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Tytuł :
μSPE followed by HPLC-MS/MS for the determination of series D and E resolvins in biological matrices.
Autorzy :
Fanti F; University of Teramo, Faculty of Bioscience and Technology for Food, Agriculture and Environment, 64100, TE, Italy.
Oliva E; University of Teramo, Faculty of Bioscience and Technology for Food, Agriculture and Environment, 64100, TE, Italy.
Tortolani D; European Center for Brain Research, IRCCS Santa Lucia Foundation, 00164, Rome, Italy.
Di Meo C; University of Teramo, Faculty of Bioscience and Technology for Food, Agriculture and Environment, 64100, TE, Italy.
Fava M; University of Teramo, Faculty of Bioscience and Technology for Food, Agriculture and Environment, 64100, TE, Italy; European Center for Brain Research, IRCCS Santa Lucia Foundation, 00164, Rome, Italy.
Leuti A; Department of Medicine, Campus Bio-Medico University of Rome, 00128, Rome, Italy.
Rapino C; Faculty of Veterinary Medicine, University of Teramo, 64100, Teramo, Italy.
Sergi M; University of Teramo, Faculty of Bioscience and Technology for Food, Agriculture and Environment, 64100, TE, Italy. Electronic address: .
Maccarrone M; European Center for Brain Research, IRCCS Santa Lucia Foundation, 00164, Rome, Italy; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100, L'Aquila, Italy.
Compagnone D; University of Teramo, Faculty of Bioscience and Technology for Food, Agriculture and Environment, 64100, TE, Italy.
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Źródło :
Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2021 Sep 05; Vol. 203, pp. 114181. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Inflammation*
Tandem Mass Spectrometry*
Chromatography, High Pressure Liquid ; Humans ; Inflammation Mediators ; Solid Phase Extraction
Czasopismo naukowe
Tytuł :
Characterization of N -Octadecanoyl-5-hydroxytryptamide Anti-Inflammatory Effect.
Autorzy :
Giorno TBS; Laboratório de Farmacologia da Dor e da Inflamação, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Lima FA; Laboratório de Análise de Aromas, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Brand ALM; Laboratório de Análise de Aromas, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Oliveira CM; Laboratório de Análise de Aromas, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Rezende CM; Laboratório de Análise de Aromas, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
Fernandes PD; Laboratório de Farmacologia da Dor e da Inflamação, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, Brazil.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 18; Vol. 26 (12). Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Inflammation/*drug therapy
Serotonin/*pharmacology
Animals ; Carrageenan/pharmacology ; Cell Line ; Cell Movement/drug effects ; Cytokines/metabolism ; Disease Models, Animal ; Inflammation/chemically induced ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Interleukin-10/metabolism ; Leukocytes/drug effects ; Leukocytes/metabolism ; Macrophages/drug effects ; Macrophages/metabolism ; Male ; Mice ; Nitric Oxide/metabolism ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł :
The NR4A agonist, Cytosporone B, attenuates pro-inflammatory mediators in human colorectal cancer tissue ex vivo.
Autorzy :
Ismaiel M; School of Medicine, University College Dublin, Dublin, Ireland; Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland.
Murphy B; School of Medicine, University College Dublin, Dublin, Ireland; Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland.
Aldhafiri S; School of Veterinary Medicine, University College Dublin, Dublin, Ireland.
Giffney HE; School of Veterinary Medicine, University College Dublin, Dublin, Ireland.
Thornton K; School of Veterinary Medicine, University College Dublin, Dublin, Ireland.
Mukhopadhya A; School of Veterinary Medicine, University College Dublin, Dublin, Ireland.
Keogh CE; Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, CA, USA.
Fattah S; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
Mohan HM; Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland.
Cummins EP; School of Medicine, University College Dublin, Dublin, Ireland; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
Murphy EP; School of Medicine, University of Limerick, Limerick, Ireland.
Winter DC; School of Medicine, University College Dublin, Dublin, Ireland; Department of Surgery, St. Vincent's University Hospital, Dublin, Ireland. Electronic address: .
Crean D; School of Veterinary Medicine, University College Dublin, Dublin, Ireland; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 May 21; Vol. 554, pp. 179-185. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colorectal Neoplasms/*drug therapy
Inflammation Mediators/*metabolism
Nuclear Receptor Subfamily 4, Group A, Member 1/*agonists
Phenylacetates/*pharmacology
Adult ; Aged ; Aged, 80 and over ; Chemokines/metabolism ; Colorectal Neoplasms/immunology ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Cytokines/metabolism ; Female ; Humans ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation/pathology ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Ribes nigrum Leaf Extract Preferentially Inhibits IFN-γ-Mediated Inflammation in HaCaT Keratinocytes.
Autorzy :
Magnavacca A; Department of Pharmacological and Molecular Sciences, University of Milan, 20133 Milan, Italy.
Piazza S; Department of Pharmacological and Molecular Sciences, University of Milan, 20133 Milan, Italy.
Cammisa A; Specialist in Dermatology and Venereology, Corso di Porta Romana 131, 20122 Milan, Italy.
Fumagalli M; Department of Pharmacological and Molecular Sciences, University of Milan, 20133 Milan, Italy.
Martinelli G; Department of Pharmacological and Molecular Sciences, University of Milan, 20133 Milan, Italy.
Giavarini F; Department of Pharmacological and Molecular Sciences, University of Milan, 20133 Milan, Italy.
Sangiovanni E; Department of Pharmacological and Molecular Sciences, University of Milan, 20133 Milan, Italy.
Dell'Agli M; Department of Pharmacological and Molecular Sciences, University of Milan, 20133 Milan, Italy.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 May 20; Vol. 26 (10). Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article
MeSH Terms :
Inflammation/*chemically induced
Interferon-gamma/*pharmacology
Keratinocytes/*drug effects
Plant Extracts/*pharmacology
Plant Leaves/*chemistry
Ribes/*chemistry
Cell Line ; Cytokines/administration & dosage ; Cytokines/metabolism ; Humans ; Inflammation Mediators/administration & dosage ; Inflammation Mediators/metabolism ; Intercellular Adhesion Molecule-1/metabolism ; Kaempferols/pharmacology ; Keratinocytes/metabolism ; NF-kappa B/metabolism ; Quercetin/pharmacology
Czasopismo naukowe
Tytuł :
Trefoil Factor Family (TFF) Peptides and Their Links to Inflammation: A Re-evaluation and New Medical Perspectives.
Autorzy :
Hoffmann W; Institute of Molecular Biology and Medicinal Chemistry, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 06; Vol. 22 (9). Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Inflammation/*metabolism
Inflammation/*pathology
Trefoil Factors/*metabolism
Animals ; Colon/pathology ; Humans ; Inflammation Mediators/metabolism ; Models, Biological ; Neoplasms/metabolism ; Neoplasms/pathology ; Trefoil Factors/chemistry
Czasopismo naukowe
Tytuł :
Glutathionylation chemistry promotes interleukin-1 beta-mediated glycolytic reprogramming and pro-inflammatory signaling in lung epithelial cells.
Autorzy :
Aboushousha R; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
Elko E; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
Chia SB; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
Manuel AM; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
van de Wetering C; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
van der Velden J; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
MacPherson M; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
Erickson C; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
Reisz JA; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, CO, USA.
D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, CO, USA.
Wouters EFM; Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, the Netherlands.; Ludwig Boltzmann Institute for Lung Research, Vienna, Austria.
Reynaert NL; Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Toxicology and Metabolism, Maastricht University Medical Center, Maastricht, the Netherlands.
Lam YW; Department of Biology, University of Vermont College of Medicine, Burlington, VT, USA.
Anathy V; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
van der Vliet A; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
Seward DJ; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
Janssen-Heininger YMW; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, VT, USA.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 May; Vol. 35 (5), pp. e21525.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Cellular Reprogramming*
Glycolysis*
Glutaredoxins/*physiology
Glutathione/*metabolism
Inflammation/*immunology
Interleukin-1beta/*pharmacology
Lung/*immunology
Animals ; Cytokines/metabolism ; Epithelial Cells/cytology ; Epithelial Cells/drug effects ; Epithelial Cells/immunology ; Epithelial Cells/metabolism ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Lung/cytology ; Lung/drug effects ; Lung/metabolism ; Metabolome ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
Ozone inhalation induces exacerbation of eosinophilic airway inflammation and Th2-skew immune response in a rat model of AR.
Autorzy :
Sun N; Department of Otolaryngology, Huadong Hospital, Fudan University, Shanghai, China.
Niu Y; School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, China.
Zhang R; Department of Otolaryngology, Huadong Hospital, Fudan University, Shanghai, China. Electronic address: .
Huang Y; Department of Otolaryngology, Huadong Hospital, Fudan University, Shanghai, China.
Wang J; Department of Otolaryngology, Huadong Hospital, Fudan University, Shanghai, China.
Qiu W; Department of Respiratory Medicine, Huadong Hospital, Fudan University, Shanghai, China.
Zhang X; Department of Otolaryngology, Huadong Hospital, Fudan University, Shanghai, China.
Han Z; Department of Otolaryngology, Huadong Hospital, Fudan University, Shanghai, China.
Bao J; Department of Otolaryngology, Huadong Hospital, Fudan University, Shanghai, China.
Zhu H; Department of Respiratory Medicine, Huadong Hospital, Fudan University, Shanghai, China.
Duan Y; Shanghai Environmental Monitoring Center, Shanghai, China.
Kan H; School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, China.
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 May; Vol. 137, pp. 111261. Date of Electronic Publication: 2021 Jan 19.
Typ publikacji :
Journal Article
MeSH Terms :
Eosinophilia/*chemically induced
Eosinophils/*drug effects
Inflammation/*chemically induced
Nasal Mucosa/*drug effects
Ozone/*toxicity
Rhinitis, Allergic/*chemically induced
Rhinitis, Allergic/*immunology
Th2 Cells/*drug effects
Administration, Inhalation ; Animals ; Cytokines/metabolism ; Disease Models, Animal ; Eosinophilia/immunology ; Eosinophilia/metabolism ; Eosinophilia/pathology ; Eosinophils/immunology ; Eosinophils/metabolism ; Female ; Immunoglobulin E/blood ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Nasal Mucosa/immunology ; Nasal Mucosa/metabolism ; Nasal Mucosa/pathology ; Ovalbumin ; Ozone/administration & dosage ; Rats, Sprague-Dawley ; Rhinitis, Allergic/metabolism ; Rhinitis, Allergic/pathology ; Th2 Cells/immunology ; Th2 Cells/metabolism
Czasopismo naukowe
Tytuł :
The intersection of metformin and inflammation.
Autorzy :
Bharath LP; Department of Nutrition and Public Health, Merrimack College, North Andover, Massachusetts.
Nikolajczyk BS; Department of Pharmacology and Nutritional Sciences and Barnstable Brown Diabetes and Obesity Center, University of Kentucky, Lexington, Kentucky.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2021 May 01; Vol. 320 (5), pp. C873-C879. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Inflammation/*drug therapy
Metformin/*therapeutic use
Mitochondria/*drug effects
Mitophagy/*drug effects
Animals ; Autophagy-Related Proteins/metabolism ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Mitochondria/metabolism ; Mitochondria/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Nonclassical monocytes in cardiovascular physiology and disease.
Autorzy :
Tahir S; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich, Munich, Germany.
Steffens S; Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2021 May 01; Vol. 320 (5), pp. C761-C770. Date of Electronic Publication: 2021 Feb 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Adaptive Immunity*
Immunity, Innate*
Cardiovascular Diseases/*immunology
Endothelial Cells/*immunology
Endothelium, Vascular/*immunology
Inflammation/*immunology
Monocytes/*immunology
Animals ; Cardiovascular Diseases/metabolism ; Cardiovascular Diseases/pathology ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/pathology ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Monocytes/metabolism ; Monocytes/pathology ; Phenotype ; Signal Transduction
Czasopismo naukowe
Tytuł :
Ischemic Stroke, Inflammation, and Endotheliopathy in COVID-19 Patients.
Autorzy :
McAlpine LS; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Zubair AS; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Maran I; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Chojecka P; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Lleva P; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Jasne AS; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Navaratnam D; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Matouk C; Department of Neurosurgery (C.M.), Yale University School of Medicine, New Haven, CT.
Schindler J; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Sheth KN; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Chun H; Department of Internal Medicine, Section of Cardiovascular Medicine (H.C.), Yale University School of Medicine, New Haven, CT.
Lee AI; Department of Internal Medicine, Section of Hematology (A.I.L.), Yale University School of Medicine, New Haven, CT.
Spudich S; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Sharma R; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.
Sansing LH; Department of Neurology (L.S.M., A.S.Z., I.M., P.C., P.L., A.S.J., D.N., J.S., K.N.S., S.S., R.S., L.H.S.), Yale University School of Medicine, New Haven, CT.; Department of Immunobiology (L.H.S.), Yale University School of Medicine, New Haven, CT.
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Źródło :
Stroke [Stroke] 2021 Jun; Vol. 52 (6), pp. e233-e238. Date of Electronic Publication: 2021 May 10.
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain Ischemia/*blood
COVID-19/*blood
Endothelium, Vascular/*metabolism
Inflammation Mediators/*blood
Ischemic Stroke/*blood
Aged ; Aged, 80 and over ; Brain Ischemia/diagnosis ; Brain Ischemia/epidemiology ; COVID-19/diagnosis ; COVID-19/epidemiology ; Cohort Studies ; Endothelium, Vascular/pathology ; Humans ; Inflammation/blood ; Inflammation/diagnosis ; Inflammation/epidemiology ; Ischemic Stroke/diagnosis ; Ischemic Stroke/epidemiology ; Middle Aged ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Dysregulation of Pyruvate Kinase M2 Promotes Inflammation in a Mouse Model of Obese Allergic Asthma.
Autorzy :
Manuel AM; Department of Pathology and Department of Laboratory Medicine, and.
van de Wetering C; Department of Pathology and Department of Laboratory Medicine, and.
MacPherson M; Department of Pathology and Department of Laboratory Medicine, and.
Erickson C; Department of Pathology and Department of Laboratory Medicine, and.
Murray C; Department of Pathology and Department of Laboratory Medicine, and.
Aboushousha R; Department of Pathology and Department of Laboratory Medicine, and.
van der Velden J; Department of Pathology and Department of Laboratory Medicine, and.
Dixon AE; Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.
Poynter ME; Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.
Irvin CG; Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont.
Taatjes DJ; Department of Pathology and Department of Laboratory Medicine, and.
van der Vliet A; Department of Pathology and Department of Laboratory Medicine, and.
Anathy V; Department of Pathology and Department of Laboratory Medicine, and.
Janssen-Heininger YMW; Department of Pathology and Department of Laboratory Medicine, and.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2021 Jun; Vol. 64 (6), pp. 709-721.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Asthma/*enzymology
Asthma/*pathology
Hypersensitivity/*enzymology
Hypersensitivity/*pathology
Inflammation/*enzymology
Inflammation/*pathology
Pyruvate Kinase/*metabolism
Animals ; Asthma/complications ; Asthma/parasitology ; Bronchial Hyperreactivity/complications ; Diet, High-Fat ; Disease Models, Animal ; Enzyme Activation/drug effects ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Glutathione/metabolism ; Glycolysis ; Homeostasis/drug effects ; Hypersensitivity/complications ; Hypersensitivity/parasitology ; Inflammation Mediators/metabolism ; Lung/enzymology ; Lung/pathology ; Mice, Inbred C57BL ; Mice, Obese ; Models, Biological ; Pyridazines/administration & dosage ; Pyridazines/pharmacology ; Pyroglyphidae ; Pyrroles/administration & dosage ; Pyrroles/pharmacology
Czasopismo naukowe
Tytuł :
Pro-Inflammatory Cytokines: Potential Links between the Endocannabinoid System and the Kynurenine Pathway in Depression.
Autorzy :
Zádor F; Institute of Biochemistry, Biological Research Center, H-6726 Szeged, Hungary.
Joca S; Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark.
Nagy-Grócz G; Faculty of Health Sciences and Social Studies, University of Szeged, H-6726 Szeged, Hungary.; Albert Szent-Györgyi Clinical Center, Department of Neurology, Faculty of Medicine, University of Szeged, H-6725 Szeged, Hungary.
Dvorácskó S; Institute of Biochemistry, Biological Research Center, H-6726 Szeged, Hungary.; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Szűcs E; Institute of Biochemistry, Biological Research Center, H-6726 Szeged, Hungary.; Doctoral School of Theoretical Medicine, Faculty of Medicine, University of Szeged, H-6720 Szeged, Hungary.
Tömböly C; Institute of Biochemistry, Biological Research Center, H-6726 Szeged, Hungary.
Benyhe S; Institute of Biochemistry, Biological Research Center, H-6726 Szeged, Hungary.
Vécsei L; Albert Szent-Györgyi Clinical Center, Department of Neurology, Faculty of Medicine, University of Szeged, H-6725 Szeged, Hungary.; MTA-SZTE Neuroscience Research Group, University of Szeged, H-6725 Szeged, Hungary.; Department of Neurology, Interdisciplinary Excellence Center, University of Szeged, H-6725 Szeged, Hungary.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 31; Vol. 22 (11). Date of Electronic Publication: 2021 May 31.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cytokines/*metabolism
Depression/*etiology
Depression/*metabolism
Inflammation Mediators/*metabolism
Animals ; Biomarkers ; Depression/psychology ; Disease Susceptibility ; Endocannabinoids/metabolism ; Humans ; Inflammation/complications ; Inflammation/etiology ; Inflammation/metabolism ; Kynurenine/metabolism ; Metabolic Networks and Pathways ; Serotonin/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
The pLysRS-Ap 4 A Pathway in Mast Cells Regulates the Switch from Host Defense to a Pathological State.
Autorzy :
Govindaraj S; Department of Biochemistry and Molecular Biology, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Paruchuru LB; Department of Biochemistry and Molecular Biology, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Razin E; Department of Biochemistry and Molecular Biology, Institute for Medical Research Israel-Canada, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 25; Vol. 22 (11). Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Immunity, Innate*
Inflammation Mediators/*immunology
Mast Cells/*immunology
Signal Transduction/*immunology
Animals ; Humans ; Inflammation/immunology ; Inflammation/pathology ; Mast Cells/pathology
Czasopismo naukowe
Tytuł :
Polyphenols Extracted from Shanxi-Aged Vinegar Inhibit Inflammation in LPS-Induced RAW264.7 Macrophages and ICR Mice via the Suppression of MAPK/NF-κB Pathway Activation.
Autorzy :
Du P; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.; State Key Laboratory of Food Nutrition and Safety, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China.
Song J; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.; State Key Laboratory of Food Nutrition and Safety, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China.
Qiu H; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.; State Key Laboratory of Food Nutrition and Safety, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China.
Liu H; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.
Zhang L; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.
Zhou J; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.
Jiang S; Research Center for Modern Analysis Techniques, Tianjin University of Science & Technology, Tianjin 300457, China.
Liu J; Research Center for Modern Analysis Techniques, Tianjin University of Science & Technology, Tianjin 300457, China.
Zheng Y; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.; State Key Laboratory of Food Nutrition and Safety, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China.
Wang M; Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology), Ministry of Education, Tianjin 300457, China.; State Key Laboratory of Food Nutrition and Safety, Tianjin Engineering Research Center of Microbial Metabolism and Fermentation Process Control, College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 May 07; Vol. 26 (9). Date of Electronic Publication: 2021 May 07.
Typ publikacji :
Journal Article
MeSH Terms :
Acetic Acid/*chemistry
Inflammation/*pathology
MAP Kinase Signaling System/*drug effects
Macrophages/*pathology
NF-kappa B/*metabolism
Polyphenols/*isolation & purification
Polyphenols/*pharmacology
Animals ; Anti-Inflammatory Agents/pharmacology ; Apoptosis/drug effects ; Cell Nucleus Shape/drug effects ; Cell Shape/drug effects ; Cell Survival/drug effects ; Cytokines/metabolism ; Inflammation Mediators/metabolism ; Lipopolysaccharides ; Liver/drug effects ; Liver/pathology ; Macrophages/drug effects ; Macrophages/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Mice, Inbred ICR ; RAW 264.7 Cells
Czasopismo naukowe
Tytuł :
High glucose exacerbates neuroinflammation and apoptosis at the intermediate stage after post-traumatic brain injury.
Autorzy :
Zhang W; Department of Neurosurgery, Tangshan Gongren Hospital, Tangshan, Hebei 063000, China.; Hebei Institute of Head Trauma, Tangshan Gongren Hospital, Tangshan, Hebei 063000, China.
Hong J; Department of Neurosurgery, Tangshan Gongren Hospital, Tangshan, Hebei 063000, China.; Hebei Institute of Head Trauma, Tangshan Gongren Hospital, Tangshan, Hebei 063000, China.
Zheng W; Department of Cardiology, Tangshan Gongren Hospital, Tangshan, Hebei 063000, China.
Liu A; Department of Neurosurgery, Tangshan Gongren Hospital, Tangshan, Hebei 063000, China.; Hebei Institute of Head Trauma, Tangshan Gongren Hospital, Tangshan, Hebei 063000, China.
Yang Y; Department of Endocrinology, Tangshan Gongren Hospital, Tangshan, Hebei 063000, China.
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Źródło :
Aging [Aging (Albany NY)] 2021 Jun 27; Vol. 13 (12), pp. 16088-16104. Date of Electronic Publication: 2021 Jun 27.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Progression*
Apoptosis/*drug effects
Brain Injuries, Traumatic/*pathology
Glucose/*toxicity
Inflammation/*pathology
Neurons/*pathology
Animals ; Brain Injuries, Traumatic/physiopathology ; Cell Survival ; Cognitive Dysfunction/complications ; Cognitive Dysfunction/physiopathology ; Down-Regulation/genetics ; Hyperglycemia/complications ; Hyperglycemia/physiopathology ; Inflammation Mediators/metabolism ; MAP Kinase Kinase 5/metabolism ; MAP Kinase Signaling System ; Male ; Models, Biological ; Phosphorylation ; Rats, Sprague-Dawley ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
Effect of Fish Bone Bioactive Peptides on Oxidative, Inflammatory and Pigmentation Processes Triggered by UVB Irradiation in Skin Cells.
Autorzy :
Iosageanu A; National Institute of R&D for Biological Sciences, 296, Splaiul Independentei, 060031 Bucharest, Romania.
Ilie D; National Institute of R&D for Biological Sciences, 296, Splaiul Independentei, 060031 Bucharest, Romania.
Craciunescu O; National Institute of R&D for Biological Sciences, 296, Splaiul Independentei, 060031 Bucharest, Romania.
Seciu-Grama AM; National Institute of R&D for Biological Sciences, 296, Splaiul Independentei, 060031 Bucharest, Romania.
Oancea A; National Institute of R&D for Biological Sciences, 296, Splaiul Independentei, 060031 Bucharest, Romania.
Zarnescu O; Faculty of Biology, University of Bucharest, 91-95, Splaiul Independentei, 050095 Bucharest, Romania.
Moraru I; Laboratoarele Medica SRL, 11, Frasinului Street, 075100 Otopeni, Romania.
Oancea F; National Institute for R&D in Chemistry and Petrochemistry-Icechim, 202, Splaiul Independentei, 060021 Bucharest, Romania.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 May 04; Vol. 26 (9). Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Pigmentation*/drug effects
Pigmentation*/radiation effects
Ultraviolet Rays*
Bone and Bones/*drug effects
Inflammation/*pathology
Peptides/*pharmacology
Skin/*radiation effects
Animals ; Antioxidants/pharmacology ; Cell Survival/drug effects ; Cytokines/metabolism ; Cytoprotection/drug effects ; Cytoprotection/radiation effects ; Fishes ; HaCaT Cells/drug effects ; HaCaT Cells/radiation effects ; Humans ; Inflammation Mediators/metabolism ; Intracellular Space/metabolism ; Macrophages/drug effects ; Macrophages/metabolism ; Malondialdehyde/metabolism ; Melanins/biosynthesis ; Mice ; Molecular Weight ; Oxidation-Reduction/drug effects ; Oxidation-Reduction/radiation effects ; Peptides/isolation & purification ; Reactive Oxygen Species/metabolism ; Spectrophotometry, Ultraviolet ; THP-1 Cells
Czasopismo naukowe
Tytuł :
Luteolin alleviates inflammation and modulates gut microbiota in ulcerative colitis rats.
Autorzy :
Li B; Department of Gastroenterology, Hebei Provincial Hospital of Chinese Medicine, Shijiazhuang, Hebei, China.
Du P; Department of Gastroenterology, Hebei Provincial Hospital of Chinese Medicine, Shijiazhuang, Hebei, China.
Du Y; Department of Gastroenterology, Hebei Provincial Hospital of Chinese Medicine, Shijiazhuang, Hebei, China.
Zhao D; Department of Gastroenterology, Hebei Provincial Hospital of Chinese Medicine, Shijiazhuang, Hebei, China.
Cai Y; Department of Gastroenterology, Hebei Provincial Hospital of Chinese Medicine, Shijiazhuang, Hebei, China.
Yang Q; Department of Gastroenterology, Hebei Provincial Hospital of Chinese Medicine, Shijiazhuang, Hebei, China. Electronic address: .
Guo Z; Department of Hematology, Hebei Provincial Hospital of Chinese Medicine, Shijiazhuang, Hebei, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Mar 15; Vol. 269, pp. 119008. Date of Electronic Publication: 2021 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
Gastrointestinal Microbiome*/drug effects
Colitis, Ulcerative/*drug therapy
Colitis, Ulcerative/*microbiology
Inflammation/*drug therapy
Inflammation/*microbiology
Luteolin/*therapeutic use
Animals ; Bacteria/classification ; Colitis, Ulcerative/complications ; Colon/pathology ; Discriminant Analysis ; Inflammation/complications ; Inflammation Mediators/metabolism ; Luteolin/pharmacology ; Male ; Principal Component Analysis ; Rats, Wistar
Czasopismo naukowe
Tytuł :
New Perspectives in the Study of Intestinal Inflammation: Focus on the Resolution of Inflammation.
Autorzy :
Camba-Gómez M; Molecular and Cellular Gastroenterology, Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.
Gualillo O; SERGAS (Servizo Galego de Saúde) and IDIS (Instituto de Investigación Sanitaria de Santiago), The NEIRID Lab (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases), Research Laboratory 9, Santiago University Clinical Hospital, 15706 Santiago de Compostela, Spain.
Conde-Aranda J; Molecular and Cellular Gastroenterology, Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 05; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Inflammation/*pathology
Intestines/*pathology
Animals ; Chronic Disease ; Humans ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Inflammatory Bowel Diseases/metabolism ; Inflammatory Bowel Diseases/pathology
Czasopismo naukowe
Tytuł :
Formyl Peptide Receptor (FPR)1 Modulation by Resveratrol in an LPS-Induced Neuroinflammatory Animal Model.
Autorzy :
Calvello R; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, I-70125 Bari, Italy.
Cianciulli A; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, I-70125 Bari, Italy.
Porro C; Department of Clinical and Experimental Medicine, University of Foggia, I-71100 Foggia, Italy.
Moda P; Nuclear Medicine Department, SS. Annunziata Hospital, I-74100 Taranto, Italy.
De Nuccio F; Department of Biological and Environmental Sciences and Technologies, Section of Human Anatomy, University of Salento, I-73100 Lecce, Italy.
Nicolardi G; Department of Biological and Environmental Sciences and Technologies, Section of Human Anatomy, University of Salento, I-73100 Lecce, Italy.
Giannotti L; Department of Biological and Environmental Sciences and Technologies, Section of Human Anatomy, University of Salento, I-73100 Lecce, Italy.
Panaro MA; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, I-70125 Bari, Italy.
Lofrumento DD; Department of Biological and Environmental Sciences and Technologies, Section of Human Anatomy, University of Salento, I-73100 Lecce, Italy.
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Źródło :
Nutrients [Nutrients] 2021 Apr 23; Vol. 13 (5). Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article
MeSH Terms :
Astrocytes/*pathology
Inflammation/*metabolism
Inflammation/*pathology
Microglia/*pathology
Receptors, Formyl Peptide/*metabolism
Resveratrol/*pharmacology
Animals ; Anti-Inflammatory Agents/pharmacology ; Astrocytes/drug effects ; Astrocytes/metabolism ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/metabolism ; Disease Models, Animal ; Glial Fibrillary Acidic Protein/metabolism ; Inflammation/chemically induced ; Inflammation Mediators/metabolism ; Interleukin 1 Receptor Antagonist Protein/metabolism ; Lipopolysaccharides ; Male ; Mice ; Microfilament Proteins/genetics ; Microfilament Proteins/metabolism ; Microglia/drug effects ; Microglia/metabolism ; Models, Biological ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Signal Transduction ; Sirtuin 1/genetics ; Sirtuin 1/metabolism ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
β-Sitosterol Circumvents Obesity Induced Inflammation and Insulin Resistance by down-Regulating IKKβ/NF-κB and JNK Signaling Pathway in Adipocytes of Type 2 Diabetic Rats.
Autorzy :
Jayaraman S; Department of Biochemistry, Saveetha Institute of Medical and Technical Sciences, Saveetha Dental College and Hospitals, Saveetha University, Chennai, Tamil Nadu 600077, India.
Devarajan N; Central Research Laboratory, Meenakshi Ammal Dental College, Meenakshi Academy of Higher Education and Research, Maduravoyal, Chennai, Tamil Nadu 600095, India.
Rajagopal P; Central Research Laboratory, Meenakshi Academy of Higher Education and Research, Chennai, Tamil Nadu 600078, India.
Babu S; Department of Biochemistry, Saveetha Institute of Medical and Technical Sciences, Saveetha Dental College and Hospitals, Saveetha University, Chennai, Tamil Nadu 600077, India.
Ganesan SK; Structural Biology & Bioinformatics Division, TRUE Campus, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
Veeraraghavan VP; Department of Biochemistry, Saveetha Institute of Medical and Technical Sciences, Saveetha Dental College and Hospitals, Saveetha University, Chennai, Tamil Nadu 600077, India.
Palanisamy CP; State Key Laboratory of Biobased Materials and Green Papermaking, College of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Science, Jinan 250353, China.
Cui B; State Key Laboratory of Biobased Materials and Green Papermaking, College of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Science, Jinan 250353, China.
Periyasamy V; Department of Biotechnology and Bioinformatics, Holy Cross College, Trichy, Tamil Nadu 620002, India.
Chandrasekar K; Department of Anatomy, All India Institute of Medical Sciences, Nagpur, Maharashtra 440025, India.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Apr 06; Vol. 26 (7). Date of Electronic Publication: 2021 Apr 06.
Typ publikacji :
Journal Article
MeSH Terms :
Down-Regulation*/drug effects
Insulin Resistance*
Adipocytes/*metabolism
Diabetes Mellitus, Type 2/*complications
I-kappa B Kinase/*metabolism
Inflammation/*drug therapy
Obesity/*complications
Sitosterols/*therapeutic use
Adipocytes/drug effects ; Adipokines/blood ; Adipose Tissue/drug effects ; Adipose Tissue/metabolism ; Adipose Tissue/pathology ; Animals ; Body Weight/drug effects ; Cytokines/blood ; Cytokines/genetics ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/pathology ; Diet, High-Fat ; Feeding Behavior ; Inflammation/blood ; Inflammation/metabolism ; Inflammation/pathology ; Inflammation Mediators/metabolism ; MAP Kinase Signaling System/drug effects ; Male ; Molecular Docking Simulation ; NF-kappa B/metabolism ; Obesity/blood ; PPAR gamma/genetics ; PPAR gamma/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Sitosterols/pharmacology ; Sterol Regulatory Element Binding Protein 1/metabolism ; Sucrose ; Up-Regulation/drug effects ; Up-Regulation/genetics
Czasopismo naukowe

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