J.C.), University College London Hospitals, Biomedical Research Centre, UK; Brigham Multiple Sclerosis Center (T.C.), Brigham and Women's Hospital, Boston, MA; Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute (R.J.F.), Cleveland Clinic, OH; Oxford PharmaGenesis (A.P.R.), UK; Novartis Pharma AG (N.M.), Basel, Switzerland; and Center for Brain Research (H.L.), Medical University of Vienna, Austria.
Chitnis T; From the UCSF Weill Institute for Neurosciences, Department of Neurology (B.A.C.C.), University of California San Francisco; NeuroRx Research (D.L.A.), Montreal; Brain Imaging Centre (D.L.A.), Montreal Neurological Institute, McGill University, Canada; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation (J.C.), UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London; National Institute for Health Research (J.C.), University College London Hospitals, Biomedical Research Centre, UK; Brigham Multiple Sclerosis Center (T.C.), Brigham and Women's Hospital, Boston, MA; Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute (R.J.F.), Cleveland Clinic, OH; Oxford PharmaGenesis (A.P.R.), UK; Novartis Pharma AG (N.M.), Basel, Switzerland; and Center for Brain Research (H.L.), Medical University of Vienna, Austria.
Fox RJ; From the UCSF Weill Institute for Neurosciences, Department of Neurology (B.A.C.C.), University of California San Francisco; NeuroRx Research (D.L.A.), Montreal; Brain Imaging Centre (D.L.A.), Montreal Neurological Institute, McGill University, Canada; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation (J.C.), UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London; National Institute for Health Research (J.C.), University College London Hospitals, Biomedical Research Centre, UK; Brigham Multiple Sclerosis Center (T.C.), Brigham and Women's Hospital, Boston, MA; Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute (R.J.F.), Cleveland Clinic, OH; Oxford PharmaGenesis (A.P.R.), UK; Novartis Pharma AG (N.M.), Basel, Switzerland; and Center for Brain Research (H.L.), Medical University of Vienna, Austria.
Pozo Ramajo A; From the UCSF Weill Institute for Neurosciences, Department of Neurology (B.A.C.C.), University of California San Francisco; NeuroRx Research (D.L.A.), Montreal; Brain Imaging Centre (D.L.A.), Montreal Neurological Institute, McGill University, Canada; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation (J.C.), UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London; National Institute for Health Research (J.C.), University College London Hospitals, Biomedical Research Centre, UK; Brigham Multiple Sclerosis Center (T.C.), Brigham and Women's Hospital, Boston, MA; Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute (R.J.F.), Cleveland Clinic, OH; Oxford PharmaGenesis (A.P.R.), UK; Novartis Pharma AG (N.M.), Basel, Switzerland; and Center for Brain Research (H.L.), Medical University of Vienna, Austria.
Murphy N; From the UCSF Weill Institute for Neurosciences, Department of Neurology (B.A.C.C.), University of California San Francisco; NeuroRx Research (D.L.A.), Montreal; Brain Imaging Centre (D.L.A.), Montreal Neurological Institute, McGill University, Canada; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation (J.C.), UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London; National Institute for Health Research (J.C.), University College London Hospitals, Biomedical Research Centre, UK; Brigham Multiple Sclerosis Center (T.C.), Brigham and Women's Hospital, Boston, MA; Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute (R.J.F.), Cleveland Clinic, OH; Oxford PharmaGenesis (A.P.R.), UK; Novartis Pharma AG (N.M.), Basel, Switzerland; and Center for Brain Research (H.L.), Medical University of Vienna, Austria.
Lassmann H; From the UCSF Weill Institute for Neurosciences, Department of Neurology (B.A.C.C.), University of California San Francisco; NeuroRx Research (D.L.A.), Montreal; Brain Imaging Centre (D.L.A.), Montreal Neurological Institute, McGill University, Canada; Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation (J.C.), UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London; National Institute for Health Research (J.C.), University College London Hospitals, Biomedical Research Centre, UK; Brigham Multiple Sclerosis Center (T.C.), Brigham and Women's Hospital, Boston, MA; Mellen Center for Multiple Sclerosis Treatment and Research, Neurological Institute (R.J.F.), Cleveland Clinic, OH; Oxford PharmaGenesis (A.P.R.), UK; Novartis Pharma AG (N.M.), Basel, Switzerland; and Center for Brain Research (H.L.), Medical University of Vienna, Austria.
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Źródło :
Neurology [Neurology] 2021 Aug 24; Vol. 97 (8), pp. 378-388. Date of Electronic Publication: 2021 Jun 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Biomarkers*
Disease Progression*
Immunologic Factors/*pharmacology
Multiple Sclerosis, Chronic Progressive/*diagnosis
Humans ; Multiple Sclerosis, Chronic Progressive/immunology ; Multiple Sclerosis, Chronic Progressive/pathology ; Multiple Sclerosis, Chronic Progressive/physiopathology
Czasopismo naukowe
Tytuł :
Longitudinal Network Changes and Conversion to Cognitive Impairment in Multiple Sclerosis.
Autorzy :
Huiskamp M; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK. .
Eijlers AJC; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.
Broeders TAA; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.
Pasteuning J; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.
Dekker I; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.
Uitdehaag BMJ; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.
Barkhof F; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.
Wink AM; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.
Geurts JJG; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.
Hulst HE; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.
Schoonheim MM; From the Department of Anatomy and Neurosciences (M.H., A.J.C.E., T.A.A.B., J.P., J.J.G.G., H.E.H., M.M.S.), Department of Neurology (I.D., B.M.J.U.), and Department of Radiology and Nuclear Medicine (I.D., F.B., A.-M.W.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, the Netherlands; and UCL Institutes of Neurology and Healthcare Engineering (F.B.), London, UK.
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Źródło :
Neurology [Neurology] 2021 Aug 24; Vol. 97 (8), pp. e794-e802. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain*/diagnostic imaging
Brain*/pathology
Brain*/physiopathology
Disease Progression*
Cognitive Dysfunction/*diagnosis
Cognitive Dysfunction/*physiopathology
Default Mode Network/*physiopathology
Multiple Sclerosis/*diagnosis
Nerve Net/*physiopathology
Adult ; Cognitive Dysfunction/diagnostic imaging ; Cognitive Dysfunction/etiology ; Default Mode Network/diagnostic imaging ; Female ; Humans ; Longitudinal Studies ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Multiple Sclerosis/complications ; Nerve Net/diagnostic imaging ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
MiR-616 promotes the progression of pancreatic carcinoma by targeting OXR1.
Autorzy :
Zhou Y; Department of General Surgery, Ezhou Central Hospital, Ezhou, China.
Meng P; Department of Oncology, Ezhou Central Hospital, Ezhou, China.
Tang B; Department of General Surgery, Ezhou Central Hospital, Ezhou, China.
Ke Z; Department of General Surgery, Ezhou Central Hospital, Ezhou, China.
Liu L; Department of General Surgery, Ezhou Central Hospital, Ezhou, China.
Chen Y; Department of General Surgery, Ezhou Central Hospital, Ezhou, China.
Zhu F; Department of General Surgery, Ezhou Central Hospital, Ezhou, China - .
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Źródło :
Minerva medica [Minerva Med] 2021 Aug; Vol. 112 (4), pp. 528-529. Date of Electronic Publication: 2019 Sep 06.
Typ publikacji :
Letter
MeSH Terms :
Disease Progression*
MicroRNAs/*metabolism
Mitochondrial Proteins/*metabolism
Pancreatic Neoplasms/*pathology
Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Down-Regulation ; Humans ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Neoplasm Invasiveness ; Pancreatic Neoplasms/metabolism ; Up-Regulation
SCR Disease Name :
Pancreatic Carcinoma
Opinia redakcyjna
Tytuł :
Upregulated level of lncRNA HOXA-AS2 in peripheral blood of systemic lupus erythematosus patients aggravates disease progression via ERK pathway.
Autorzy :
Wu W; Interventional Operating Room, The First Hospital of China Medical University, Shenyang, China.
Jing Y; Department of Vascular Surgery, The First Hospital of China Medical University, Shenyang, China.
Xu Q; Interventional Operating Room, The First Hospital of China Medical University, Shenyang, China.
Hao J; Interventional Operating Room, The First Hospital of China Medical University, Shenyang, China.
Yu X; Department of Pain, The First Hospital of China Medical University, Shenyang, China - .
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Źródło :
Minerva medica [Minerva Med] 2021 Aug; Vol. 112 (4), pp. 536-537. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Letter
MeSH Terms :
Disease Progression*
MAP Kinase Signaling System*
Lupus Erythematosus, Systemic/*blood
RNA, Long Noncoding/*blood
Down-Regulation ; Female ; Humans ; Lupus Erythematosus, Systemic/genetics ; Male ; Mitogen-Activated Protein Kinase 1/blood ; Mitogen-Activated Protein Kinase 3/blood ; Sex Factors ; Up-Regulation
Opinia redakcyjna
Tytuł :
Unique structural features of the adenylate kinase hCINAP/AK6 and its multifaceted functions in carcinogenesis and tumor progression.
Autorzy :
Xu R; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.; Department of Biochemistry and Molecular Biology, School of Life Sciences, Peking University, Beijing, China.
Yang Y; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.; Department of Biochemistry and Molecular Biology, School of Life Sciences, Peking University, Beijing, China.
Zheng X; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China.; Department of Biochemistry and Molecular Biology, School of Life Sciences, Peking University, Beijing, China.
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Źródło :
FEBS letters [FEBS Lett] 2021 Aug; Vol. 595 (16), pp. 2071-2084. Date of Electronic Publication: 2021 Jul 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Carcinogenesis*
Disease Progression*
DNA-Binding Proteins/*chemistry
DNA-Binding Proteins/*metabolism
Neoplasms/*enzymology
Neoplasms/*pathology
Humans
Czasopismo naukowe
Tytuł :
Adverse Health Effects in People with and without Preexisting Respiratory Conditions during Bushfire Smoke Exposure in the 2019/2020 Australian Summer.
Autorzy :
MacIntyre CR; The Kirby Institute at University of New South Wales Sydney, New South Wales, Australia.; Arizona State University College of Public Affairs and Community Solutions Phoenix, Arizona.
Nguyen PY; The Kirby Institute at University of New South Wales Sydney, New South Wales, Australia.; University of New South Wales School of Population Health Sydney, New South Wales, Australia.
Trent M; The Kirby Institute at University of New South Wales Sydney, New South Wales, Australia.
Seale H; University of New South Wales School of Population Health Sydney, New South Wales, Australia.
Chughtai AA; University of New South Wales School of Population Health Sydney, New South Wales, Australia.
Shah S; Western Sydney Local Health District Prevention Education and Research Unit Westmead, New South Wales, Australia.; The University of Sydney Faculty of Medicine and Health Sydney, New South Wales, Australia.
Marks GB; Woolcock Institute of Medical Research Glebe, New South Wales, Australia.; University of New South Wales South Western Sydney Clinical School Liverpool, New South Wales, Australia.
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Źródło :
American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2021 Aug 01; Vol. 204 (3), pp. 368-371.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Progression*
Wildfires*
Emergency Service, Hospital/*statistics & numerical data
Hospitalization/*statistics & numerical data
Inhalation Exposure/*adverse effects
Lung Diseases/*physiopathology
Smoke/*adverse effects
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents/therapeutic use ; Asthma/drug therapy ; Asthma/physiopathology ; Australia ; Bronchiectasis/drug therapy ; Bronchiectasis/physiopathology ; Bronchitis, Chronic/drug therapy ; Bronchitis, Chronic/physiopathology ; Bronchodilator Agents/therapeutic use ; Chronic Disease ; Cross-Sectional Studies ; Female ; Glucocorticoids/therapeutic use ; Humans ; Lung Diseases/drug therapy ; Male ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/physiopathology ; Pulmonary Emphysema/drug therapy ; Pulmonary Emphysema/physiopathology ; Young Adult
Raport
Tytuł :
Geriatric antibody response to COVID-19.
Autorzy :
Moore J; School of Medicine, West Virginia University, Morgantown, West Virginia, USA.
Groves T; School of Medicine, West Virginia University, Morgantown, West Virginia, USA.
Pilkerton CS; Department of Family Medicine, West Virginia University, Morgantown, West Virginia, USA.
Ashcraft AM; Department of Family Medicine, West Virginia University, Morgantown, West Virginia, USA.
Shrader CD; Department of Family Medicine, West Virginia University, Morgantown, West Virginia, USA.
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Źródło :
Journal of the American Geriatrics Society [J Am Geriatr Soc] 2021 Aug; Vol. 69 (8), pp. 2096-2098. Date of Electronic Publication: 2021 May 03.
Typ publikacji :
Letter; Research Support, N.I.H., Extramural
MeSH Terms :
Disease Progression*
Antibody Formation/*immunology
COVID-19/*epidemiology
Geriatrics/*statistics & numerical data
Aged, 80 and over ; Comorbidity ; Humans ; Immunoglobulin G ; Long-Term Care ; Time Factors ; West Virginia/epidemiology
Raport

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