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Tytuł :
Genetic mapping of novel modifiers for Apc induced intestinal polyps' development using the genetic architecture power of the collaborative cross mice.
Autorzy :
Dorman A; Department of Clinical Microbiology & Immunology, Sackler Faculty of Medicine, Ramat Aviv, 69978, Tel-Aviv, Israel.
Binenbaum I; Department of Biology, University of Patras, Patras, Greece.; Center of Systems Biology, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
Abu-Toamih Atamni HJ; Department of Clinical Microbiology & Immunology, Sackler Faculty of Medicine, Ramat Aviv, 69978, Tel-Aviv, Israel.
Chatziioannou A; Center of Systems Biology, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
Tomlinson I; Cancer Research UK Edinburgh Centre, Charles and Ethel Barr Chair of Cancer Research, University of Edinburgh, Edinburgh, UK.
Mott R; Department of Genetics, University Collage of London, London, UK.
Iraqi FA; Department of Clinical Microbiology & Immunology, Sackler Faculty of Medicine, Ramat Aviv, 69978, Tel-Aviv, Israel. .
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Źródło :
BMC genomics [BMC Genomics] 2021 Jul 22; Vol. 22 (1), pp. 566. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Adenomatous Polyposis Coli*/genetics
Collaborative Cross Mice*
Animals ; Female ; Intestinal Polyps/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Quantitative Trait Loci
Czasopismo naukowe
Tytuł :
Immune response to dermatomyositis-specific autoantigen, transcriptional intermediary factor 1γ can result in experimental myositis.
Autorzy :
Okiyama N; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan .
Ichimura Y; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Shobo M; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Tanaka R; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Kubota N; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Saito A; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Ishitsuka Y; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.; Department of Integrative Medicine for Allergic and Immunological Disease, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
Watanabe R; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.; Department of Integrative Medicine for Allergic and Immunological Disease, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
Fujisawa Y; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Nakamura Y; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Murakami A; Medical and Biological Laboratories Co Ltd, Nagoya, Aichi, Japan.
Kayama H; Institute for Advanced Co-Creation Studies, Osaka University, Suita, Osaka, Japan.
Takeda K; Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
Fujimoto M; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.; Department of Dermatology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
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Źródło :
Annals of the rheumatic diseases [Ann Rheum Dis] 2021 Sep; Vol. 80 (9), pp. 1201-1208. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mice*
CD4-Positive T-Lymphocytes/*immunology
CD8-Positive T-Lymphocytes/*immunology
Dermatomyositis/*immunology
Nervous System Autoimmune Disease, Experimental/*immunology
Transcription Factors/*immunology
Adoptive Transfer ; Animals ; CD4-Positive T-Lymphocytes/transplantation ; CD8-Positive T-Lymphocytes/transplantation ; Humans ; Immunization ; Immunoglobulin G/immunology ; Immunoglobulin mu-Chains/genetics ; Janus Kinase Inhibitors/pharmacology ; Mice, Knockout ; Perforin/genetics ; Piperidines/pharmacology ; Pyrimidines/pharmacology ; Receptor, Interferon alpha-beta/genetics ; T-Lymphocytes/immunology ; beta 2-Microglobulin/genetics
Czasopismo naukowe
Tytuł :
Heritability of fat distributions in male mice from the founder strains of the Diversity Outbred mouse population.
Autorzy :
Keenan BT; Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Webster JC; Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Wiemken AS; Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Lavi-Romer N; Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Nguyen T; Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Svenson KL; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Galante RJ; Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Churchill GA; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Pickup S; Department of Radiology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Pack AI; Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Schwab RJ; Division of Sleep Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
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Źródło :
G3 (Bethesda, Md.) [G3 (Bethesda)] 2021 May 07; Vol. 11 (5).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Collaborative Cross Mice*
Animals ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Inbred NOD ; Mice, Inbred Strains ; Phenotype
Czasopismo naukowe
Tytuł :
Interrogating preclinical study of liposomes: The effect of mouse strain reexamined.
Autorzy :
Guan J; MOE Key Laboratory of Smart Drug Delivery, School of Pharmacy & State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 201203, PR China; Department of Pharmacology, School of Basic Medical Sciences & Center of Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University, Shanghai 200032, PR China; Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai 200040, PR China.
Wu E; MOE Key Laboratory of Smart Drug Delivery, School of Pharmacy & State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 201203, PR China.
Jin P; Department of Pharmacology, School of Basic Medical Sciences & Center of Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University, Shanghai 200032, PR China.
Hou S; Department of Pharmacology, School of Basic Medical Sciences & Center of Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University, Shanghai 200032, PR China.
Qian J; MOE Key Laboratory of Smart Drug Delivery, School of Pharmacy & State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 201203, PR China. Electronic address: .
Lu W; MOE Key Laboratory of Smart Drug Delivery, School of Pharmacy & State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 201203, PR China.
Yu B; Department of General Surgery, Shanghai Pudong Hospital, Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai 201399, PR China.
Zhan C; MOE Key Laboratory of Smart Drug Delivery, School of Pharmacy & State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 201203, PR China; Department of Pharmacology, School of Basic Medical Sciences & Center of Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University, Shanghai 200032, PR China. Electronic address: .
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Źródło :
Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2021 Jun 10; Vol. 334, pp. 178-187. Date of Electronic Publication: 2021 Apr 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Liposomes*
Mice, Inbred Strains*
Phagocytosis*
Animals ; Folic Acid ; Mice ; Mononuclear Phagocyte System
Czasopismo naukowe
Tytuł :
Establishment and histopathological study of patient-derived xenograft models and primary cell lines of epithelioid malignant peritoneal mesothelioma.
Autorzy :
Yang ZR; Department of Peritoneal Cancer Surgery, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing 100038, China.
Chen ZG; Thorgene Co., Ltd., Yizhuang Biomedical Park, Daxing District, Beijing, Beijing, China.
Ji ZH; Department of Peritoneal Cancer Surgery, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing 100038, China.
Lin YL; Department of Peritoneal Cancer Surgery, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing 100038, China.
Zhang J; Department of Peritoneal Cancer Surgery, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing 100038, China.
Ma R; Department of Peritoneal Cancer Surgery, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing 100038, China.
Li Z; Department of Pathology, Beijing Shijitan Hospital, Capital Medical University, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing, China.
Jiang X; Department of Pathology, Beijing Shijitan Hospital, Capital Medical University, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing, China.
Chen Q; Thorgene Co., Ltd., Yizhuang Biomedical Park, Daxing District, Beijing, Beijing, China.
Du XM; Department of Pathology, Beijing Shijitan Hospital, Capital Medical University, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing, China.
Li Y; Department of Peritoneal Cancer Surgery, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing 100038, China.; Department of Pathology, Beijing Shijitan Hospital, Capital Medical University, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing, China.
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Źródło :
Experimental animals [Exp Anim] 2021 May 13; Vol. 70 (2), pp. 225-235. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article
MeSH Terms :
Mice*
Cell Line, Tumor/*pathology
Heterografts/*pathology
Mesothelioma, Malignant/*pathology
Peritoneal Diseases/*pathology
Animals ; Disease Models, Animal ; Epithelioid Cells/pathology ; Female ; Humans ; Male ; Mice, Nude ; Middle Aged
Czasopismo naukowe
Tytuł :
C1qa deficiency in mice increases susceptibility to mouse hepatitis virus A59 infection.
Autorzy :
Kim HW; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.; Regenerative Dental Medicine Institute, Hysensbio, Gwacheon 13814, Korea.
Seo SM; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
Kim JY; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.; Green Cross Corporation, Yongin 16924, Korea.
Lee JH; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Choi YK; Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea. .
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Źródło :
Journal of veterinary science [J Vet Sci] 2021 May; Vol. 22 (3), pp. e36.
Typ publikacji :
Journal Article
MeSH Terms :
Complement Pathway, Classical*
Mice*
Complement C1q/*deficiency
Coronavirus Infections/*veterinary
Disease Susceptibility/*veterinary
Hepatitis, Viral, Animal/*genetics
Murine hepatitis virus/*physiology
Rodent Diseases/*genetics
Animals ; Coronavirus Infections/genetics ; Disease Susceptibility/virology ; Genetic Predisposition to Disease ; Mice, Knockout
Czasopismo naukowe
Tytuł :
Efficient production of immunodeficient non-obese diabetic/Shi-scid IL2r γ mice via the superovulation technique using inhibin antiserum and gonadotropin. mice via the superovulation technique using inhibin antiserum and gonadotropin.
Autorzy :
Goto M; 13565Central Institute for Experimental Animals (CIEA), Japan.; Center for Animal Resources and Development (CARD), Kumamoto University, Japan.
Takeo T; Center for Animal Resources and Development (CARD), Kumamoto University, Japan.
Takahashi R; 13565Central Institute for Experimental Animals (CIEA), Japan.
Nakagata N; Center for Animal Resources and Development (CARD), Kumamoto University, Japan.
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Źródło :
Laboratory animals [Lab Anim] 2021 Feb; Vol. 55 (1), pp. 13-20. Date of Electronic Publication: 2020 Jun 06.
Typ publikacji :
Journal Article
MeSH Terms :
Mice*
Superovulation*
Breeding/*methods
Gonadotropins, Equine/*chemistry
Immune Sera/*chemistry
Inhibins/*chemistry
Animals ; Female ; Male ; Mice, Inbred NOD ; Mice, SCID
Czasopismo naukowe
Tytuł :
Holdemanella biformis improves glucose tolerance and regulates GLP-1 signaling in obese mice.
Autorzy :
Romaní-Pérez M; Microbial Ecology, Nutrition and Health Research Unit, Institute of Agrochemistry and Food Technology, National Research Council (IATA-CSIC), Valencia, Spain.
López-Almela I; Microbial Ecology, Nutrition and Health Research Unit, Institute of Agrochemistry and Food Technology, National Research Council (IATA-CSIC), Valencia, Spain.
Bullich-Vilarrubias C; Microbial Ecology, Nutrition and Health Research Unit, Institute of Agrochemistry and Food Technology, National Research Council (IATA-CSIC), Valencia, Spain.
Rueda-Ruzafa L; Laboratory of Neuroscience, Biomedical Research Center (CINBIO), University of Vigo, Vigo, Spain.
Gómez Del Pulgar EM; Microbial Ecology, Nutrition and Health Research Unit, Institute of Agrochemistry and Food Technology, National Research Council (IATA-CSIC), Valencia, Spain.
Benítez-Páez A; Microbial Ecology, Nutrition and Health Research Unit, Institute of Agrochemistry and Food Technology, National Research Council (IATA-CSIC), Valencia, Spain.
Liebisch G; Institute of Clinical Chemistry and Laboratory Medicine, University of Regensburg, Regensburg, Germany.
Lamas JA; Laboratory of Neuroscience, Biomedical Research Center (CINBIO), University of Vigo, Vigo, Spain.
Sanz Y; Microbial Ecology, Nutrition and Health Research Unit, Institute of Agrochemistry and Food Technology, National Research Council (IATA-CSIC), Valencia, Spain.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Jul; Vol. 35 (7), pp. e21734.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 2/*metabolism
Diabetes Mellitus, Type 2/*microbiology
Firmicutes/*physiology
Glucagon-Like Peptide 1/*metabolism
Mice, Obese/*metabolism
Mice, Obese/*microbiology
Animals ; Blood Glucose/metabolism ; Disease Models, Animal ; Gluconeogenesis/physiology ; Glucose/metabolism ; Glucose Tolerance Test/methods ; Hyperglycemia/metabolism ; Insulin/metabolism ; Mice ; Mice, Inbred C57BL ; Obesity/metabolism ; Obesity/microbiology
SCR Organism :
Holdemanella biformis
Czasopismo naukowe
Tytuł :
Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain.
Autorzy :
Zhang M; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China.
Wang J; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China.
Zhang K; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China.
Lu G; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China.
Liu Y; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China.
Ren K; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China.
Wang W; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China.
Xin D; Division of Experimental Hematology and Cancer Biology, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Xu L; Center for molecular medicine, Pediatric Research Institute, Children's Hospital of Fudan University, Shanghai, China.
Mao H; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China.
Xing J; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China.
Gao X; Shaanxi Key Laboratory of Brain Disorders, Xi'an Medical University, Xi'an, Shaanxi, China.
Jin W; Institute of Cancer Neuroscience, Medical Frontier Innovation Research Center, The First Hospital of Lanzhou University, Lanzhou, China.
Berry K; Division of Experimental Hematology and Cancer Biology, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Mikoshiba K; Faculty of Science, Toho University, Funabashi, Japan.; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.
Wu S; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China. .
Lu QR; Division of Experimental Hematology and Cancer Biology, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. .
Zhao X; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, Shaanxi, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 24; Vol. 12 (1), pp. 5091. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*metabolism
DNA/*metabolism
DNA-Binding Proteins/*metabolism
Mice, Neurologic Mutants/*metabolism
Proto-Oncogene Proteins/*metabolism
Remyelination/*physiology
5-Methylcytosine/analogs & derivatives ; Animals ; Cell Cycle ; Cell Differentiation ; DNA Methylation ; DNA-Binding Proteins/genetics ; Genome ; Mice ; Mice, Knockout ; Oligodendroglia/metabolism ; Organogenesis ; Proto-Oncogene Proteins/genetics
Czasopismo naukowe
Tytuł :
Cartilage Oligomeric Matrix Protein Induced Arthritis-A New Model for Rheumatoid Arthritis in the C57BL/6 Mouse.
Autorzy :
Zhao Y; Department of Endocrinology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Urbonaviciute V; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Xu B; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Cai W; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Sener Z; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Ge C; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Holmdahl R; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Feb 23; Vol. 12, pp. 631249. Date of Electronic Publication: 2021 Feb 23 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mice, Inbred C57BL*
Arthritis, Experimental/*immunology
Arthritis, Experimental/*physiopathology
Cartilage Oligomeric Matrix Protein/*administration & dosage
Animals ; Cartilage Oligomeric Matrix Protein/immunology ; Epitopes, T-Lymphocyte/immunology ; Genes, MHC Class II ; Injections, Intradermal ; Male ; Mice ; Peptides/administration & dosage ; Peptides/chemical synthesis
Czasopismo naukowe
Tytuł :
Collaborative Cross mice reveal extreme epilepsy phenotypes and genetic loci for seizure susceptibility.
Autorzy :
Gu B; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, USA.; Neuroscience Center, University of North Carolina, Chapel Hill, NC, USA.
Shorter JR; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Carolina Institute for Developmental Disabilities, University of North Carolina, Chapel Hill, NC, USA.; Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services, Copenhagen, Denmark.; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark.
Williams LH; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
Bell TA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Hock P; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Dalton KA; Neuroscience Curriculum, University of North Carolina, Chapel Hill, NC, USA.
Pan Y; Neuroscience Curriculum, University of North Carolina, Chapel Hill, NC, USA.
Miller DR; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Shaw GD; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Philpot BD; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, USA.; Neuroscience Center, University of North Carolina, Chapel Hill, NC, USA.; Carolina Institute for Developmental Disabilities, University of North Carolina, Chapel Hill, NC, USA.; Neuroscience Curriculum, University of North Carolina, Chapel Hill, NC, USA.
Pardo-Manuel de Villena F; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Carolina Institute for Developmental Disabilities, University of North Carolina, Chapel Hill, NC, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
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Źródło :
Epilepsia [Epilepsia] 2020 Sep; Vol. 61 (9), pp. 2010-2021. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mice*
Collaborative Cross Mice/*genetics
Epilepsy/*genetics
Hippocampus/*metabolism
Seizures/*genetics
Animals ; Chromosome Mapping ; Convulsants ; Epilepsy/chemically induced ; Epilepsy/metabolism ; Epilepsy/physiopathology ; Excitatory Amino Acid Agonists ; Flurothyl ; Gene Expression ; Gene Expression Profiling ; Genetic Predisposition to Disease ; Genotype ; Kainic Acid ; Mice, Inbred Strains ; Pentylenetetrazole ; Phenotype ; Quantitative Trait Loci ; Seizures/chemically induced ; Seizures/metabolism ; Seizures/physiopathology ; Sudden Unexpected Death in Epilepsy ; Whole Genome Sequencing
Czasopismo naukowe
Tytuł :
Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells.
Autorzy :
Song Y; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.; Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.
Shan L; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. .; Department of Medicine, Pathology and Immunology, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA.
Gbyli R; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.
Liu W; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.
Strowig T; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.; Helmholtz Centre for Infection Research, Braunschweig, Germany.
Patel A; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.
Fu X; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.; Department of Laboratory Medicine, Shenzhen Children's Hospital, Shenzhen, People's Republic of China.
Wang X; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.; Department of Hematology, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.
Xu ML; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
Gao Y; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.
Qin A; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.
Bruscia EM; Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA.
Tebaldi T; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy.
Biancon G; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.
Mamillapalli P; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.
Urbonas D; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Eynon E; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Gonzalez DG; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Chen J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Krause DS; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.; Department of Laboratory Medicine, Yale School of Medicine, New Haven, CT, USA.
Alderman J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Halene S; Section of Hematology, Department of Internal Medicine, Yale Cancer Center, and Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA. .; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.
Flavell RA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. .; Howard Hughes Medical Institute, Yale University, New Haven, CT, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2021 Mar 05; Vol. 371 (6533), pp. 1019-1025.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Circulation*
Disease Models, Animal*
Mice*
Anemia, Sickle Cell/*blood
Erythrocytes/*cytology
Erythropoiesis/*physiology
Animals ; Cytokines/metabolism ; Erythropoiesis/genetics ; Female ; Gene Deletion ; Hematopoietic Stem Cells/cytology ; Humans ; Hydrolases/genetics ; Liver/physiology ; Mice, Mutant Strains ; Middle Aged
Czasopismo naukowe
Tytuł :
A Genetically Engineered Mouse Model of Malignant Testicular Germ Cell Tumors.
Autorzy :
Lyndaker AM; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.; Division of Mathematics and Natural Sciences, Elmira College, Elmira, NY, USA.
Pierpont TM; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Loehr AR; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Weiss RS; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2195, pp. 147-165.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Disease Models, Animal*
Mice, Transgenic*
Neoplasms, Germ Cell and Embryonal/*etiology
Neoplasms, Germ Cell and Embryonal/*pathology
Testicular Neoplasms/*etiology
Testicular Neoplasms/*pathology
Alleles ; Animals ; Antineoplastic Agents/pharmacology ; Biomarkers, Tumor ; Breeding ; Cell Line, Tumor ; Genetic Engineering ; Genotype ; Humans ; Male ; Mice ; Neoplasms, Germ Cell and Embryonal/drug therapy ; Testicular Neoplasms/drug therapy ; Xenograft Model Antitumor Assays
SCR Disease Name :
Testicular Germ Cell Tumor
Czasopismo naukowe
Tytuł :
Genetically Engineered Mouse Model in Ewing Sarcoma.
Autorzy :
Tanaka M; Division of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
Nakamura T; Division of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2226, pp. 183-189.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mice, Transgenic*
Bone Neoplasms/*genetics
Bone Neoplasms/*pathology
Sarcoma, Ewing/*genetics
Sarcoma, Ewing/*pathology
Animals ; Biomarkers, Tumor ; Biopsy ; Cell Line, Tumor ; Humans ; Mice ; Oncogene Proteins, Fusion ; Proto-Oncogene Protein c-fli-1 ; RNA-Binding Protein EWS
Czasopismo naukowe
Tytuł :
B-SOiD, an open-source unsupervised algorithm for identification and fast prediction of behaviors.
Autorzy :
Hsu AI; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, USA.
Yttri EA; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, USA. .; Neuroscience Institute, Carnegie Mellon University, Pittsburgh, PA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 31; Vol. 12 (1), pp. 5188. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Algorithms*
Behavior*
Behavioral Sciences/*methods
Mice/*physiology
Animals ; Behavior, Animal ; Behavioral Sciences/instrumentation ; Biomechanical Phenomena ; Female ; Humans ; Machine Learning ; Male ; Mice, Inbred C57BL ; Software
Czasopismo naukowe
Tytuł :
Comparative Effects of 1/4-inch and 1/8-inch Corncob Bedding on Cage Ammonia Levels, Behavior, and Respiratory Pathology of Male C57BL/6 and 129S1/Svlm Mice.
Autorzy :
Cantara SI; Division of Animal Resources, Emory University, Atlanta, Georgia;, Email: .
Blas-Machado U; Athens Veterinary Diagnostic Laboratory and Department of Veterinary Pathology, University of Georgia, College of Veterinary Medicine, Athens, Georgia.
Zhao X; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Moore RH; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Schroeder JP; Emory Integrated Core Facilities, Rodent Behavioral Core, Emory University School of Medicine, Atlanta, Georgia.
Lee VK; Division of Animal Resources, Emory University, Atlanta, Georgia; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia.
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Źródło :
Journal of the American Association for Laboratory Animal Science : JAALAS [J Am Assoc Lab Anim Sci] 2020 Nov 01; Vol. 59 (6), pp. 695-702. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Housing, Animal*
Mice, 129 Strain*
Mice, Inbred C57BL*
Ammonia/*toxicity
Behavior, Animal/*drug effects
Animals ; Male ; Maze Learning ; Mice ; Nose/pathology ; Species Specificity ; Zea mays
Czasopismo naukowe
Tytuł :
Electronic cigarettes cause alteration in cardiac structure and function in diet-induced obese mice.
Autorzy :
Hasan KM; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.
Friedman TC; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.; David Geffen School of Medicine at University of California, Los Angeles, CA, United States of America.
Parveen M; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.
Espinoza-Derout J; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.
Bautista F; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.
Razipour MM; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.
Shao XM; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.; David Geffen School of Medicine at University of California, Los Angeles, CA, United States of America.
Jordan MC; David Geffen School of Medicine at University of California, Los Angeles, CA, United States of America.
Roos KP; David Geffen School of Medicine at University of California, Los Angeles, CA, United States of America.
Mahata SK; VA San Diego Health Care System and University of California, San Diego, CA, United States of America.
Sinha-Hikim AP; Division of Endocrinology, Metabolism and Molecular Medicine, Department of Internal Medicine, Charles R. Drew University, Los Angeles, CA, United States of America.; David Geffen School of Medicine at University of California, Los Angeles, CA, United States of America.
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Źródło :
PloS one [PLoS One] 2020 Oct 01; Vol. 15 (10), pp. e0239671. Date of Electronic Publication: 2020 Oct 01 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Electronic Nicotine Delivery Systems*
Mice, Obese*
Diet, High-Fat/*adverse effects
Heart/*drug effects
Myocardium/*pathology
Smoking/*adverse effects
Animals ; Cotinine/blood ; Echocardiography ; Fatty Acids, Nonesterified/blood ; Heart/physiopathology ; Heart Ventricles/drug effects ; Heart Ventricles/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Microscopy, Electron, Transmission ; Myocardium/ultrastructure ; Nicotine/adverse effects ; Nicotine/blood ; Oxidative Stress/drug effects ; Ventricular Dysfunction, Left/chemically induced
Czasopismo naukowe
Tytuł :
An Ethanolic Extract of Artemisia dracunculus L. Enhances the Metabolic Benefits of Exercise in Diet-induced Obese Mice.
Autorzy :
Allerton TD; Pennington Biomedical Research Center, Baton Rouge LA.
Kowalski GM; Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, AUSTRALIA.
Stampley J; Department of Kinesiology, Louisiana State University, Baton Rouge, LA.
Irving BA; Department of Kinesiology, Louisiana State University, Baton Rouge, LA.
Lighton JRB; Sable Systems International, North Las Vegas, NV.
Floyd ZE; Pennington Biomedical Research Center, Baton Rouge LA.
Stephens JM; Pennington Biomedical Research Center, Baton Rouge LA.
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Źródło :
Medicine and science in sports and exercise [Med Sci Sports Exerc] 2021 Apr 01; Vol. 53 (4), pp. 712-723.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Lipid Metabolism*
Artemisia/*chemistry
Glucose/*metabolism
Mice, Obese/*metabolism
Physical Conditioning, Animal/*physiology
Plant Extracts/*pharmacology
Animals ; Body Composition ; Diet, High-Fat ; Drinking Behavior ; Energy Metabolism/physiology ; Gene Expression ; Glucose Tolerance Test/methods ; Glycogen/metabolism ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Muscle, Skeletal/metabolism ; Obesity/etiology ; Oxidation-Reduction ; Random Allocation ; Triglycerides/blood
Czasopismo naukowe
Tytuł :
HLA transgenic mice: application in reproducing idiosyncratic drug toxicity.
Autorzy :
Susukida T; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.; Laboratory of Cancer Biology and Immunology, Section of Host Defenses, Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Aoki S; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Shirayanagi T; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Yamada Y; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Kuwahara S; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Ito K; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
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Źródło :
Drug metabolism reviews [Drug Metab Rev] 2020 Nov; Vol. 52 (4), pp. 540-567. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Disease Models, Animal*
Mice, Transgenic*
Antiviral Agents/*toxicity
HLA Antigens/*genetics
Virus Diseases/*drug therapy
Alleles ; Animals ; Antiviral Agents/therapeutic use ; Dideoxynucleosides/therapeutic use ; Dideoxynucleosides/toxicity ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Mice
Czasopismo naukowe
Tytuł :
Spatiotemporal contribution of neuromesodermal progenitor-derived neural cells in the elongation of developing mouse spinal cord.
Autorzy :
Shaker MR; Department of Anatomy and Division of Brain, Korea 21 Plus Program for Biomedical Science, Korea University College of Medicine, 73, Inchon-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Lee JH; Department of Anatomy and Division of Brain, Korea 21 Plus Program for Biomedical Science, Korea University College of Medicine, 73, Inchon-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Kim KH; Division of Pediatric Neurosurgery, Pediatric Clinical Neuroscience Center, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehakro, Jongno-gu, Seoul 110-769, Republic of Korea; Neural Development and Anomaly Laboratory, Department of Anatomy and Cell Biology, Seoul National University College of Medicine, 101 Daehakro, Jongno-gu, Seoul, 110-769, Republic of Korea.
Ban S; Neural Development and Anomaly Laboratory, Department of Anatomy and Cell Biology, Seoul National University College of Medicine, 101 Daehakro, Jongno-gu, Seoul, 110-769, Republic of Korea.
Kim VJ; Neural Development and Anomaly Laboratory, Department of Anatomy and Cell Biology, Seoul National University College of Medicine, 101 Daehakro, Jongno-gu, Seoul, 110-769, Republic of Korea.
Kim JY; Department of Anatomy and Division of Brain, Korea 21 Plus Program for Biomedical Science, Korea University College of Medicine, 73, Inchon-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Lee JY; Division of Pediatric Neurosurgery, Pediatric Clinical Neuroscience Center, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehakro, Jongno-gu, Seoul 110-769, Republic of Korea; Neural Development and Anomaly Laboratory, Department of Anatomy and Cell Biology, Seoul National University College of Medicine, 101 Daehakro, Jongno-gu, Seoul, 110-769, Republic of Korea.
Sun W; Department of Anatomy and Division of Brain, Korea 21 Plus Program for Biomedical Science, Korea University College of Medicine, 73, Inchon-ro, Seongbuk-gu, Seoul 02841, Republic of Korea. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Oct 01; Vol. 282, pp. 119393. Date of Electronic Publication: 2021 May 15.
Typ publikacji :
Journal Article
MeSH Terms :
Mesoderm/*embryology
Mice/*embryology
Neural Stem Cells/*cytology
Spinal Cord/*embryology
Animals ; Embryo, Mammalian/embryology ; Female ; Mice, Inbred C57BL
Czasopismo naukowe

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