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Wyszukujesz frazę ""Hypoglycemic Agents"" wg kryterium: Temat


Tytuł :
Effect of oral semaglutide on the pharmacokinetics of thyroxine after dosing of levothyroxine and the influence of co-administered tablets on the pharmacokinetics of oral semaglutide in healthy subjects: an open-label, one-sequence crossover, single-center, multiple-dose, two-part trial.
Autorzy :
Hauge C; Clinical Pharmacology, Novo Nordisk A/S, Søborg, Denmark.
Breitschaft A; Klinikum Westend, PAREXEL International GmbH, Berlin, Germany.
Hartoft-Nielsen ML; Medical and Scientific, Novo Nordisk A/S, Søborg, Denmark.
Jensen S; Biostatistics, Novo Nordisk A/S, Søborg, Denmark.
Bækdal TA; Clinical Pharmacology, Novo Nordisk A/S, Søborg, Denmark.
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Źródło :
Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2021 Sep; Vol. 17 (9), pp. 1139-1148. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Controlled Clinical Trial; Journal Article
MeSH Terms :
Glucagon-Like Peptides/*administration & dosage
Hypoglycemic Agents/*administration & dosage
Thyroxine/*administration & dosage
Administration, Oral ; Adult ; Cross-Over Studies ; Drug Interactions ; Female ; Glucagon-Like Peptides/pharmacokinetics ; Glucagon-Like Peptides/pharmacology ; Humans ; Hypoglycemic Agents/pharmacokinetics ; Hypoglycemic Agents/pharmacology ; Male ; Tablets ; Thyroxine/pharmacokinetics ; Thyroxine/pharmacology
Czasopismo naukowe
Tytuł :
Probiotics-fermented blueberry juices as potential antidiabetic product: antioxidant, antimicrobial and antidiabetic potentials.
Autorzy :
Zhong H; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.; Ningbo Institute of Zhejiang University, Ningbo, China.
Abdullah; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.
Zhao M; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.; Ningbo Institute of Zhejiang University, Ningbo, China.
Tang J; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.; Ningbo Institute of Zhejiang University, Ningbo, China.
Deng L; College of Biological Science and Technology, Hubei Minzu University, Enshi, China.
Feng F; College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China.; Ningbo Institute of Zhejiang University, Ningbo, China.
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Źródło :
Journal of the science of food and agriculture [J Sci Food Agric] 2021 Aug 15; Vol. 101 (10), pp. 4420-4427. Date of Electronic Publication: 2021 Jan 27.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*analysis
Antioxidants/*analysis
Blueberry Plants/*chemistry
Fruit/*microbiology
Fruit and Vegetable Juices/*analysis
Hypoglycemic Agents/*analysis
Lactobacillus/*metabolism
Probiotics/*metabolism
Anti-Infective Agents/metabolism ; Anti-Infective Agents/pharmacology ; Antioxidants/metabolism ; Antioxidants/pharmacology ; Bacteria/drug effects ; Bacteria/growth & development ; Blueberry Plants/metabolism ; Blueberry Plants/microbiology ; Fermentation ; Fruit/metabolism ; Fruit and Vegetable Juices/microbiology ; Hep G2 Cells ; Humans ; Hypoglycemic Agents/metabolism ; Hypoglycemic Agents/pharmacology
Czasopismo naukowe
Tytuł :
Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes.
Autorzy :
Frías JP; From the National Research Institute, Los Angeles (J.P.F.); the Diabetes Research Centre, University of Leicester, and the National Institute of Health Research Leicester Biomedical Research Centre - both in Leicester, United Kingdom (M.J.D.); the Dallas Diabetes Research Center at Medical City, Dallas (J.R.); Centro de Investigaciones Metabólicas, Buenos Aires (F.C.P.M.); and Eli Lilly, Indianapolis (L.F.L., B.K.B., B.L., X.C., K.B.).
Davies MJ; From the National Research Institute, Los Angeles (J.P.F.); the Diabetes Research Centre, University of Leicester, and the National Institute of Health Research Leicester Biomedical Research Centre - both in Leicester, United Kingdom (M.J.D.); the Dallas Diabetes Research Center at Medical City, Dallas (J.R.); Centro de Investigaciones Metabólicas, Buenos Aires (F.C.P.M.); and Eli Lilly, Indianapolis (L.F.L., B.K.B., B.L., X.C., K.B.).
Rosenstock J; From the National Research Institute, Los Angeles (J.P.F.); the Diabetes Research Centre, University of Leicester, and the National Institute of Health Research Leicester Biomedical Research Centre - both in Leicester, United Kingdom (M.J.D.); the Dallas Diabetes Research Center at Medical City, Dallas (J.R.); Centro de Investigaciones Metabólicas, Buenos Aires (F.C.P.M.); and Eli Lilly, Indianapolis (L.F.L., B.K.B., B.L., X.C., K.B.).
Pérez Manghi FC; From the National Research Institute, Los Angeles (J.P.F.); the Diabetes Research Centre, University of Leicester, and the National Institute of Health Research Leicester Biomedical Research Centre - both in Leicester, United Kingdom (M.J.D.); the Dallas Diabetes Research Center at Medical City, Dallas (J.R.); Centro de Investigaciones Metabólicas, Buenos Aires (F.C.P.M.); and Eli Lilly, Indianapolis (L.F.L., B.K.B., B.L., X.C., K.B.).
Fernández Landó L; From the National Research Institute, Los Angeles (J.P.F.); the Diabetes Research Centre, University of Leicester, and the National Institute of Health Research Leicester Biomedical Research Centre - both in Leicester, United Kingdom (M.J.D.); the Dallas Diabetes Research Center at Medical City, Dallas (J.R.); Centro de Investigaciones Metabólicas, Buenos Aires (F.C.P.M.); and Eli Lilly, Indianapolis (L.F.L., B.K.B., B.L., X.C., K.B.).
Bergman BK; From the National Research Institute, Los Angeles (J.P.F.); the Diabetes Research Centre, University of Leicester, and the National Institute of Health Research Leicester Biomedical Research Centre - both in Leicester, United Kingdom (M.J.D.); the Dallas Diabetes Research Center at Medical City, Dallas (J.R.); Centro de Investigaciones Metabólicas, Buenos Aires (F.C.P.M.); and Eli Lilly, Indianapolis (L.F.L., B.K.B., B.L., X.C., K.B.).
Liu B; From the National Research Institute, Los Angeles (J.P.F.); the Diabetes Research Centre, University of Leicester, and the National Institute of Health Research Leicester Biomedical Research Centre - both in Leicester, United Kingdom (M.J.D.); the Dallas Diabetes Research Center at Medical City, Dallas (J.R.); Centro de Investigaciones Metabólicas, Buenos Aires (F.C.P.M.); and Eli Lilly, Indianapolis (L.F.L., B.K.B., B.L., X.C., K.B.).
Cui X; From the National Research Institute, Los Angeles (J.P.F.); the Diabetes Research Centre, University of Leicester, and the National Institute of Health Research Leicester Biomedical Research Centre - both in Leicester, United Kingdom (M.J.D.); the Dallas Diabetes Research Center at Medical City, Dallas (J.R.); Centro de Investigaciones Metabólicas, Buenos Aires (F.C.P.M.); and Eli Lilly, Indianapolis (L.F.L., B.K.B., B.L., X.C., K.B.).
Brown K; From the National Research Institute, Los Angeles (J.P.F.); the Diabetes Research Centre, University of Leicester, and the National Institute of Health Research Leicester Biomedical Research Centre - both in Leicester, United Kingdom (M.J.D.); the Dallas Diabetes Research Center at Medical City, Dallas (J.R.); Centro de Investigaciones Metabólicas, Buenos Aires (F.C.P.M.); and Eli Lilly, Indianapolis (L.F.L., B.K.B., B.L., X.C., K.B.).
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Corporate Authors :
SURPASS-2 Investigators
Źródło :
The New England journal of medicine [N Engl J Med] 2021 Aug 05; Vol. 385 (6), pp. 503-515. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Clinical Trial, Phase III; Comparative Study; Equivalence Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2/*drug therapy
Gastric Inhibitory Polypeptide/*administration & dosage
Glucagon-Like Peptides/*administration & dosage
Hypoglycemic Agents/*administration & dosage
Blood Glucose/analysis ; Diabetes Mellitus, Type 2/blood ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Drug Therapy, Combination ; Female ; Gastric Inhibitory Polypeptide/adverse effects ; Glucagon-Like Peptide-1 Receptor/agonists ; Glucagon-Like Peptides/adverse effects ; Glycated Hemoglobin A/analysis ; Humans ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/therapeutic use ; Incretins/therapeutic use ; Injections, Subcutaneous ; Male ; Metformin/therapeutic use ; Middle Aged ; Nausea/chemically induced ; Weight Loss/drug effects
Czasopismo naukowe
Tytuł :
Inhibitory effects of chondroitin sulfate on alpha-amylase activity: A potential hypoglycemic agent.
Autorzy :
Pang H; Department of Biophysics, School of Physics Science, The Key Laboratory of Bioactive Materials, Ministry of Education, Nankai University, Tianjin 300071, PR China.
Li J; Department of Biophysics, School of Physics Science, The Key Laboratory of Bioactive Materials, Ministry of Education, Nankai University, Tianjin 300071, PR China.
Miao Z; State Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Weijin Road 94, Tianjin 300071, PR China.
Li SJ; Department of Biophysics, School of Physics Science, The Key Laboratory of Bioactive Materials, Ministry of Education, Nankai University, Tianjin 300071, PR China; Qilu Institute of Technology, Shandong 250200, PR China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Aug 01; Vol. 184, pp. 289-296. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Chondroitin Sulfates/*administration & dosage
Diabetes Mellitus, Experimental/*drug therapy
Diabetes Mellitus, Type 2/*drug therapy
Hypoglycemic Agents/*administration & dosage
alpha-Amylases/*antagonists & inhibitors
Administration, Oral ; Animals ; Blood Glucose/drug effects ; Cattle ; Chondroitin Sulfates/chemistry ; Chondroitin Sulfates/pharmacology ; Diabetes Mellitus, Experimental/blood ; Diabetes Mellitus, Experimental/enzymology ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/chemically induced ; Diabetes Mellitus, Type 2/enzymology ; Hypoglycemic Agents/chemistry ; Hypoglycemic Agents/pharmacology ; Inhibitory Concentration 50 ; Male ; Mice ; Sharks ; Species Specificity ; Streptozocin ; Swine ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Effect of Intake of Food Hydrocolloids of Bacterial Origin on the Glycemic Response in Humans: Systematic Review and Narrative Synthesis.
Autorzy :
Alshammari NA; Department of Clinical Nutrition, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.; Translational Medical Sciences and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG7 2UH, UK.
Taylor MA; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre, National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham NG7 2UH, UK.
Stevenson R; Precision Imaging Beacon, University of Nottingham, Nottingham NG7 2UH, UK.
Gouseti O; Department of Food Science, University of Copenhagen, DK-1958 Copenhagen, Denmark.
Alyami J; Department of Diagnostic Radiology, Faculty of Applied Medical Science, King Abdulaziz University (KAU), Jeddah 21589, Saudi Arabia.
Muttakin S; Indonesian Agency for Agricultural Research and Development, Jakarta 12540, Indonesia.; School of Chemical Engineering, University of Birmingham, Birmingham B15 2TT, UK.
Bakalis S; Department of Food Science, University of Copenhagen, DK-1958 Copenhagen, Denmark.
Lovegrove A; Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK.
Aithal GP; Translational Medical Sciences and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG7 2UH, UK.
Marciani L; Translational Medical Sciences and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG7 2UH, UK.
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Źródło :
Nutrients [Nutrients] 2021 Jul 14; Vol. 13 (7). Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Systematic Review
MeSH Terms :
Glycemic Control*/adverse effects
Bacteria/*chemistry
Blood Glucose/*drug effects
Dextrans/*therapeutic use
Diabetes Mellitus, Type 2/*drug therapy
Glucans/*therapeutic use
Hypoglycemic Agents/*therapeutic use
Polysaccharides, Bacterial/*therapeutic use
Adolescent ; Adult ; Aged ; Biomarkers/blood ; Blood Glucose/metabolism ; Colloids ; Dextrans/adverse effects ; Dextrans/isolation & purification ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/diagnosis ; Female ; Glucans/adverse effects ; Glucans/isolation & purification ; Humans ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/isolation & purification ; Male ; Middle Aged ; Polysaccharides, Bacterial/adverse effects ; Polysaccharides, Bacterial/isolation & purification ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans.
Autorzy :
Kjeldsen TB; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Hubálek F; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Hjørringgaard CU; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Tagmose TM; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Nishimura E; Novo Nordisk A/S, Global Drug Discovery, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Stidsen CE; Novo Nordisk A/S, Global Drug Discovery, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Porsgaard T; Novo Nordisk A/S, Global Drug Discovery, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Fledelius C; Novo Nordisk A/S, Global Drug Discovery, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Refsgaard HHF; Novo Nordisk A/S, Global Drug Discovery, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Gram-Nielsen S; Novo Nordisk A/S, Global Drug Discovery, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Naver H; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Pridal L; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Hoeg-Jensen T; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Jeppesen CB; Novo Nordisk A/S, Global Drug Discovery, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Manfè V; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Ludvigsen S; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Lautrup-Larsen I; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
Madsen P; Novo Nordisk A/S, Global Research Technologies, Novo Nordisk Park, DK-2760 Maaloev, Denmark.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Jul 08; Vol. 64 (13), pp. 8942-8950. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2/*drug therapy
Hypoglycemic Agents/*pharmacology
Insulin/*pharmacology
Animals ; Dogs ; Drug Administration Schedule ; Humans ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/chemistry ; Injections, Intravenous ; Injections, Subcutaneous ; Insulin/administration & dosage ; Insulin/analogs & derivatives ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Icodec Advances the Prospect of Once-Weekly Insulin Injection.
Autorzy :
DiMarchi RD; Department of Chemistry, Indiana University, 800 East Kirkwood, Bloomington, Indiana 47405, United States.
Mayer JP; Department of MCD Biology, University of Colorado, 1945 Colorado Ave., Boulder, Colorado 80309, United States.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2021 Jul 08; Vol. 64 (13), pp. 8939-8941. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Introductory Journal Article
MeSH Terms :
Diabetes Mellitus, Type 2/*drug therapy
Hypoglycemic Agents/*therapeutic use
Insulin/*therapeutic use
Blood Glucose ; Diabetes Mellitus, Type 2/metabolism ; Drug Administration Schedule ; Humans ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/chemistry ; Infusions, Subcutaneous ; Insulin/administration & dosage ; Insulin/analogs & derivatives
Czasopismo naukowe
Tytuł :
Metformin-conjugated micellar system with intratumoral pH responsive de-shielding for co-delivery of doxorubicin and nucleic acid.
Autorzy :
Liu Y; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States.
Sun J; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States.
Huang Y; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States.
Chen Y; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States.
Li J; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States.
Liang L; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States.
Xu J; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States.
Wan Z; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States.
Zhang B; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States.
Li Z; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States.
Li S; Center for Pharmacogenetics, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, United States. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2021 Jul; Vol. 189, pp. 114453. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Micelles*
Doxorubicin/*administration & dosage
Drug Delivery Systems/*methods
Hypoglycemic Agents/*administration & dosage
Metformin/*administration & dosage
Nucleic Acids/*administration & dosage
Animals ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/physiology ; Dose-Response Relationship, Drug ; Doxorubicin/chemistry ; Doxorubicin/metabolism ; Female ; Hydrogen-Ion Concentration ; Hypoglycemic Agents/chemistry ; Hypoglycemic Agents/metabolism ; Metformin/chemistry ; Metformin/metabolism ; Mice ; Mice, Inbred BALB C ; Nucleic Acids/chemistry ; Nucleic Acids/metabolism
Czasopismo naukowe
Tytuł :
Hypoglycemia and Glycemic Control With Glyburide in Women With Gestational Diabetes and Genetic Variants of Cytochrome P450 2C9 and/or OATP1B3.
Autorzy :
Bouchghoul H; Department of Gynecology-Obstetrics, Assistance Publique-Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France.; CESP, Université Paris-Saclay, UVSQ, Inserm, Villejuif, France.
Bouyer J; CESP, Université Paris-Saclay, UVSQ, Inserm, Villejuif, France.
Senat MV; Department of Gynecology-Obstetrics, Assistance Publique-Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France.; CESP, Université Paris-Saclay, UVSQ, Inserm, Villejuif, France.
Mandelbrot L; Department of Gynecology and Obstetrics, Assistance Publique-Hôpitaux de Paris, Louis Mourier Hospital, Colombes, France.
Letourneau A; Department of Gynecology and Obstetrics, Assistance Publique-Hôpitaux de Paris, Antoine Béclère Hospital, Clamart, France.
Bourcigaux N; Department of Endocrinology, Assistance Publique-Hôpitaux de Paris, St Antoine Hospital Paris, Paris, France.
Becquemont L; CESP, Université Paris-Saclay, UVSQ, Inserm, Villejuif, France.; Service de Génétique moléculaire, Pharmacogénétique et Hormonologie, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Paris, France.
Verstuyft C; CESP, Université Paris-Saclay, UVSQ, Inserm, Villejuif, France.; Service de Génétique moléculaire, Pharmacogénétique et Hormonologie, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Paris, France.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Jul; Vol. 110 (1), pp. 141-148. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes, Gestational/*drug therapy
Glyburide/*administration & dosage
Hypoglycemia/*epidemiology
Hypoglycemic Agents/*administration & dosage
Adult ; Cytochrome P-450 CYP2C9/genetics ; Diabetes, Gestational/genetics ; Dose-Response Relationship, Drug ; Female ; Genetic Variation ; Genotype ; Glyburide/adverse effects ; Glyburide/pharmacokinetics ; Glycemic Control/methods ; Humans ; Hypoglycemia/genetics ; Hypoglycemic Agents/adverse effects ; Hypoglycemic Agents/pharmacokinetics ; Polymorphism, Genetic ; Pregnancy ; Solute Carrier Organic Anion Transporter Family Member 1B3/genetics
Czasopismo naukowe
Tytuł :
Efficacy and Safety of Enteral Recombinant Human Insulin for Reduction of Time-to-Full Enteral Feeding in Preterm Infants: A Randomized, Double-blind, Placebo-Controlled Trial.
Autorzy :
Shehadeh N; Department of Pediatrics A and the Pediatric Diabetes Unit, Rambam Health Care Campus, Haifa, Israel.
Simmonds A; Department of Neonatology/Pediatrics, Laniado Hospital, Netanya, Israel.
Zangen S; Department of Pediatrics, Barzilai Medical Center, Ashkelon, Israel.
Riskin A; Department of Neonatology, Bnai Zion Medical Center, Haifa, Israel.; Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Shamir R; Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center, Petah Tikva, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Źródło :
The Israel Medical Association journal : IMAJ [Isr Med Assoc J] 2021 Sep; Vol. 23 (9), pp. 563-568.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms :
Infant, Premature*
Enteral Nutrition/*statistics & numerical data
Hypoglycemic Agents/*administration & dosage
Insulin/*administration & dosage
Blood Glucose/drug effects ; Double-Blind Method ; Female ; Gestational Age ; Humans ; Hypoglycemic Agents/adverse effects ; Infant, Newborn ; Insulin/adverse effects ; Male ; Time Factors
Czasopismo naukowe
Tytuł :
Effect of four modification methods on adsorption capacities and in vitro hypoglycemic properties of millet bran dietary fibre.
Autorzy :
Zheng Y; College of Food Science, Shanxi Normal University, Linfen 041004, China. Electronic address: .
Wang X; College of Food Science, Shanxi Normal University, Linfen 041004, China.
Tian H; College of Food Science, Shanxi Normal University, Linfen 041004, China.
Li Y; College of Food Science, Shanxi Normal University, Linfen 041004, China.
Shi P; College of Food Science, Shanxi Normal University, Linfen 041004, China.
Guo W; College of Food Science, Shanxi Normal University, Linfen 041004, China.
Zhu Q; College of Food Science, Shanxi Normal University, Linfen 041004, China.
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Źródło :
Food research international (Ottawa, Ont.) [Food Res Int] 2021 Sep; Vol. 147, pp. 110565. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypoglycemic Agents*
Millets*
Adsorption ; Dietary Fiber ; Renal Dialysis
Czasopismo naukowe
Tytuł :
Biofunctionalities of unprocessed and processed flours of Australian lupin cultivars: Antidiabetic and organ protective potential studies.
Autorzy :
Mazumder K; Department of Pharmacy, Jashore University of Science and Technology, Jashore-7408, Jashore, Bangladesh; School of Biomedical Sciences and Graham Centre for Agricultural Innovation, Charles Sturt University, Boorooma St, Wagga Wagga, NSW, Australia. Electronic address: .
Rabiul Hossain M; Department of Pharmacy, Faculty of Basic Medical and Pharmaceutical Sciences, University of Science and Technology Chittagong, Foy's Lake, Chittagong 4202, Bangladesh.
Aktar A; Department of Pharmacy, Jashore University of Science and Technology, Jashore-7408, Jashore, Bangladesh.
Dash R; Department of Anatomy, Dongguk University College of Medicine, Gyeongju 38066, Republic of Korea.
Farahnaky A; School of Biomedical Sciences and Graham Centre for Agricultural Innovation, Charles Sturt University, Boorooma St, Wagga Wagga, NSW, Australia; Biosciences and Food Technology, School of Science, RMIT University, Bundoora West Campus, Plenty Road, Melbourne, Vic 3083, Australia.
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Źródło :
Food research international (Ottawa, Ont.) [Food Res Int] 2021 Sep; Vol. 147, pp. 110536. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Journal Article
MeSH Terms :
Flour*
Hypoglycemic Agents*/pharmacology
Animals ; Australia ; Plant Extracts/pharmacology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
GPR119 agonists for the treatment of type 2 diabetes: an updated patent review (2014-present).
Autorzy :
Li H; College of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang, China.
Fang Y; National Engineering Research Center for Manufacturing Technology of TCM Solid Preparation, Jiangxi University of Chinese Medicine, Nanchang, China.
Guo S; Medicinal Chemistry Department, Shanghai Jemincare Pharm Co., LTD, Shanghai, China.
Yang Z; College of Pharmacy, Jiangxi University of Chinese Medicine, Nanchang, China.
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Źródło :
Expert opinion on therapeutic patents [Expert Opin Ther Pat] 2021 Sep; Vol. 31 (9), pp. 795-808. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Diabetes Mellitus, Type 2/*drug therapy
Hypoglycemic Agents/*pharmacology
Receptors, G-Protein-Coupled/*agonists
Animals ; Diabetes Mellitus, Type 2/physiopathology ; Dipeptidyl-Peptidase IV Inhibitors/administration & dosage ; Dipeptidyl-Peptidase IV Inhibitors/pharmacology ; Drug Development ; Drug Synergism ; Glucose/metabolism ; Humans ; Hypoglycemic Agents/administration & dosage ; Incretins/metabolism ; Insulin/metabolism ; Patents as Topic ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Tytuł :
Selective extraction of galactomannan from fenugreek (Trigonella foenum-graecum L.) seed husk and its enzyme inhibitory potential associated with hyperglycaemia.
Autorzy :
Srinivasa UM; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; Department of Spices and Flavour Sciences, CSIR-CFTRI, Mysuru, India.
Naidu MM; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.; Department of Spices and Flavour Sciences, CSIR-CFTRI, Mysuru, India.
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Źródło :
Journal of the science of food and agriculture [J Sci Food Agric] 2021 Aug 30; Vol. 101 (11), pp. 4751-4759. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Journal Article
MeSH Terms :
Enzyme Inhibitors/*chemistry
Hypoglycemic Agents/*chemistry
Mannans/*chemistry
Plant Extracts/*chemistry
Trigonella/*chemistry
Enzyme Inhibitors/isolation & purification ; Glycoside Hydrolase Inhibitors/chemistry ; Glycoside Hydrolase Inhibitors/isolation & purification ; Humans ; Hyperglycemia/enzymology ; Hypoglycemic Agents/isolation & purification ; Mannans/isolation & purification ; Plant Extracts/isolation & purification ; alpha-Amylases/antagonists & inhibitors ; alpha-Amylases/chemistry ; alpha-Glucosidases/chemistry
Czasopismo naukowe
Tytuł :
A randomized controlled trial of transition from insulin pump to multiple daily injections using insulin degludec.
Autorzy :
Shah VN; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Akturk HK; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Joseph H; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Schneider N; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Snell-Bergeon JK; Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
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Źródło :
Diabetes, obesity & metabolism [Diabetes Obes Metab] 2021 Aug; Vol. 23 (8), pp. 1936-1941. Date of Electronic Publication: 2021 Jun 27.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 1*/drug therapy
Hypoglycemic Agents*/therapeutic use
Adult ; Blood Glucose ; Glycated Hemoglobin A/analysis ; Humans ; Insulin/therapeutic use ; Insulin Infusion Systems ; Insulin, Long-Acting/therapeutic use
Czasopismo naukowe
Tytuł :
Effective oral delivery of Exenatide-Zn complex through distal ileum-targeted double layers nanocarriers modified with deoxycholic acid and glycocholic acid in diabetes therapy.
Autorzy :
Han Y; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Liu W; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Chen L; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Xin X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Wang Q; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Zhang X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Jin M; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China.
Gao Z; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. Electronic address: .
Huang W; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. Electronic address: .
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Źródło :
Biomaterials [Biomaterials] 2021 Aug; Vol. 275, pp. 120944. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus*/drug therapy
Hypoglycemic Agents*
Exenatide/*administration & dosage
Administration, Oral ; Delayed-Action Preparations/administration & dosage ; Deoxycholic Acid ; Glycocholic Acid ; Humans ; Ileum ; Nanoparticles ; Zinc
Czasopismo naukowe
Tytuł :
Structural characterization, anticancer, hypoglycemia and immune activities of polysaccharides from Russula virescens.
Autorzy :
Li YM; School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China.
Zhong RF; School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China.
Chen J; School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China. Electronic address: .
Luo ZG; School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, China; Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health (111 Center), 381 Wushan Road, Guangzhou 510640, China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Aug 01; Vol. 184, pp. 380-392. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*chemistry
Antioxidants/*chemistry
Basidiomycota/*chemistry
Cytokines/*metabolism
Fungal Polysaccharides/*chemistry
Hypoglycemic Agents/*chemistry
A549 Cells ; Animals ; Antineoplastic Agents/pharmacology ; Antioxidants/pharmacology ; Carbohydrate Sequence ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Fungal Polysaccharides/pharmacology ; Glycoside Hydrolase Inhibitors/chemistry ; Glycoside Hydrolase Inhibitors/pharmacology ; Hep G2 Cells ; Humans ; Hypoglycemic Agents/pharmacology ; MCF-7 Cells ; Mice ; Molecular Weight ; RAW 264.7 Cells ; alpha-Amylases/antagonists & inhibitors
SCR Organism :
Russula virescens
Czasopismo naukowe
Tytuł :
Moisture and caking resistant Tremella fuciformis polysaccharides microcapsules with hypoglycemic activity.
Autorzy :
Niu B; Institute of Food Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Feng S; Department of Food Science and Technology, Zhejiang University of Technology, Zhejiang, Hangzhou 310014, China; Key Laboratory of Food Macromolecular Resources Processing Technology Research (Zhejiang University of Technology), China National Light Industry, Zhejiang, Hangzhou 310014, China.
Xuan S; Department of Food Science and Technology, Zhejiang University of Technology, Zhejiang, Hangzhou 310014, China.
Shao P; Department of Food Science and Technology, Zhejiang University of Technology, Zhejiang, Hangzhou 310014, China; Key Laboratory of Food Macromolecular Resources Processing Technology Research (Zhejiang University of Technology), China National Light Industry, Zhejiang, Hangzhou 310014, China. Electronic address: .
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Źródło :
Food research international (Ottawa, Ont.) [Food Res Int] 2021 Aug; Vol. 146, pp. 110420. Date of Electronic Publication: 2021 May 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypoglycemic Agents*
Phosphatidylinositol 3-Kinases*
Basidiomycota ; Capsules ; Polysaccharides
SCR Organism :
Tremella fuciformis
Czasopismo naukowe
Tytuł :
Lower glucose treatment threshold could be as safe as the traditional threshold in hypoglycaemic neonates.
Autorzy :
Gray K; Royal Hospital for Children, Glasgow, UK .
Dalrymple R; Royal Alexandra Hospital, Paisley, Renfrewshire, UK.
Brunton A; Neonatology, Royal Hospital for Children Glasgow, Glasgow, UK.
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Źródło :
Archives of disease in childhood. Education and practice edition [Arch Dis Child Educ Pract Ed] 2021 Aug; Vol. 106 (4), pp. 255-256. Date of Electronic Publication: 2020 Sep 08.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Hypoglycemia*/diagnosis
Hypoglycemic Agents*/adverse effects
Blood Glucose ; Humans ; Infant, Newborn
Czasopismo naukowe
Tytuł :
Sodium/Glucose Cotransporter 2 Inhibitors and the Risk of Diabetic Ketoacidosis: An Example of Complementary Evidence for Rare Adverse Events.
Autorzy :
Alkabbani W
Pelletier R
Gamble JM
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Źródło :
American journal of epidemiology [Am J Epidemiol] 2021 Aug 01; Vol. 190 (8), pp. 1572-1581.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Diabetes Mellitus, Type 2/*drug therapy
Diabetic Ketoacidosis/*chemically induced
Hypoglycemic Agents/*adverse effects
Sodium-Glucose Transporter 2 Inhibitors/*adverse effects
Humans ; Hypoglycemic Agents/therapeutic use ; Observational Studies as Topic ; Randomized Controlled Trials as Topic ; Reproducibility of Results ; Research Design ; Risk Factors ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use
Czasopismo naukowe

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