Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ
Zmień bibliotekę

Wyszukujesz frazę ""Drug Therapy, Combination"" wg kryterium: Temat


Tytuł :
DrugComb update: a more comprehensive drug sensitivity data repository and analysis portal.
Autorzy :
Zheng S; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki FI-00290, Finland.
Aldahdooh J; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki FI-00290, Finland.
Shadbahr T; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki FI-00290, Finland.
Wang Y; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki FI-00290, Finland.
Aldahdooh D; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki FI-00290, Finland.
Bao J; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki FI-00290, Finland.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki FI-00290, Finland.
Wang W; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki FI-00290, Finland.
Tang J; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki FI-00290, Finland.
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jul 02; Vol. 49 (W1), pp. W174-W184.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Algorithms*
Databases, Factual*
Drug Evaluation, Preclinical*
Drug Therapy, Combination*
Internet*
COVID-19/drug therapy ; Data Visualization ; Datasets as Topic ; Drug Synergism ; Hemorrhagic Fever, Ebola/drug therapy ; Humans ; Machine Learning ; Malaria/drug therapy ; Neoplasms/drug therapy
Czasopismo naukowe
Tytuł :
QT effects of bedaquiline, delamanid, or both in patients with rifampicin-resistant tuberculosis: a phase 2, open-label, randomised, controlled trial.
Autorzy :
Dooley KE; Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: .
Rosenkranz SL; Frontier Science Foundation, Brookline, MA, USA.
Conradie F; University of Witwatersrand, Johannesburg, South Africa.
Moran L; Social & Scientific Systems, Silver Spring, MD, USA.
Hafner R; Division of AIDS, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
von Groote-Bidlingmaier F; TASK Applied Science, Cape Town, South Africa.
Lama JR; Asociación Civil Impacta Salud y Educacion, Lima, Peru.
Shenje J; South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine, Cape Town, South Africa; Department of Medicine, University of Cape Town, Cape Town, South Africa.
De Los Rios J; Asociación Civil Impacta Salud y Educacion, Lima, Peru.
Comins K; TASK Applied Science, Cape Town, South Africa.
Morganroth J; ERT, Philadelphia, PA, USA.
Diacon AH; TASK Applied Science, Cape Town, South Africa; Stellenbosch University, Cape Town, South Africa.
Cramer YS; Frontier Science Foundation, Brookline, MA, USA.
Donahue K; Frontier Science and Technology Research Foundation, Amherst, NY, USA.
Maartens G; Division of Clinical Pharmacology, Department of Medicine, Cape Town, South Africa.
Pokaż więcej
Corporate Authors :
AIDS Clinical Trials Group (ACTG) A5343 DELIBERATE Study Team
Źródło :
The Lancet. Infectious diseases [Lancet Infect Dis] 2021 Jul; Vol. 21 (7), pp. 975-983. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Therapy, Combination*
Antitubercular Agents/*therapeutic use
Diarylquinolines/*therapeutic use
Nitroimidazoles/*therapeutic use
Oxazoles/*therapeutic use
Tuberculosis, Multidrug-Resistant/*drug therapy
Adult ; Electrocardiography/drug effects ; Female ; Humans ; Male ; Peru ; Rifampin ; South Africa ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Efficacy and Safety of Dual Antiplatelet Therapy in Patients Undergoing Coronary Stent Implantation: A Systematic Review and Network Meta-Analysis.
Autorzy :
Xu Y; Department of Cardiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, Zhejiang 310009, China.
Shen Y; Department of Cardiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, Zhejiang 310009, China.
Chen D; Department of Cardiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, Zhejiang 310009, China.
Zhao P; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, 138 Xianlin Avenue, Nanjing 210023, China.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, China.
Jiang J; Department of Cardiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, Zhejiang 310009, China.
Pokaż więcej
Źródło :
Journal of interventional cardiology [J Interv Cardiol] 2021 May 05; Vol. 2021, pp. 9934535. Date of Electronic Publication: 2021 May 05 (Print Publication: 2021).
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Drug Therapy, Combination*/adverse effects
Drug Therapy, Combination*/methods
Drug-Eluting Stents*
Percutaneous Coronary Intervention*/adverse effects
Percutaneous Coronary Intervention*/instrumentation
Percutaneous Coronary Intervention*/methods
Coronary Restenosis/*prevention & control
Platelet Aggregation Inhibitors/*pharmacology
Hemorrhage/chemically induced ; Hemorrhage/prevention & control ; Humans ; Network Meta-Analysis ; Risk Adjustment/methods
Czasopismo naukowe
Tytuł :
The role of combination therapy in the treatment of severe infections caused by carbapenem resistant gram-negatives: a systematic review of clinical studies.
Autorzy :
Savoldi A; Division of Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, P.Le L.A. Scuro 10, 37134, Verona, Italy. .
Carrara E; Division of Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, P.Le L.A. Scuro 10, 37134, Verona, Italy.
Piddock LJV; Global Antibiotic Research & Development Partnership (GARDP), 15 Chemin Louis-Dunant, Geneva, Switzerland.
Franceschi F; Global Antibiotic Research & Development Partnership (GARDP), 15 Chemin Louis-Dunant, Geneva, Switzerland.
Ellis S; Global Antibiotic Research & Development Partnership (GARDP), 15 Chemin Louis-Dunant, Geneva, Switzerland.
Chiamenti M; Division of Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, P.Le L.A. Scuro 10, 37134, Verona, Italy.
Bragantini D; Division of Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, P.Le L.A. Scuro 10, 37134, Verona, Italy.
Righi E; Division of Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, P.Le L.A. Scuro 10, 37134, Verona, Italy.
Tacconelli E; Division of Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, P.Le L.A. Scuro 10, 37134, Verona, Italy.; Division of Infectious Diseases, Department of Internal Medicine I, German Center for Infection Research, University of Tübingen, Otfried Müller Straße 12, 72074, Tübingen, Germany.; German Centre for Infection Research (DZIF), Clinical Research Unit for Healthcare Associated Infections, Tübingen, Germany.
Pokaż więcej
Źródło :
BMC infectious diseases [BMC Infect Dis] 2021 Jun 09; Vol. 21 (1), pp. 545. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Systematic Review
MeSH Terms :
Drug Resistance, Bacterial*
Drug Therapy, Combination*
Gram-Negative Bacteria*
Anti-Bacterial Agents/*therapeutic use
Gram-Negative Bacterial Infections/*drug therapy
Acinetobacter baumannii ; Carbapenems ; Clinical Studies as Topic ; Enterobacteriaceae ; Humans ; Pseudomonas aeruginosa
Tytuł :
Safety and efficacy of upadacitinib in combination with topical corticosteroids in adolescents and adults with moderate-to-severe atopic dermatitis (AD Up): results from a randomised, double-blind, placebo-controlled, phase 3 trial.
Autorzy :
Reich K; Translational Research in Inflammatory Skin Diseases, Institute for Health Services Research in Dermatology and Nursing, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: .
Teixeira HD; AbbVie, North Chicago, IL, USA.
de Bruin-Weller M; Department of Dermatology and Allergology, National Expertise Center of Atopic Dermatitis, University Medical Center Utrecht, Utrecht, Netherlands.
Bieber T; Department of Dermatology and Allergy, University Hospital of Bonn, Bonn, Germany.
Soong W; Alabama Allergy and Asthma Center and Clinical Research Center of Alabama, Birmingham, AL, USA.
Kabashima K; Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Werfel T; Department of Dermatology and Allergy, Division of Immunodermatology and Allergy Research, Hannover Medical School, Hannover, Germany.
Zeng J; AbbVie, North Chicago, IL, USA.
Huang X; AbbVie, North Chicago, IL, USA.
Hu X; AbbVie, North Chicago, IL, USA.
Hendrickson BA; AbbVie, North Chicago, IL, USA.
Ladizinski B; AbbVie, North Chicago, IL, USA.
Chu AD; AbbVie, North Chicago, IL, USA.
Silverberg JI; Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
Pokaż więcej
Źródło :
Lancet (London, England) [Lancet] 2021 Jun 05; Vol. 397 (10290), pp. 2169-2181. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Therapy, Combination*
Severity of Illness Index*
Adrenal Cortex Hormones/*therapeutic use
Dermatitis, Atopic/*drug therapy
Heterocyclic Compounds, 3-Ring/*therapeutic use
Janus Kinase Inhibitors/*therapeutic use
Adult ; Dose-Response Relationship, Drug ; Double-Blind Method ; Female ; Heterocyclic Compounds, 3-Ring/administration & dosage ; Humans ; Internationality ; Janus Kinase 1 ; Janus Kinase Inhibitors/administration & dosage ; Male
Czasopismo naukowe
Tytuł :
Network controllability-based algorithm to target personalized driver genes for discovering combinatorial drugs of individual patients.
Autorzy :
Guo WF; Key Laboratory of Information Fusion Technology of Ministry of Education, School of Automation, Northwestern Polytechnical University, Xian 710072, China.; School of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, China.
Zhang SW; Key Laboratory of Information Fusion Technology of Ministry of Education, School of Automation, Northwestern Polytechnical University, Xian 710072, China.
Feng YH; Key Laboratory of Information Fusion Technology of Ministry of Education, School of Automation, Northwestern Polytechnical University, Xian 710072, China.
Liang J; School of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, China.
Zeng T; CAS Key Laboratory of Computational Biology, Bio-Med Big Data Center, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.; Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy Science, Shanghai 200031, China.
Chen L; Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy Science, Shanghai 200031, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming 650223, China.; Key Laboratory of Systems Biology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Hangzhou 310024, China.
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Apr 19; Vol. 49 (7), pp. e37.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Algorithms*
Drug Therapy, Combination*
Breast Neoplasms/*drug therapy
Breast Neoplasms/*genetics
Lung Neoplasms/*drug therapy
Lung Neoplasms/*genetics
Precision Medicine/*methods
Breast Neoplasms/classification ; COVID-19/drug therapy ; COVID-19/genetics ; Datasets as Topic ; Drug Repositioning ; Drug Synergism ; Drug-Related Side Effects and Adverse Reactions ; Gene Expression Regulation, Neoplastic/genetics ; Genes, Neoplasm/genetics ; Humans ; Risk Assessment ; Workflow
Czasopismo naukowe
Tytuł :
Multicenter point prevalence evaluation of the utilization and safety of drug therapies for COVID-19 at the onset of the pandemic timeline in the United States.
Autorzy :
Rhodes NJ; Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL, USA.; Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, USA.; Pharmacometrics Center of Excellence, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, USA.
Dairem A; Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL, USA.
Moore WJ; Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL, USA.
Shah A; Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL, USA.; Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, USA.
Postelnick MJ; Department of Pharmacy, Northwestern Memorial Hospital, Chicago, IL, USA.
Badowski ME; Department of Pharmacy Practice, Section of Infectious Diseases Pharmacotherapy, University of Illinois at Chicago, College of Pharmacy, Chicago, IL, USA.
Michienzi SM; Department of Pharmacy Practice, Section of Infectious Diseases Pharmacotherapy, University of Illinois at Chicago, College of Pharmacy, Chicago, IL, USA.
Borkowski JL; Department of Pharmacy, Northwestern Medicine Delnor Hospital, Geneva, IL, USA.
Polisetty RS; Department of Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, USA.; Department of Pharmacy, Northwestern Medicine Central DuPage Hospital, Winfield, IL, USA.
Fong K; Department of Pharmacy, University of Utah Health.
Spivak ES; Department of Medicine, University of Utah School of Medicine.
Beardsley JR; Department of Pharmacy, Wake Forest Baptist Health, Winston-Salem, NC, USA.; Wake Forest School of Medicine, Winston-Salem, NC, USA.
Hale CM; Department of Pharmacy, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA.
Pallotta AM; Department of Pharmacy, Cleveland Clinic Hospital, Cleveland, OH, USA.
Srinivas P; Department of Pharmacy, Cleveland Clinic Hospital, Cleveland, OH, USA.
Schulz LT; Department of Pharmacy, University of Wisconsin Health, Madison WI, USA.
Pokaż więcej
Źródło :
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists [Am J Health Syst Pharm] 2021 Mar 18; Vol. 78 (7), pp. 568-577.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
SARS-CoV-2*
COVID-19/*drug therapy
Drug Therapy, Combination/*statistics & numerical data
Drug-Related Side Effects and Adverse Reactions/*epidemiology
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antiviral Agents/adverse effects ; Antiviral Agents/therapeutic use ; Child ; Child, Preschool ; Drug Therapy, Combination/adverse effects ; Female ; Humans ; Hydroxychloroquine/adverse effects ; Hydroxychloroquine/therapeutic use ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Pandemics ; Prevalence ; Retrospective Studies ; United States/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł :
Difficult to Treat and Severe Asthma: Management Strategies.
Autorzy :
Narasimhan K; Howard University College of Medicine, Washington, DC, USA.
Pokaż więcej
Źródło :
American family physician [Am Fam Physician] 2021 Mar 01; Vol. 103 (5), pp. 286-290.
Typ publikacji :
Journal Article
MeSH Terms :
Administration, Inhalation*
Drug Therapy, Combination*
Practice Guidelines as Topic*
Anti-Asthmatic Agents/*administration & dosage
Anti-Asthmatic Agents/*therapeutic use
Asthma/*diagnosis
Asthma/*drug therapy
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Asthma/epidemiology ; Curriculum ; Education, Medical, Continuing ; Female ; Health Personnel/education ; Humans ; Male ; Middle Aged ; United States/epidemiology ; Young Adult
Czasopismo naukowe
Tytuł :
Xuanbai Chengqi decoction plus Western Medicine in treatment of severe pneumonia with symptom pattern of phlegm-heat obstructing lung: a Meta-analysis.
Autorzy :
Yin X; Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing 210001, China.
Cheng N; Xinglong Community Health Centre, Nanjing 210019, China.
Zhu J; Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Pokaż więcej
Źródło :
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan [J Tradit Chin Med] 2021 Feb; Vol. 41 (1), pp. 17-25.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Drug Therapy, Combination*
Drugs, Chinese Herbal/*administration & dosage
Pneumonia/*drug therapy
Hot Temperature ; Humans ; Lung/drug effects ; Lung/metabolism ; Mucus/chemistry ; Mucus/drug effects ; Mucus/metabolism ; Pneumonia/physiopathology ; Randomized Controlled Trials as Topic ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Triple Artemisinin-Based Combination Therapies for Malaria - A New Paradigm?
Autorzy :
van der Pluijm RW; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Amaratunga C; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Dhorda M; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK; WorldWide Antimalarial Resistance Network - Asia-Pacific Regional Centre, Bangkok, Thailand.
Dondorp AM; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: .
Pokaż więcej
Źródło :
Trends in parasitology [Trends Parasitol] 2021 Jan; Vol. 37 (1), pp. 15-24. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Drug Therapy, Combination*
Artemisinins/*therapeutic use
Malaria, Falciparum/*drug therapy
Antimalarials/pharmacology ; Antimalarials/therapeutic use ; Artemisinins/pharmacology ; Asia, Southeastern ; Drug Resistance ; Humans ; Plasmodium falciparum/drug effects
Czasopismo naukowe
Tytuł :
Randomized Controlled Comparison of Optimal Medical Therapy with Percutaneous Recanalization of Chronic Total Occlusion (COMET-CTO).
Autorzy :
Juricic SA; Clinic for Cardiology, Clinical Center of Serbia.
Tesic MB; Clinic for Cardiology, Clinical Center of Serbia.; School of Medicine, University of Belgrade.
Galassi AR; University of Palermo.; Royal Brompton & Harefield NHS Foundation Trust.
Petrovic ON; Clinic for Cardiology, Clinical Center of Serbia.
Dobric MR; Clinic for Cardiology, Clinical Center of Serbia.; School of Medicine, University of Belgrade.
Orlic DN; Clinic for Cardiology, Clinical Center of Serbia.; School of Medicine, University of Belgrade.
Vukcevic VD; Clinic for Cardiology, Clinical Center of Serbia.; School of Medicine, University of Belgrade.
Stankovic GR; Clinic for Cardiology, Clinical Center of Serbia.; School of Medicine, University of Belgrade.; Serbian Academy of Sciences and Arts.
Aleksandric SB; Clinic for Cardiology, Clinical Center of Serbia.; School of Medicine, University of Belgrade.
Tomasevic MV; Clinic for Cardiology, Clinical Center of Serbia.; Department of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac.
Nedeljkovic MA; Clinic for Cardiology, Clinical Center of Serbia.; School of Medicine, University of Belgrade.
Beleslin BD; Clinic for Cardiology, Clinical Center of Serbia.; School of Medicine, University of Belgrade.
Jelic DD; Clinic for Cardiology, Clinical Center of Serbia.
Ostojic MC; School of Medicine, University of Belgrade.; Serbian Academy of Sciences and Arts.
Stojkovic SM; Clinic for Cardiology, Clinical Center of Serbia.; School of Medicine, University of Belgrade.
Pokaż więcej
Źródło :
International heart journal [Int Heart J] 2021; Vol. 62 (1), pp. 16-22.
Typ publikacji :
Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms :
Drug Therapy, Combination*
Percutaneous Coronary Intervention*
Coronary Occlusion/*drug therapy
Coronary Occlusion/*surgery
Aged ; Chronic Disease ; Female ; Humans ; Male ; Middle Aged ; Platelet Aggregation Inhibitors/therapeutic use ; Quality of Life
Czasopismo naukowe
Tytuł :
14-Day High-Dose Amoxicillin- and Metronidazole-Containing Triple Therapy With or Without Bismuth as First-Line Helicobacter pylori Treatment.
Autorzy :
Luo L; Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Road, Shanghai, 200001, China.
Ji Y; Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Road, Shanghai, 200001, China.
Yu L; Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Road, Shanghai, 200001, China.
Huang Y; Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Road, Shanghai, 200001, China.
Liang X; Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Road, Shanghai, 200001, China.
Graham DY; Department of Medicine, Michael E. DeBakey Veterans Affairs Medical Center, Baylor College of Medicine, Houston, TX, USA.
Lu H; Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 145 Middle Shandong Road, Shanghai, 200001, China. .; Clinical Research Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
Pokaż więcej
Źródło :
Digestive diseases and sciences [Dig Dis Sci] 2020 Dec; Vol. 65 (12), pp. 3639-3646. Date of Electronic Publication: 2020 Feb 04.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Therapy, Combination*/methods
Drug Therapy, Combination*/statistics & numerical data
Helicobacter Infections*/diagnosis
Helicobacter Infections*/drug therapy
Helicobacter pylori*/drug effects
Helicobacter pylori*/isolation & purification
Amoxicillin/*administration & dosage
Bismuth/*administration & dosage
Metronidazole/*administration & dosage
Proton Pump Inhibitors/*administration & dosage
Anti-Bacterial Agents/administration & dosage ; Breath Tests/methods ; Drug Monitoring/methods ; Drug Resistance ; Female ; Gastrointestinal Agents/administration & dosage ; Humans ; Male ; Microbial Sensitivity Tests/methods ; Middle Aged ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Association Between Benzodiazepine Use With or Without Opioid Use and All-Cause Mortality in the United States, 1999-2015.
Autorzy :
Xu KY; Health and Behavior Research Center, Department of Psychiatry, Washington University School of Medicine in St Louis, St Louis, Missouri.
Hartz SM; Health and Behavior Research Center, Department of Psychiatry, Washington University School of Medicine in St Louis, St Louis, Missouri.
Borodovsky JT; Health and Behavior Research Center, Department of Psychiatry, Washington University School of Medicine in St Louis, St Louis, Missouri.
Bierut LJ; Health and Behavior Research Center, Department of Psychiatry, Washington University School of Medicine in St Louis, St Louis, Missouri.; Alvin J. Siteman Cancer Center, Barnes Jewish Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.
Grucza RA; Health and Behavior Research Center, Department of Psychiatry, Washington University School of Medicine in St Louis, St Louis, Missouri.; Center for Health Outcomes Research, St Louis University, St Louis, Missouri.
Pokaż więcej
Źródło :
JAMA network open [JAMA Netw Open] 2020 Dec 01; Vol. 3 (12), pp. e2028557. Date of Electronic Publication: 2020 Dec 01.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Chronic Disease*/epidemiology
Chronic Disease*/therapy
Drug Therapy, Combination*/mortality
Drug Therapy, Combination*/statistics & numerical data
Mental Disorders*/drug therapy
Mental Disorders*/epidemiology
Analgesics, Opioid/*therapeutic use
Benzodiazepines/*therapeutic use
Cohort Studies ; Comorbidity ; Female ; Humans ; Male ; Middle Aged ; Mortality ; Practice Patterns, Physicians'/trends ; Prescription Drugs/therapeutic use ; Proportional Hazards Models ; Retrospective Studies ; Risk Factors ; United States/epidemiology
Czasopismo naukowe
Tytuł :
Treating Epilepsy Patients with Investigational Anti-COVID-19 Drugs: Recommendations by the Israeli Chapter of the ILAE.
Autorzy :
Ekstein D; Department of Neurology, Ginges Center of Human Neurogenetics, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Noyman I; Pediatric Neurology Unit, Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Fahoum F; Epilepsy and EEG Unit, Neurology Division, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.; Sackler Faculty of Medicine ,Tel Aviv University, Tel Aviv, Israel.
Herskovitz M; Department of Neurology, Rambam Health Care Campus and Technion Faculty of Medicine, Haifa, Israel.
Linder I; Pediatric Epilepsy and Neurology Service, Barzilai Medical Center, Ashkelon, Israel.
Ben Zeev B; Pediatric Neurology Unit, Safra Pediatric Hospital, Sheba Medical Center, Tel Hashomer, Israel.
Eyal S; Institute for Drug Research, School of Pharmacy, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Pokaż więcej
Źródło :
The Israel Medical Association journal : IMAJ [Isr Med Assoc J] 2020 Nov; Vol. 11 (22), pp. 665-672.
Typ publikacji :
Journal Article; Practice Guideline
MeSH Terms :
Anticonvulsants*/classification
Anticonvulsants*/pharmacology
Antiviral Agents*/classification
Antiviral Agents*/pharmacology
Drug Interactions*
Drug Therapy, Combination*/adverse effects
Drug Therapy, Combination*/methods
Drug Therapy, Combination*/standards
Epilepsy*/diagnosis
Epilepsy*/drug therapy
Epilepsy*/epidemiology
Medication Therapy Management*/standards
Medication Therapy Management*/trends
COVID-19/*drug therapy
Comorbidity ; Drug Monitoring/methods ; Drug-Related Side Effects and Adverse Reactions/etiology ; Drug-Related Side Effects and Adverse Reactions/prevention & control ; Humans ; Israel/epidemiology ; Patient Selection ; Practice Guidelines as Topic ; Risk Adjustment/methods ; Risk Adjustment/trends ; SARS-CoV-2
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Combined Biologic and Immunomodulatory Therapy is Superior to Monotherapy for Decreasing the Risk of Inflammatory Bowel Disease-Related Complications.
Autorzy :
Targownik LE; Section of Gastroenterology, Division of Internal Medicine, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.; Mount Sinai Hospital Inflammatory Bowel Disease Centre, University of Toronto, Toronto, Ontario, Canada.
Benchimol EI; Children's Hospital of Eastern Ontario IBD Centre, Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Eastern Ontario, Ottawa, Canada.; Department of Pediatrics and School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada.; ICES, Toronto, Canada.
Bernstein CN; Section of Gastroenterology, Division of Internal Medicine, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Singh H; Section of Gastroenterology, Division of Internal Medicine, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.; Department of Community Health Sciences, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Tennakoon A; Section of Gastroenterology, Division of Internal Medicine, Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Zubieta AA; Arthritis Research Centre, University of British Columbia, Vancouver British Columbia, Canada.
Coward S; Department of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Jones J; Department of Internal Medicine, Dalhousie University, Halifax, NS, Canada.
Kaplan GG; Department of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Kuenzig ME; ICES, Toronto, Canada.
Murthy SK; The Ottawa Hospital IBD Centre, University of Ottawa and Ottawa Hospital Research Institute, Ottawa, Canada.
Nguyen GC; Mount Sinai Hospital Inflammatory Bowel Disease Centre, University of Toronto, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
Peña-Sánchez JN; Department of Community Health & Epidemiology, College of Medicine, University of Saskatchewan, Saskatoon, Canada.
Pokaż więcej
Źródło :
Journal of Crohn's & colitis [J Crohns Colitis] 2020 Oct 05; Vol. 14 (10), pp. 1354-1363.
Typ publikacji :
Journal Article
MeSH Terms :
Colitis, Ulcerative*/epidemiology
Colitis, Ulcerative*/therapy
Crohn Disease*/epidemiology
Crohn Disease*/therapy
Drug Therapy, Combination*/methods
Drug Therapy, Combination*/statistics & numerical data
Adalimumab/*therapeutic use
Biological Products/*therapeutic use
Immunologic Factors/*therapeutic use
Methotrexate/*therapeutic use
Adult ; Azathioprine/therapeutic use ; Canada/epidemiology ; Female ; Humans ; Infliximab/therapeutic use ; Male ; Outcome and Process Assessment, Health Care ; Patient Selection ; Practice Patterns, Physicians'/statistics & numerical data ; Treatment Failure ; Tumor Necrosis Factor Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Mifepristone Combination Therapy Compared With Misoprostol Monotherapy for the Management of Miscarriage: A Cost-Effectiveness Analysis.
Autorzy :
Berkley HH; Department of Obstetrics & Gynecology at Naval Medical Center San Diego, San Diego, California; and the Uniformed Services University, Bethesda, Maryland.
Greene HL
Wittenberger MD
Pokaż więcej
Źródło :
Obstetrics and gynecology [Obstet Gynecol] 2020 Oct; Vol. 136 (4), pp. 774-781.
Typ publikacji :
Journal Article
MeSH Terms :
Abortion, Incomplete*/chemically induced
Abortion, Incomplete*/economics
Abortion, Incomplete*/surgery
Abortion, Induced*/adverse effects
Abortion, Induced*/economics
Abortion, Induced*/methods
Drug Therapy, Combination*/economics
Drug Therapy, Combination*/methods
Mifepristone*/administration & dosage
Mifepristone*/economics
Misoprostol*/administration & dosage
Misoprostol*/economics
Abortifacient Agents/administration & dosage ; Abortifacient Agents/economics ; Cost-Benefit Analysis ; Dilatation and Curettage/economics ; Dilatation and Curettage/methods ; Female ; Humans ; Monte Carlo Method ; Practice Patterns, Physicians' ; Pregnancy
Czasopismo naukowe
Tytuł :
Joining forces: Leveraging novel combination therapies to combat infections with eukaryotic pathogens.
Autorzy :
Ham RE; Department of Biological Sciences, Clemson University, Clemson, South Carolina, Unites States of America.; Eukaryotic Pathogens Innovation Center (EPIC), Clemson University, Clemson, South Carolina, Unites States of America.
Temesvari LA; Department of Biological Sciences, Clemson University, Clemson, South Carolina, Unites States of America.; Eukaryotic Pathogens Innovation Center (EPIC), Clemson University, Clemson, South Carolina, Unites States of America.
Pokaż więcej
Źródło :
PLoS pathogens [PLoS Pathog] 2020 Dec 31; Vol. 16 (12), pp. e1009081. Date of Electronic Publication: 2020 Dec 31 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Drug Resistance/*physiology
Drug Therapy, Combination/*methods
Anti-Infective Agents/pharmacology ; Antifungal Agents/pharmacology ; Antineoplastic Agents/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Drug Resistance/drug effects ; Drug Resistance, Microbial/drug effects ; Drug Resistance, Microbial/physiology ; Drug Therapy, Combination/trends ; Eukaryota/pathogenicity ; Humans
Czasopismo naukowe
Tytuł :
Pharmacodynamic Comparison of Ticagrelor Monotherapy Versus Ticagrelor and Aspirin in Patients After Percutaneous Coronary Intervention: The TEMPLATE (Ticagrelor Monotherapy and Platelet Reactivity) Randomized Controlled Trial.
Autorzy :
Johnson TW; Bristol Heart InstituteUniversity Hospitals Bristol & Weston NHS Foundation Trust Bristol UK.
Baos S; Clinical Trials and Evaluation Unit Bristol Trials CentreBristol Medical SchoolUniversity of Bristol Bristol UK.
Collett L; Clinical Trials and Evaluation Unit Bristol Trials CentreBristol Medical SchoolUniversity of Bristol Bristol UK.
Hutchinson JL; School of Physiology, Pharmacology and Neuroscience University of Bristol Bristol UK.
Nkau M; Bristol Heart InstituteUniversity Hospitals Bristol & Weston NHS Foundation Trust Bristol UK.
Molina M; Bristol Heart InstituteUniversity Hospitals Bristol & Weston NHS Foundation Trust Bristol UK.
Aungraheeta R; School of Physiology, Pharmacology and Neuroscience University of Bristol Bristol UK.
Reilly-Stitt C; Bristol Heart InstituteUniversity Hospitals Bristol & Weston NHS Foundation Trust Bristol UK.
Bowles R; Bristol Heart InstituteUniversity Hospitals Bristol & Weston NHS Foundation Trust Bristol UK.
Reeves BC; Clinical Trials and Evaluation Unit Bristol Trials CentreBristol Medical SchoolUniversity of Bristol Bristol UK.
Rogers CA; Clinical Trials and Evaluation Unit Bristol Trials CentreBristol Medical SchoolUniversity of Bristol Bristol UK.
Mundell SJ; School of Physiology, Pharmacology and Neuroscience University of Bristol Bristol UK.
Baumbach A; William Harvey Research InstituteQueen Mary University of London London UK.
Mumford AD; Bristol Heart InstituteUniversity Hospitals Bristol & Weston NHS Foundation Trust Bristol UK.; School of Cellular and Molecular Medicine University of Bristol Bristol UK.
Pokaż więcej
Źródło :
Journal of the American Heart Association [J Am Heart Assoc] 2020 Dec 15; Vol. 9 (24), pp. e016495. Date of Electronic Publication: 2020 Dec 11.
Typ publikacji :
Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Acute Coronary Syndrome/*drug therapy
Drug Therapy, Combination/*adverse effects
Percutaneous Coronary Intervention/*adverse effects
Purinergic P2Y Receptor Antagonists/*pharmacology
Ticagrelor/*pharmacology
Acute Coronary Syndrome/blood ; Aged ; Arachidonic Acid/blood ; Aspirin/therapeutic use ; Drug Therapy, Combination/methods ; Dual Anti-Platelet Therapy/adverse effects ; Dual Anti-Platelet Therapy/methods ; Female ; Humans ; Male ; Middle Aged ; Peptide Fragments/drug effects ; Platelet Aggregation/drug effects ; Platelet Aggregation Inhibitors/therapeutic use ; Platelet Function Tests/methods ; Purinergic P2Y Receptor Antagonists/administration & dosage ; Purinergic P2Y Receptor Antagonists/therapeutic use ; Receptors, Thromboxane A2, Prostaglandin H2/agonists ; Ticagrelor/administration & dosage ; Ticagrelor/therapeutic use
Czasopismo naukowe
Tytuł :
Pharmacokinetics, tolerability, and clinical effectiveness of perampanel in Japanese patients with epilepsy.
Autorzy :
Yamamoto Y; Department of Clinical Research, NHO, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Shizuoka, 420-8688, Japan; Department of Clinical Pharmaceutics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Shizuoka, 422-8526, Japan. Electronic address: .
Shiratani Y; Department of Clinical Research, NHO, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Shizuoka, 420-8688, Japan.
Asai S; Department of Clinical Research, NHO, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Shizuoka, 420-8688, Japan.
Usui N; Department of Clinical Research, NHO, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Shizuoka, 420-8688, Japan.
Nishida T; Department of Clinical Research, NHO, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Shizuoka, 420-8688, Japan.
Imai K; Department of Clinical Research, NHO, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Shizuoka, 420-8688, Japan.
Kagawa Y; Department of Clinical Pharmaceutics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Shizuoka, 422-8526, Japan; Laboratory of Clinical Pharmacokinetics and Drug Safety, Shizuoka General Hospital, 4-27-1 Kita Ando, Shizuoka, 420-8527, Japan.
Takahashi Y; Department of Clinical Research, NHO, National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, 886 Urushiyama, Shizuoka, 420-8688, Japan; Department of Clinical Pharmaceutics, Graduate School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Shizuoka, 422-8526, Japan.
Pokaż więcej
Źródło :
Seizure [Seizure] 2020 Dec; Vol. 83, pp. 181-186. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Therapy, Combination*
Treatment Outcome*
Anticonvulsants/*therapeutic use
Epilepsy/*drug therapy
Adolescent ; Adult ; Anticonvulsants/administration & dosage ; Carbamazepine/therapeutic use ; Child ; Drug Interactions/physiology ; Drug Monitoring/methods ; Female ; Humans ; Japan ; Male ; Phenobarbital/therapeutic use ; Phenytoin/therapeutic use ; Seizures/drug therapy
Czasopismo naukowe
Tytuł :
On the coherence of model-based dose-finding designs for drug combination trials.
Autorzy :
Park Y; Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, WI, United States of America.
Liu S; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America.
Pokaż więcej
Źródło :
PloS one [PLoS One] 2020 Nov 30; Vol. 15 (11), pp. e0242561. Date of Electronic Publication: 2020 Nov 30 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Clinical Trials, Phase I as Topic*
Dose-Response Relationship, Drug*
Drug Therapy, Combination*
Algorithms ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Computer Simulation ; Drug Combinations ; Humans ; Maximum Tolerated Dose ; Neoplasms/drug therapy ; Research Design
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies