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Tytuł :
LinkedImm: a linked data graph database for integrating immunological data.
Autorzy :
Bukhari SAC; Division of Computer Science, Mathematics and Science, Collins College of Professional Studies, St. John's University, New York, NY, USA.
Pawar S; Department of Genetics, Yale School of Medicine, New Haven, CT, USA.
Mandell J; Program in Computational Biology and Bioinformatics, Yale School of Medicine, New Haven, CT, USA.
Kleinstein SH; Program in Computational Biology and Bioinformatics, Yale School of Medicine, New Haven, CT, USA.; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
Cheung KH; Program in Computational Biology and Bioinformatics, Yale School of Medicine, New Haven, CT, USA. .; Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA. .; Yale Center for Medical Informatics, Yale School of Medicine, New Haven, CT, USA. .
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Źródło :
BMC bioinformatics [BMC Bioinformatics] 2021 Aug 25; Vol. 22 (Suppl 9), pp. 105. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
Information Storage and Retrieval*
Semantic Web*
Databases, Factual ; Language ; Systems Biology
Czasopismo naukowe
Tytuł :
Toward a systematic conflict resolution framework for ontologies.
Autorzy :
Keet CM; Department of Computer Science, University of Cape Town, 18 University Avenue, Cape Town, 7700, South Africa.
Grütter R; Swiss Federal Research Institute WSL, Zürcherstrasse 111, Birmensdorf, CH-8903, Switzerland. .
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Źródło :
Journal of biomedical semantics [J Biomed Semantics] 2021 Aug 09; Vol. 12 (1), pp. 15. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Semantic Web*
Semantics*
Vocabulary, Controlled*
Biological Ontologies/*statistics & numerical data
Computational Biology/*statistics & numerical data
Information Storage and Retrieval/*statistics & numerical data
COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/virology ; Computational Biology/methods ; Databases, Factual/statistics & numerical data ; Epidemics/prevention & control ; Humans ; Information Storage and Retrieval/methods ; Logic ; SARS-CoV-2/physiology
Czasopismo naukowe
Tytuł :
Molecular-level similarity search brings computing to DNA data storage.
Autorzy :
Bee C; Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA, USA.
Chen YJ; Microsoft Research, Redmond, WA, USA.
Queen M; Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA, USA.
Ward D; Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA, USA.
Liu X; Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA, USA.
Organick L; Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA, USA.
Seelig G; Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA, USA.; Department of Electrical & Computer Engineering, University of Washington, Seattle, WA, USA.
Strauss K; Microsoft Research, Redmond, WA, USA. .
Ceze L; Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, WA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 06; Vol. 12 (1), pp. 4764. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Databases, Genetic*
Information Storage and Retrieval*
Computational Biology/*methods
DNA/*chemistry
Algorithms ; Base Sequence ; Computer Simulation ; DNA/genetics ; DNA Probes ; Databases, Factual ; Neural Networks, Computer
Czasopismo naukowe
Tytuł :
Scool: a new data storage format for single-cell Hi-C data.
Autorzy :
Wolff J; Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg 79110, Germany.
Abdennur N; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Backofen R; Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg 79110, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg 79104, Germany.
Grüning B; Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg 79110, Germany.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2021 Aug 04; Vol. 37 (14), pp. 2053-2054.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Information Storage and Retrieval*
Software*
Czasopismo naukowe
Tytuł :
Exploring Chemical Information in PubChem.
Autorzy :
Kim S; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland.
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Źródło :
Current protocols [Curr Protoc] 2021 Aug; Vol. 1 (8), pp. e217.
Typ publikacji :
Journal Article
MeSH Terms :
Databases, Chemical*
Information Storage and Retrieval*
Biological Assay ; Databases, Factual ; Proteins ; United States
Czasopismo naukowe
Tytuł :
[Comparative Analysis of Three Massive Medical Image Storage Technologies].
Autorzy :
Gao J; Medical Image Laboratory of Shanghai Institute of Technical Physics, Chinese Academy of Sciences, Shanghai, 200083.; Unversity of Chinese Academy of Sciences, Beijing, 100049.
Yang Y; Medical Image Laboratory of Shanghai Institute of Technical Physics, Chinese Academy of Sciences, Shanghai, 200083.
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Źródło :
Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation [Zhongguo Yi Liao Qi Xie Za Zhi] 2021 Jul 30; Vol. 45 (4), pp. 366-371.
Typ publikacji :
Journal Article
MeSH Terms :
Cloud Computing*
Information Storage and Retrieval*
Computer Communication Networks ; Humans ; Technology
Czasopismo naukowe
Tytuł :
Online Interactive Platform for COVID-19 Literature Visual Analytics: Platform Development Study.
Autorzy :
Moran A; Pacific Northwest National Laboratory, Richland, WA, United States.
Hampton S; Pacific Northwest National Laboratory, Richland, WA, United States.
Dowson S; Pacific Northwest National Laboratory, Richland, WA, United States.
Dagdelen J; Lawrence Berkeley National Laboratory, Berkeley, CA, United States.; Department of Materials Science and Engineering, University of California, Berkeley, Berkeley, CA, United States.
Trewartha A; Lawrence Berkeley National Laboratory, Berkeley, CA, United States.
Ceder G; Lawrence Berkeley National Laboratory, Berkeley, CA, United States.; Department of Materials Science and Engineering, University of California, Berkeley, Berkeley, CA, United States.
Persson K; Lawrence Berkeley National Laboratory, Berkeley, CA, United States.; Department of Materials Science and Engineering, University of California, Berkeley, Berkeley, CA, United States.
Saxon E; Pacific Northwest National Laboratory, Richland, WA, United States.
Barker A; Pacific Northwest National Laboratory, Richland, WA, United States.
Charles L; Pacific Northwest National Laboratory, Richland, WA, United States.
Webb-Robertson BJ; Pacific Northwest National Laboratory, Richland, WA, United States.
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Źródło :
Journal of medical Internet research [J Med Internet Res] 2021 Jul 16; Vol. 23 (7), pp. e26995. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*
Image Interpretation, Computer-Assisted*
Information Storage and Retrieval*
SARS-CoV-2*
Humans ; Natural Language Processing ; Software ; User-Computer Interface
Czasopismo naukowe
Tytuł :
Hough Transform-Based Angular Features for Learning-Free Handwritten Keyword Spotting.
Autorzy :
Kundu S; Department of Electronics and Communication Engineering, National Institute of Technology Durgapur, Durgapur 713209, India.
Malakar S; Department of Computer Science, Asutosh College, Kolkata 700026, India.
Geem ZW; College of IT Convergence, Gachon University, 1342 Seongnam Daero, Seongnam 13120, Korea.
Moon YY; College of IT Convergence, Gachon University, 1342 Seongnam Daero, Seongnam 13120, Korea.
Singh PK; Department of Information Technology, Jadavpur University, Kolkata 700106, India.
Sarkar R; Department of Computer Science and Engineering, Jadavpur University, Kolkata 700032, India.
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Źródło :
Sensors (Basel, Switzerland) [Sensors (Basel)] 2021 Jul 07; Vol. 21 (14). Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Information Storage and Retrieval*
Handwriting ; Humans
Czasopismo naukowe
Tytuł :
Gender Equality and Female Offending: Evidence From International Data Sources.
Autorzy :
Chu DC; National Chung Cheng University, Minhsiung, Chia Yi, Taiwan.
Hebenton B; University of Manchester, UK.
Toh A; University of Arkansas, Pine Bluff, USA.
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Źródło :
International journal of offender therapy and comparative criminology [Int J Offender Ther Comp Criminol] 2021 Oct; Vol. 65 (13-14), pp. 1496-1519. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article
MeSH Terms :
Gender Equity*
Information Storage and Retrieval*
Europe ; Female ; Humans
Czasopismo naukowe
Tytuł :
EUROlinkCAT protocol for a European population-based data linkage study investigating the survival, morbidity and education of children with congenital anomalies.
Autorzy :
Morris JK; Population Health Research Institute, St George's University of London, London, UK .
Garne E; Paediatric Department, Hospital Lillebaelt, Kolding, Denmark.
Loane M; Faculty of Life and Health Sciences, Ulster University, Coleraine, UK.
Barisic I; Children's Hospital Zagreb, Centre of Excellence for Reproductive and Regenerative Medicine, Medical School University of Zagreb, Zagreb, Croatia.
Densem J; Biomedical Computing Limited, Battle, UK.
Latos-Bieleńska A; Polish Registry of Congenital Malformations, Chair and Department of Medical Genetics, Poznan University of Medical Sciences, Poznan, Poland.
Neville A; IMER Registry (Emila Romagna Registry of Birth Defects), University Hospital of Ferrara, Emilia-Romagna, Italy.
Pierini A; Instituto di Fisiologia Clinica, Consiglio Nazionale delle Ricerche, Pisa, Italy.
Rankin J; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, Tyne and Wear, UK.
Rissmann A; Malformation Monitoring Centre Saxony-Anhalt, Otto von Guericke University Medical Faculty, Magdeburg, Germany.
de Walle H; Department of Genetics, University Medical Centre Groningen, Groningen, The Netherlands.
Tan J; Population Health Research Institute, St George's University of London, London, UK.
Given JE; Faculty of Life and Health Sciences, Ulster University, Coleraine, UK.
Claridge H; Population Health Research Institute, St George's University of London, London, UK.
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Corporate Authors :
EUROlinkCAT Consortium
Źródło :
BMJ open [BMJ Open] 2021 Jun 28; Vol. 11 (6), pp. e047859. Date of Electronic Publication: 2021 Jun 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Congenital Abnormalities*/epidemiology
Information Storage and Retrieval*
Child ; Databases, Factual ; Europe/epidemiology ; Humans ; Infant ; Morbidity ; Registries
Czasopismo naukowe
Tytuł :
Mapping chronic disease prevalence based on medication use and socio-demographic variables: an application of LASSO on administrative data sources in healthcare in the Netherlands.
Autorzy :
Füssenich K; RIVM (National Institute for Public Health and the Environment), Centre for Nutrition, Prevention and Health Services, P.O. Box 1, 3720, BA, Bilthoven, The Netherlands. .; Groningen University, UMCG, Department of Epidemiology, Groningen, The Netherlands. .; Capaciteitsorgaan (Council for Medical Manpower Planning), Utrecht, The Netherlands. .
Boshuizen HC; RIVM (National Institute for Public Health and the Environment), Centre for Nutrition, Prevention and Health Services, P.O. Box 1, 3720, BA, Bilthoven, The Netherlands.; Wageningen University and Research, Biometris, Wageningen, The Netherlands.
Nielen MMJ; RIVM (National Institute for Public Health and the Environment), Centre for Health and Society, Bilthoven, The Netherlands.; NIVEL (Netherlands Institute for Health Srvices Research), Utrecht, The Netherlands.
Buskens E; Groningen University, UMCG, Department of Epidemiology, Groningen, The Netherlands.; Groningen University, Faculty of Economics and Business, Groningen, The Netherlands.
Feenstra TL; RIVM (National Institute for Public Health and the Environment), Centre for Nutrition, Prevention and Health Services, P.O. Box 1, 3720, BA, Bilthoven, The Netherlands.; Groningen University, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Groningen, The Netherlands.
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Źródło :
BMC public health [BMC Public Health] 2021 Jun 02; Vol. 21 (1), pp. 1039. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Delivery of Health Care*
Information Storage and Retrieval*
Chronic Disease ; Humans ; Netherlands/epidemiology ; Prevalence
Czasopismo naukowe
Tytuł :
[Routine Practice Data for Evaluating Intervention Effects: Part 2 of the Manual].
Autorzy :
Hoffmann F; Department für Versorgungsforschung, Carl von Ossietzky Universität Oldenburg, Oldenburg.
Kaiser T; Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG), Köln.
Apfelbacher C; Institut für Sozialmedizin und Gesundheitssystemforschung, Otto von Guericke Universität Magdeburg, Magdeburg.
Benz S; Kliniken Böblingen, Klinikverbund Südwest GmbH, Sindelfingen.; Arbeitsgemeinschaft Deutscher Tumorzentren, Berlin.
Bierbaum T; Deutsches Netzwerk Versorgungsforschung e.V., Berlin.
Dreinhöfer K; Klinik für Orthopädie und Unfallchirurgie, Medical Park Berlin Humboldtmühle.; Centrum für Muskuloskeletale Chirurgie (CMSC), Charité Universitätsmedizin Berlin.
Hauptmann M; Institut für Biometrie und Registerforschung, Fakultät für Gesundheitswissenschaften, Medizinische Hochschule Brandenburg Theodor Fontane, Neuruppin.
Heidecke CD; Institut für Qualitätssicherung und Transparenz im Gesundheitswesen (IQTIG), Berlin.
Koller M; Zentrum für Klinische Studien, Universitätsklinikum Regensburg, Regensburg.
Kostuj T; Orthopädisch-Traumatologische Zentrum, St. Marien-Hospitals Hamm, Hamm.
Ortmann O; Klinik für Frauenheilkunde und Geburtshilfe, Universität Regensburg Fakultät für Medizin, Regensburg.
Schmitt J; Zentrum für Evidenzbasierte Gesundheitsversorgung, Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden, Dresden.
Schünemann H; Cochrane Canada and Mc Master GRADE Centre, WHO Collaborating Centre for Infectious Diseases, Research and Methods, Hamilton, Canada.
Veit C; BQS Institut für Qualität & Patientensicherheit GmbH, Hamburg.
Hoffmann W; Institut für Community Medicine, Universität Greifswald, Greifswald.
Klinkhammer-Schalke M; Deutsches Netzwerk Versorgungsforschung e.V., Berlin.; Tumorzentrum Regensburg, Institut für Qualitätssicherung und Versorgungsforschung, Universität Regensburg, Regensburg.
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Transliterated Title :
Versorgungsnahe Daten zur Evaluation von Interventionseffekten: Teil 2 des Manuals.
Źródło :
Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) [Gesundheitswesen] 2021 Jun; Vol. 83 (6), pp. 470-480. Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article
MeSH Terms :
Health Services Research*
Information Storage and Retrieval*
Data Collection ; Germany
Czasopismo naukowe
Tytuł :
A Recommender System to Help Refining Clinical Research Studies.
Autorzy :
Almeida JR; DETI/IEETA, University of Aveiro, Portugal.; Department of Computation, University of A Coruña, Spain.
Silva JF; DETI/IEETA, University of Aveiro, Portugal.
Matos S; DETI/IEETA, University of Aveiro, Portugal.
Pazos A; Department of Computation, University of A Coruña, Spain.
Oliveira JL; DETI/IEETA, University of Aveiro, Portugal.
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Źródło :
Studies in health technology and informatics [Stud Health Technol Inform] 2021 May 27; Vol. 281, pp. 327-331.
Typ publikacji :
Journal Article
MeSH Terms :
Information Storage and Retrieval*
Search Engine*
Cohort Studies
Czasopismo naukowe
Tytuł :
i2b2 to Optimize Patients Enrollment.
Autorzy :
Bucalo M; BIOMERIS (BIOMEdical Research Informatics Solutions), Pavia, Italy.
Gabetta M; BIOMERIS (BIOMEdical Research Informatics Solutions), Pavia, Italy.
Chiudinelli L; Hospital 'ASST Papa Giovanni XXIII', Bergamo, Italy.
Larizza C; Laboratory for Biomedical Informatics, University of Pavia, Italy.
Bellasi A; Hospital 'ASST Papa Giovanni XXIII', Bergamo, Italy.
Zambelli A; Hospital 'ASST Papa Giovanni XXIII', Bergamo, Italy.
Barbarini N; Hospital 'ASST Papa Giovanni XXIII', Bergamo, Italy.
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Źródło :
Studies in health technology and informatics [Stud Health Technol Inform] 2021 May 27; Vol. 281, pp. 506-507.
Typ publikacji :
Journal Article
MeSH Terms :
Data Warehousing*
Information Storage and Retrieval*
Humans
Czasopismo naukowe
Tytuł :
Distributed Skin Lesion Analysis Across Decentralised Data Sources.
Autorzy :
Mou Y; RWTH Aachen University, Germany.
Welten S; RWTH Aachen University, Germany.
Jaberansary M; RWTH Aachen University, Germany.
Ucer Yediel Y; Fraunhofer Institute for Applied Information Technology (FIT), Germany.
Kirsten T; Hochschule Mittweida, Germany.
Decker S; RWTH Aachen University, Germany.; Fraunhofer Institute for Applied Information Technology (FIT), Germany.
Beyan O; RWTH Aachen University, Germany.; Fraunhofer Institute for Applied Information Technology (FIT), Germany.
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Źródło :
Studies in health technology and informatics [Stud Health Technol Inform] 2021 May 27; Vol. 281, pp. 352-356.
Typ publikacji :
Journal Article
MeSH Terms :
Information Storage and Retrieval*
Machine Learning*
Algorithms ; Germany ; Privacy
Czasopismo naukowe
Tytuł :
Characterization and selection of Japanese electronic health record databases used as data sources for non-interventional observational studies.
Autorzy :
Wakabayashi Y; Integrated Center for Advanced Medical Technologies, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku, Kochi, 783-8505, Japan. .
Eitoku M; Department of Environmental Medicine, Kochi Medical School, Kochi University, Kochi, Japan.
Suganuma N; Department of Environmental Medicine, Kochi Medical School, Kochi University, Kochi, Japan.
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Źródło :
BMC medical informatics and decision making [BMC Med Inform Decis Mak] 2021 May 22; Vol. 21 (1), pp. 167. Date of Electronic Publication: 2021 May 22.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Electronic Health Records*
Information Storage and Retrieval*
Humans ; Japan ; Prospective Studies ; Retrospective Studies
Czasopismo naukowe
Tytuł :
MEDLINE search retrieval issues: A longitudinal query analysis of five vendor platforms.
Autorzy :
Burns CS; School of Information Science, University of Kentucky, Lexington, Kentucky, United States of America.
Nix T; Taubman Health Sciences Library, University of Michigan, Ann Arbor, Michigan, United States of America.
Shapiro RM 2nd; Robert M. Fales Health Sciences Library - SEAHEC Medical Library, South East Area Health Education Center, Wilmington, North Carolina, United States of America.
Huber JT; School of Information Science, University of Kentucky, Lexington, Kentucky, United States of America.
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Źródło :
PloS one [PLoS One] 2021 May 06; Vol. 16 (5), pp. e0234221. Date of Electronic Publication: 2021 May 06 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Information Storage and Retrieval*/methods
MEDLINE*
Biomedical Research ; Humans ; Search Engine/methods
Czasopismo naukowe
Tytuł :
COnVIDa: COVID-19 multidisciplinary data collection and dashboard.
Autorzy :
Martínez Beltrán ET; Department of Information and Communications Engineering, University of Murcia, Murcia 30100, Spain. Electronic address: .
Quiles Pérez M; Department of Information and Communications Engineering, University of Murcia, Murcia 30100, Spain. Electronic address: .
Pastor-Galindo J; Department of Information and Communications Engineering, University of Murcia, Murcia 30100, Spain. Electronic address: .
Nespoli P; Department of Information and Communications Engineering, University of Murcia, Murcia 30100, Spain. Electronic address: .
García Clemente FJ; Department of Computer Engineering, University of Murcia, Murcia 30100, Spain. Electronic address: .
Gómez Mármol F; Department of Information and Communications Engineering, University of Murcia, Murcia 30100, Spain. Electronic address: .
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Źródło :
Journal of biomedical informatics [J Biomed Inform] 2021 May; Vol. 117, pp. 103760. Date of Electronic Publication: 2021 Mar 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*
Data Collection*
Information Storage and Retrieval*
Humans ; Pandemics
Czasopismo naukowe
Tytuł :
The Certainty Framework for Assessing Real-World Data in Studies of Medical Product Safety and Effectiveness.
Autorzy :
Cocoros NM; Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.
Arlett P; Data Analytics and Methods Task Force, European Medicines Agency, Amsterdam, The Netherlands.; London School of Hygiene and Tropic Medicine, London, UK.
Dreyer NA; Center for Advanced Evidence Generation, IQVIA Real World Solutions, Cambridge, Massachusetts, USA.
Ishiguro C; Division of Epidemiology, Office of Medical Informatics and Epidemiology, Pharmaceuticals and Medical Devices Agency, Tokyo, Japan.
Iyasu S; Center for Observational and Real-world Evidence, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Sturkenboom M; Julius Center, Global Health, University Medical Center Utrecht, Utrecht, The Netherlands.
Zhou W; Center for Observational and Real-world Evidence, Merck & Co., Inc., Kenilworth, New Jersey, USA.
Toh S; Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.
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Źródło :
Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 May; Vol. 109 (5), pp. 1189-1196. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article
MeSH Terms :
Algorithms*
Information Storage and Retrieval*
Research Design*
Antiviral Agents/therapeutic use ; Data Analysis ; Humans ; Influenza, Human/drug therapy ; Influenza, Human/mortality ; Oseltamivir/therapeutic use ; Rivaroxaban/adverse effects ; Rivaroxaban/therapeutic use
Czasopismo naukowe

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