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Wyszukujesz frazę ""SARS-CoV-2"" wg kryterium: Temat


Tytuł :
SARS-CoV-2 Virus-Host Interaction: Currently Available Structures and Implications of Variant Emergence on Infectivity and Immune Response.
Autorzy :
Queirós-Reis L; Abel Salazar Institute of Biomedical Sciences (ICBAS), University of Porto, 4050-313 Porto, Portugal.
Gomes da Silva P; Abel Salazar Institute of Biomedical Sciences (ICBAS), University of Porto, 4050-313 Porto, Portugal.; Epidemiology Research Unit (EPIunit), Institute of Public Health, University of Porto, 4050-091 Porto, Portugal.; LEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal.
Gonçalves J; Institute of Sustainable Processes, University of Valladolid, 47011 Valladolid, Spain.
Brancale A; Cardiff School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF10 3NB, UK.
Bassetto M; Department of Chemistry, Faculty of Science and Engineering, Swansea University, Swansea SA2 8PP, UK.
Mesquita JR; Abel Salazar Institute of Biomedical Sciences (ICBAS), University of Porto, 4050-313 Porto, Portugal.; Epidemiology Research Unit (EPIunit), Institute of Public Health, University of Porto, 4050-091 Porto, Portugal.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 07; Vol. 22 (19). Date of Electronic Publication: 2021 Oct 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Host-Pathogen Interactions*
COVID-19/*immunology
SARS-CoV-2/*immunology
SARS-CoV-2/*physiology
Angiotensin-Converting Enzyme 2/chemistry ; Angiotensin-Converting Enzyme 2/immunology ; Animals ; COVID-19/virology ; Humans ; Immunity ; Models, Molecular ; Mutation ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
SARS-CoV-2 Infection: New Molecular, Phylogenetic, and Pathogenetic Insights. Efficacy of Current Vaccines and the Potential Risk of Variants.
Autorzy :
Rotondo JC; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.; Center for Studies on Gender Medicine, Department of Medical Sciences, University of Ferrara, 64/b, Fossato di Mortara Street, 44121 Ferrara, Italy.
Martini F; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.; Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, 44121 Ferrara, Italy.
Maritati M; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Mazziotta C; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.; Center for Studies on Gender Medicine, Department of Medical Sciences, University of Ferrara, 64/b, Fossato di Mortara Street, 44121 Ferrara, Italy.
Di Mauro G; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.; Center for Studies on Gender Medicine, Department of Medical Sciences, University of Ferrara, 64/b, Fossato di Mortara Street, 44121 Ferrara, Italy.
Lanzillotti C; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.; Center for Studies on Gender Medicine, Department of Medical Sciences, University of Ferrara, 64/b, Fossato di Mortara Street, 44121 Ferrara, Italy.
Barp N; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Gallerani A; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Tognon M; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
Contini C; Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.
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Źródło :
Viruses [Viruses] 2021 Aug 25; Vol. 13 (9). Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
COVID-19/*virology
SARS-CoV-2/*classification
SARS-CoV-2/*genetics
Animals ; COVID-19/immunology ; COVID-19/prevention & control ; COVID-19/transmission ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/immunology ; Cytokine Release Syndrome ; Disease Management ; Gene Expression Regulation, Viral ; Genome, Viral ; Genomics/methods ; Host-Pathogen Interactions/immunology ; Humans ; Phylogeny ; SARS-CoV-2/immunology ; SARS-CoV-2/pathogenicity ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology ; Structure-Activity Relationship ; Viral Proteins/chemistry ; Viral Proteins/genetics ; Viral Zoonoses
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Peptide Platform as a Powerful Tool in the Fight against COVID-19.
Autorzy :
Murdocca M; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Citro G; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Romeo I; Department of Health Science, University 'Magna Graecia' of Catanzaro, Campus 'S. Venuta', Viale Europa, 88100 Catanzaro, Italy.; Net4Science Academic Spin-Off, University 'Magna Graecia' of Catanzaro, Campus 'S. Venuta', Viale Europa, 88100 Catanzaro, Italy.
Lupia A; Net4Science Academic Spin-Off, University 'Magna Graecia' of Catanzaro, Campus 'S. Venuta', Viale Europa, 88100 Catanzaro, Italy.
Miersch S; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada.
Amadio B; SAFU-IRE, Regina Elena Cancer Institute, 00128 Rome, Italy.
Bonomo A; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Rossi A; Institute of Translational Pharmacology, CNR, 00133 Rome, Italy.
Sidhu SS; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada.
Pandolfi PP; Renown Institute for Cancer, Nevada System of Higher Education, Reno, NV 89502, USA.
Alcaro S; Department of Health Science, University 'Magna Graecia' of Catanzaro, Campus 'S. Venuta', Viale Europa, 88100 Catanzaro, Italy.; Net4Science Academic Spin-Off, University 'Magna Graecia' of Catanzaro, Campus 'S. Venuta', Viale Europa, 88100 Catanzaro, Italy.
Sangiuolo FC; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Novelli G; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.; IRCCS Neuromed, 86077 Pozzilli (IS), Italy.; Department of Pharmacology, School of Medicine, University of Nevada, Reno, NV 89557, USA.
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Źródło :
Viruses [Viruses] 2021 Aug 23; Vol. 13 (8). Date of Electronic Publication: 2021 Aug 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dipeptidyl Peptidase 4/*chemistry
Peptide Fragments/*immunology
Peptide Fragments/*pharmacology
SARS-CoV-2/*drug effects
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Angiotensin-Converting Enzyme 2/chemistry ; Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Broadly Neutralizing Antibodies/immunology ; COVID-19/drug therapy ; COVID-19/prevention & control ; COVID-19 Vaccines/immunology ; Chlorocebus aethiops ; Dipeptidyl Peptidase 4/metabolism ; Epitopes, T-Lymphocyte/immunology ; Humans ; Mice ; Mice, Inbred BALB C ; Models, Molecular ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Peptide Fragments/chemistry ; Peptide Fragments/metabolism ; Protein Binding ; Protein Domains ; Receptors, Coronavirus/chemistry ; Receptors, Coronavirus/metabolism ; SARS-CoV-2/chemistry ; SARS-CoV-2/physiology ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/metabolism ; Vero Cells ; Virus Internalization
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
The mutation that helps Delta spread like wildfire.
Autorzy :
Callaway E
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Źródło :
Nature [Nature] 2021 Aug; Vol. 596 (7873), pp. 472-473.
Typ publikacji :
Wiadomości
MeSH Terms :
Amino Acid Substitution*
Mutation*
COVID-19/*transmission
COVID-19/*virology
SARS-CoV-2/*genetics
SARS-CoV-2/*pathogenicity
Spike Glycoprotein, Coronavirus/*genetics
COVID-19/epidemiology ; Cells, Cultured ; Furin/metabolism ; Humans ; SARS-CoV-2/growth & development ; SARS-CoV-2/isolation & purification ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/metabolism
SCR Organism :
SARS-CoV-2 variants
Periodyk
Tytuł :
Efficacy and safety of ReDuNing injection as a treatment for COVID-19 and its inhibitory effect against SARS-CoV-2.
Autorzy :
Ma Q; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, postcode, PR China.
Xie Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, postcode, PR China.
Wang Z; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, postcode, PR China.
Lei B; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, postcode, PR China.
Chen R; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, postcode, PR China.
Liu B; Kunming University of Science and Technology Library, Kunming, China.
Jiang H; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, postcode, PR China.
Wang Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, postcode, PR China.
Liu Q; Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Institute of Traditional Chinese Medicine, Beijing, 100010, PR China. Electronic address: .
Yang Z; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, postcode, PR China; State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2021 Oct 28; Vol. 279, pp. 114367. Date of Electronic Publication: 2021 Jun 24.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/drug therapy
COVID-19*/epidemiology
COVID-19*/immunology
Drugs, Chinese Herbal*/administration & dosage
Drugs, Chinese Herbal*/adverse effects
SARS-CoV-2*/drug effects
SARS-CoV-2*/isolation & purification
Cytokines/*analysis
Antiviral Agents/administration & dosage ; Antiviral Agents/adverse effects ; COVID-19 Nucleic Acid Testing/methods ; Cell Line ; China/epidemiology ; Cytotoxicity Tests, Immunologic/methods ; Drug Monitoring/methods ; Female ; Hospitalization/statistics & numerical data ; Humans ; Male ; Middle Aged ; Symptom Assessment/methods ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Mutation-induced changes in the receptor-binding interface of the SARS-CoV-2 Delta variant B.1.617.2 and implications for immune evasion.
Autorzy :
Baral P; Department of Physics, Florida International University, Miami, FL, 33199, USA.
Bhattarai N; Department of Physics, Florida International University, Miami, FL, 33199, USA.
Hossen ML; Department of Physics, Florida International University, Miami, FL, 33199, USA.
Stebliankin V; Bioinformatics Research Group (BioRG), Knight Foundation School of Computing and Information Sciences, Florida International University, Miami, FL, 33199, USA.
Gerstman BS; Department of Physics, Florida International University, Miami, FL, 33199, USA; Biomolecular Sciences Institute, Florida International University, Miami, FL, 33199, USA.
Narasimhan G; Bioinformatics Research Group (BioRG), Knight Foundation School of Computing and Information Sciences, Florida International University, Miami, FL, 33199, USA; Biomolecular Sciences Institute, Florida International University, Miami, FL, 33199, USA.
Chapagain PP; Department of Physics, Florida International University, Miami, FL, 33199, USA; Biomolecular Sciences Institute, Florida International University, Miami, FL, 33199, USA. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Oct 15; Vol. 574, pp. 14-19. Date of Electronic Publication: 2021 Aug 15.
Typ publikacji :
Journal Article
MeSH Terms :
Angiotensin-Converting Enzyme 2/*immunology
COVID-19/*immunology
Immune Evasion/*immunology
Mutation/*immunology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Amino Acids/genetics ; Amino Acids/immunology ; Amino Acids/metabolism ; Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Antibodies, Viral/immunology ; Binding Sites/genetics ; Binding Sites/immunology ; COVID-19/metabolism ; COVID-19/virology ; Humans ; Immune Evasion/genetics ; Molecular Dynamics Simulation ; Mutation/genetics ; Neutralization Tests ; Protein Binding ; Protein Domains ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Origin, phylogeny, variability and epitope conservation of SARS-CoV-2 worldwide.
Autorzy :
Vale FF; Pathogen Genome Bioinformatics and Computational Biology, Research Institute for Medicines (iMed-ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisboa 1649-003, Portugal. Electronic address: .
Vítor JMB; Pathogen Genome Bioinformatics and Computational Biology, Research Institute for Medicines (iMed-ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisboa 1649-003, Portugal; Pharmacy, Pharmacology and Health Technologies Department, Faculty of Pharmacy, Universidade de Lisboa, Lisbon 1649-003, Portugal.
Marques AT; Pathogen Genome Bioinformatics and Computational Biology, Research Institute for Medicines (iMed-ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisboa 1649-003, Portugal.
Azevedo-Pereira JM; Host-Pathogen Interactions Unit, Research Institute for Medicines (iMed-ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisboa 1649-003, Portugal.
Anes E; Host-Pathogen Interactions Unit, Research Institute for Medicines (iMed-ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisboa 1649-003, Portugal.
Goncalves J; Molecular Microbiology and Biotechnology Department, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, Lisbon 1649-003, Portugal.
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Źródło :
Virus research [Virus Res] 2021 Oct 15; Vol. 304, pp. 198526. Date of Electronic Publication: 2021 Jul 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Pandemics*
SARS-CoV-2*/classification
SARS-CoV-2*/genetics
COVID-19/*virology
Animals ; COVID-19/epidemiology ; Databases, Genetic ; Genome, Viral ; Humans ; Mutation ; Phylogeography
Czasopismo naukowe
Tytuł :
dsmCRISPR: Dual synthetic mismatches CRISPR/Cas12a-based detection of SARS-CoV-2 D614G mutation.
Autorzy :
Huang X; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Zhang F; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Zhu K; Beijing Origingene-tech biotechnology Co., Ltd., Beijing, China.
Lin W; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Ma W; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China. Electronic address: .
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Źródło :
Virus research [Virus Res] 2021 Oct 15; Vol. 304, pp. 198530. Date of Electronic Publication: 2021 Aug 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/diagnosis
COVID-19*/virology
Pandemics*
SARS-CoV-2*/genetics
SARS-CoV-2*/isolation & purification
Spike Glycoprotein, Coronavirus/*genetics
CRISPR-Cas Systems ; Humans ; Mutation
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Natural and Recombinant SARS-CoV-2 Isolates Rapidly Evolve In Vitro to Higher Infectivity through More Efficient Binding to Heparan Sulfate and Reduced S1/S2 Cleavage.
Autorzy :
Shiliaev N; Department of Microbiology, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
Lukash T; Department of Microbiology, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
Palchevska O; Department of Microbiology, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
Crossman DK; UAB Genomics Core Facility, Department of Genetics, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
Green TJ; Department of Microbiology, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
Crowley MR; UAB Genomics Core Facility, Department of Genetics, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
Frolova EI; Department of Microbiology, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
Frolov I; Department of Microbiology, University of Alabama at Birminghamgrid.265892.2, Birmingham, Alabama, USA.
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Źródło :
Journal of virology [J Virol] 2021 Oct 13; Vol. 95 (21), pp. e0135721. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Evolution, Molecular*
Heparitin Sulfate/*metabolism
SARS-CoV-2/*pathogenicity
Spike Glycoprotein, Coronavirus/*metabolism
Adaptation, Biological ; Animals ; Binding Sites ; Chlorocebus aethiops ; Cytopathogenic Effect, Viral ; DNA, Complementary ; Furin/metabolism ; Heparin/metabolism ; Host-Pathogen Interactions ; Protein Binding ; Protein Domains ; Protein Processing, Post-Translational ; SARS-CoV-2/genetics ; SARS-CoV-2/metabolism ; Serial Passage ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Vero Cells ; Viral Plaque Assay ; Virus Attachment
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses.
Autorzy :
Ye C; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227; .; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Chiem K; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227.; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Park JG; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227.; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Silvas JA; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227.; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Morales Vasquez D; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227.; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Sourimant J; Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Lin MJ; Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA 98195.
Greninger AL; Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA 98195.
Plemper RK; Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Torrelles JB; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227.; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Kobie JJ; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL 35294.
Walter MR; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294.
de la Torre JC; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
Martinez-Sobrido L; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227; .; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Oct 12; Vol. 118 (41).
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/genetics
COVID-19*/metabolism
Gene Expression Regulation, Viral*
Genes, Reporter*
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
Viral Proteins*/biosynthesis
Viral Proteins*/genetics
Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Chlorocebus aethiops ; Coronavirus Nucleocapsid Proteins/biosynthesis ; Coronavirus Nucleocapsid Proteins/genetics ; Female ; Humans ; Mice ; Mice, Transgenic ; Teschovirus/genetics ; Vero Cells
Czasopismo naukowe
Tytuł :
SARS-CoV-2 genomic surveillance in Northeast Brazil: timing of emergence of the Brazilian variant of concern P1.
Autorzy :
Dos Santos CA; Health Foundation Parreiras Horta, Central Laboratory of Public Health (LACEN/SE), Sergipe State Health Secretariat, Aracaju, Sergipe, Brazil.
Bezerra GVB; Health Foundation Parreiras Horta, Central Laboratory of Public Health (LACEN/SE), Sergipe State Health Secretariat, Aracaju, Sergipe, Brazil.
de Azevedo Marinho ARRA; Health Foundation Parreiras Horta, Central Laboratory of Public Health (LACEN/SE), Sergipe State Health Secretariat, Aracaju, Sergipe, Brazil.
Alves JC; Health Foundation Parreiras Horta, Central Laboratory of Public Health (LACEN/SE), Sergipe State Health Secretariat, Aracaju, Sergipe, Brazil.
Tanajura DM; Investigative Pathology Laboratory, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Martins-Filho PR; Investigative Pathology Laboratory, Federal University of Sergipe, Aracaju, Sergipe, Brazil.; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
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Źródło :
Journal of travel medicine [J Travel Med] 2021 Oct 11; Vol. 28 (7).
Typ publikacji :
Letter
MeSH Terms :
COVID-19*
SARS-CoV-2*
Brazil ; Genomics ; Humans ; Mutation
Opinia redakcyjna
Tytuł :
Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition.
Autorzy :
Kramer KJ; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Johnson NV; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.
Shiakolas AR; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Suryadevara N; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Periasamy S; Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA; Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.
Raju N; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Williams JK; Integral Molecular, Philadelphia, PA 19104, USA.
Wrapp D; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.
Zost SJ; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Walker LM; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Wall SC; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Holt CM; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Program in Chemical and Physical Biology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Hsieh CL; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.
Sutton RE; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Paulo A; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Nargi RS; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Davidson E; Integral Molecular, Philadelphia, PA 19104, USA.
Doranz BJ; Integral Molecular, Philadelphia, PA 19104, USA.
Crowe JE Jr; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Bukreyev A; Department of Pathology, University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA; Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX 77555, USA.
Carnahan RH; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
McLellan JS; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA. Electronic address: .
Georgiev IS; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Electrical Engineering and Computer Science, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA; Program in Computational Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2021 Oct 05; Vol. 37 (1), pp. 109784. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiotensin-Converting Enzyme 2/*immunology
Antibodies, Monoclonal/*immunology
Antibodies, Neutralizing/*immunology
COVID-19/*immunology
SARS-CoV-2/*chemistry
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Angiotensin-Converting Enzyme 2/chemistry ; Animals ; Antibodies, Viral/immunology ; Antibody Formation ; COVID-19/genetics ; COVID-19/virology ; Cell Line ; Chlorocebus aethiops ; Cryoelectron Microscopy ; Epitope Mapping/methods ; Epitopes/chemistry ; Epitopes/immunology ; High-Throughput Screening Assays/methods ; Humans ; Male ; Middle Aged ; Protein Binding ; Protein Interaction Domains and Motifs ; Receptors, Antigen, B-Cell/chemistry ; Receptors, Antigen, B-Cell/immunology ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/chemistry ; Vero Cells
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Structural modelling of SARS-CoV-2 alpha variant (B.1.1.7) suggests enhanced furin binding and infectivity.
Autorzy :
Mohammad A; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Kuwait.
Abubaker J; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Kuwait.
Al-Mulla F; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Kuwait.
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Źródło :
Virus research [Virus Res] 2021 Oct 02; Vol. 303, pp. 198522. Date of Electronic Publication: 2021 Jul 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Furin/*metabolism
SARS-CoV-2/*physiology
Spike Glycoprotein, Coronavirus/*metabolism
Binding Sites ; Furin/chemistry ; Models, Molecular ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Mutation ; Protein Binding ; Protein Conformation ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Induction of Exaggerated Cytokine Production in Human Peripheral Blood Mononuclear Cells by a Recombinant SARS-CoV-2 Spike Glycoprotein S1 and Its Inhibition by Dexamethasone.
Autorzy :
Olajide OA; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK. .
Iwuanyanwu VU; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK.
Lepiarz-Raba I; BRAINCITY-EMBL-Nencki Center of Excellence for Neuronal Plasticity and Brain Disorders, Nencki Institute of Experimental Biology, Warsaw, Poland.
Al-Hindawi AA; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield, HD1 3DH, UK.
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Źródło :
Inflammation [Inflammation] 2021 Oct; Vol. 44 (5), pp. 1865-1877. Date of Electronic Publication: 2021 Apr 16.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Cytokine Release Syndrome/*virology
Cytokines/*metabolism
Dexamethasone/*pharmacology
Leukocytes, Mononuclear/*metabolism
SARS-CoV-2/*pathogenicity
Spike Glycoprotein, Coronavirus/*immunology
Anti-Inflammatory Agents/therapeutic use ; Biomarkers/metabolism ; Blotting, Western ; COVID-19/drug therapy ; COVID-19/immunology ; COVID-19/virology ; Cells, Cultured ; Cytokine Release Syndrome/drug therapy ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/metabolism ; Dexamethasone/therapeutic use ; Enzyme-Linked Immunosorbent Assay ; Humans ; Leukocytes, Mononuclear/drug effects ; Recombinant Proteins/immunology ; SARS-CoV-2/immunology
Czasopismo naukowe
Tytuł :
Effect of dihydromyricetin on SARS-CoV-2 viral replication and pulmonary inflammation and fibrosis.
Autorzy :
Xiao T; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China; Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China.
Wei Y; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China; Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China.
Cui M; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China; Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China.
Li X; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China; Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China.
Ruan H; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China.
Zhang L; Department of Thoracic Surgery, Tianjin First Central Hospital, Nankai University, 300192 Tianjin, People's Republic of China.
Bao J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China; Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China.
Ren S; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China; Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China.
Gao D; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China; Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China.
Wang M; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China.
Sun R; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China; Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China.
Li M; Department of Thoracic Surgery, Tianjin First Central Hospital, Nankai University, 300192 Tianjin, People's Republic of China.
Lin J; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China.
Li D; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China. Electronic address: .
Yang C; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China; Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China. Electronic address: .
Zhou H; State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Haihe Education Park, 38 Tongyan Road, Tianjin 300353, People's Republic of China; Tianjin Key Laboratory of Molecular Drug Research, Tianjin International Joint Academy of Biomedicine, Tianjin, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Oct; Vol. 91, pp. 153704. Date of Electronic Publication: 2021 Aug 08.
Typ publikacji :
Journal Article
MeSH Terms :
Protease Inhibitors*/pharmacology
SARS-CoV-2*/drug effects
SARS-CoV-2*/physiology
Virus Replication*/drug effects
Coronavirus 3C Proteases/*antagonists & inhibitors
Flavonols/*pharmacology
Animals ; Antiviral Agents/pharmacology ; COVID-19 ; Fibrosis ; Humans ; Lung/pathology ; Lung/virology ; Mice ; Mice, Inbred C57BL ; Molecular Docking Simulation
Czasopismo naukowe
Tytuł :
Performance of 30 commercial SARS-CoV-2 serology assays in testing symptomatic COVID-19 patients.
Autorzy :
Vauloup-Fellous C; AP-HP, Hôpital Paul-Brousse, Virologie, Department of Virology, University Paris Saclay, INSERM U1193, 94804, Villejuif, France. .
Maylin S; Département des Agents Infectieux, Service de Virologie, Hôpital Saint-Louis, Université de Paris, INSERM UMR 944, Paris, France.
Périllaud-Dubois C; AP-HP, Hôpital Paul-Brousse, Virologie, Department of Virology, University Paris Saclay, INSERM U1193, 94804, Villejuif, France.
Brichler S; Laboratoire de Microbiologie Clinique, Centre national de référence des hépatites B, C et Delta, Hôpital Avicenne, Université Paris Nord, 93009, Bobigny, France.; Unité INSERM U955, Créteil, France.
Alloui C; Laboratoire de Microbiologie Clinique, Centre national de référence des hépatites B, C et Delta, Hôpital Avicenne, Université Paris Nord, 93009, Bobigny, France.; Unité INSERM U955, Créteil, France.
Gordien E; Laboratoire de Microbiologie Clinique, Centre national de référence des hépatites B, C et Delta, Hôpital Avicenne, Université Paris Nord, 93009, Bobigny, France.; Unité INSERM U955, Créteil, France.
Rameix-Welti MA; Laboratoire de Microbiologie, AP-HP. Université Paris Saclay, Hôpital Ambroise Paré, Boulogne-Billancourt, France.; INSERM, Université Paris-Saclay, Université de Versailles St. Quentin, UMR 1173 (2I), Versailles, France.
Gault E; Laboratoire de Microbiologie, AP-HP. Université Paris Saclay, Hôpital Ambroise Paré, Boulogne-Billancourt, France.; INSERM, Université Paris-Saclay, Université de Versailles St. Quentin, UMR 1173 (2I), Versailles, France.
Moreau F; Laboratoire de Microbiologie, AP-HP. Université Paris Saclay, Hôpital Ambroise Paré, Boulogne-Billancourt, France.; INSERM, Université Paris-Saclay, Université de Versailles St. Quentin, UMR 1173 (2I), Versailles, France.
Fourati S; Department of Virology, Hôpital Henri Mondor, 'Viruses, Hepatology, Cancer' Research Unit, Université Paris-Est, INSERM U955, Créteil, France.
Challine D; Department of Virology, Hôpital Henri Mondor, 'Viruses, Hepatology, Cancer' Research Unit, Université Paris-Est, INSERM U955, Créteil, France.
Pawlotsky JM; Department of Virology, Hôpital Henri Mondor, 'Viruses, Hepatology, Cancer' Research Unit, Université Paris-Est, INSERM U955, Créteil, France.
Houhou-Fidouh N; Laboratoire de Virologie, AP-HP, Hôpital Bichat-Claude Bernard, Université de Paris, INSERM UMR 1137 IAME, F-75018, Paris, France.
Damond F; Laboratoire de Virologie, AP-HP, Hôpital Bichat-Claude Bernard, Université de Paris, INSERM UMR 1137 IAME, F-75018, Paris, France.
Mackiewicz V; Laboratoire de Virologie, AP-HP, Hôpital Bichat-Claude Bernard, Université de Paris, INSERM UMR 1137 IAME, F-75018, Paris, France.
Charpentier C; Laboratoire de Virologie, AP-HP, Hôpital Bichat-Claude Bernard, Université de Paris, INSERM UMR 1137 IAME, F-75018, Paris, France.
Méritet JF; Service de Virologie, Hôpital Cochin - APHP Centre - Université de Paris, Paris, France.
Rozenberg F; Service de Virologie, Hôpital Cochin - APHP Centre - Université de Paris, Paris, France.
Podglajen I; Service de Virologie, Hôpital Européen Georges Pompidou-APHP Centre - Université de Paris, Paris, France.
Marot S; Institut Pierre Louis d'Epidémiologie et de Santé Publique, IPLESP, AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire de virologie, Sorbonne Université, INSERM, Paris, France.
Petit H; Institut Pierre Louis d'Epidémiologie et de Santé Publique, IPLESP, AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire de virologie, Sorbonne Université, INSERM, Paris, France.
Burrel S; Institut Pierre Louis d'Epidémiologie et de Santé Publique, IPLESP, AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire de virologie, Sorbonne Université, INSERM, Paris, France.
Akhavan S; Institut Pierre Louis d'Epidémiologie et de Santé Publique, IPLESP, AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire de virologie, Sorbonne Université, INSERM, Paris, France.
Leruez-Ville M; APHP Laboratoire de Microbiologie clinique, Hôpital Necker, Université de Paris, Faculté de Médecine, INSERM U1016, CNRS UMR 8104, Institut Cochin, Paris, France.
Avettand-Fenoel V; APHP Laboratoire de Microbiologie clinique, Hôpital Necker, Université de Paris, Faculté de Médecine, INSERM U1016, CNRS UMR 8104, Institut Cochin, Paris, France.
Fourgeaud J; APHP Laboratoire de Microbiologie clinique, Hôpital Necker, Université de Paris, Faculté de Médecine, INSERM U1016, CNRS UMR 8104, Institut Cochin, Paris, France.
Guilleminot T; APHP Laboratoire de Microbiologie clinique, Hôpital Necker, Université de Paris, Faculté de Médecine, INSERM U1016, CNRS UMR 8104, Institut Cochin, Paris, France.
Gardiennet E; APHP Laboratoire de Microbiologie clinique, Hôpital Necker, Université de Paris, Faculté de Médecine, INSERM U1016, CNRS UMR 8104, Institut Cochin, Paris, France.
Bonacorsi S; Service de Microbiologie, Hôpital Robert-Debré, Université de Paris, Paris, France.
Carol A; Service de Microbiologie, Hôpital Robert-Debré, Université de Paris, Paris, France.
Carcelain G; Laboratoire d'immunologie, Hôpital Robert-Debré, Université de Paris, Paris, France.
Villemonteix J; Laboratoire d'immunologie, Hôpital Robert-Debré, Université de Paris, Paris, France.
Boukli N; Département de Virologie (Hôpital Saint-Antoine, Tenon, Trousseau), AP-HP Sorbonne Université, INSERM-Sorbonne Universités UPMC, Université Paris 06, UMR-S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Paris, France.
Gozlan J; Département de Virologie (Hôpital Saint-Antoine, Tenon, Trousseau), AP-HP Sorbonne Université, INSERM-Sorbonne Universités UPMC, Université Paris 06, UMR-S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Paris, France.
Morand-Joubert L; Département de Virologie (Hôpital Saint-Antoine, Tenon, Trousseau), AP-HP Sorbonne Université, INSERM-Sorbonne Universités UPMC, Université Paris 06, UMR-S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Paris, France.
Legoff J; Département des Agents Infectieux, Service de Virologie, Hôpital Saint-Louis, Université de Paris, INSERM UMR 944, Paris, France.
Delaugerre C; Département des Agents Infectieux, Service de Virologie, Hôpital Saint-Louis, Université de Paris, INSERM UMR 944, Paris, France.
Chaix ML; Département des Agents Infectieux, Service de Virologie, Hôpital Saint-Louis, Université de Paris, INSERM UMR 944, Paris, France.
Roque-Afonso AM; AP-HP, Hôpital Paul-Brousse, Virologie, Department of Virology, University Paris Saclay, INSERM U1193, 94804, Villejuif, France.
Dortet L; Service de Bactériologie-Hygiène, Hôpital Bicêtre, Inserm U 1184; LabEx LERMIT, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Naas T; Service de Bactériologie-Hygiène, Hôpital Bicêtre, Inserm U 1184; LabEx LERMIT, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Ronat JB; Service de Bactériologie-Hygiène, Hôpital Bicêtre, Inserm U 1184; LabEx LERMIT, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Lepape S; AP-HP, Hôpital Paul-Brousse, Virologie, Department of Virology, University Paris Saclay, INSERM U1193, 94804, Villejuif, France.
Marcelin AG; Institut Pierre Louis d'Epidémiologie et de Santé Publique, IPLESP, AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire de virologie, Sorbonne Université, INSERM, Paris, France.
Descamps D; Laboratoire de Virologie, AP-HP, Hôpital Bichat-Claude Bernard, Université de Paris, INSERM UMR 1137 IAME, F-75018, Paris, France.
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Źródło :
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology [Eur J Clin Microbiol Infect Dis] 2021 Oct; Vol. 40 (10), pp. 2235-2241. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Antibodies, Viral/*blood
COVID-19/*blood
COVID-19 Serological Testing/*methods
Immunoassay/*methods
SARS-CoV-2/*immunology
COVID-19/virology ; Humans ; Immunoassay/economics ; Immunoglobulin M/blood ; Reagent Kits, Diagnostic ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Sensitivity and Specificity
Czasopismo naukowe
Tytuł :
COVID-19: Structural Considerations for Virus Pathogenesis, Therapeutic Strategies and Vaccine Design in the Novel SARS-CoV-2 Variants Era.
Autorzy :
Volkan E; Faculty of Pharmacy, Cyprus International University, via Mersin 10, 99258, Nicosia, Northern Cyprus, Turkey. .; Biotechnology Research Center, Cyprus International University, via Mersin 10, 99258, Nicosia, Northern Cyprus, Turkey. .
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Źródło :
Molecular biotechnology [Mol Biotechnol] 2021 Oct; Vol. 63 (10), pp. 885-897. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*prevention & control
COVID-19/*therapy
COVID-19 Vaccines/*immunology
SARS-CoV-2/*immunology
SARS-CoV-2/*pathogenicity
Angiotensin-Converting Enzyme 2/chemistry ; Angiotensin-Converting Enzyme 2/metabolism ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/therapeutic use ; Antibodies, Viral/immunology ; Antibodies, Viral/therapeutic use ; COVID-19/immunology ; COVID-19/virology ; COVID-19 Vaccines/therapeutic use ; Drug Design ; Humans ; SARS-CoV-2/genetics ; Severity of Illness Index ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology ; Spike Glycoprotein, Coronavirus/metabolism
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
2-Deoxy-d-glucose exploits increased glucose metabolism in cancer and viral-infected cells: Relevance to its use in India against SARS-CoV-2.
Autorzy :
Mesri EA; Department of Microbiology and Immunology, Miami, Florida, USA.; Cell Biology, Sylvester Comprehensive Cancer Center, Miami, Florida, USA.
Lampidis TJ; Cell Biology, Sylvester Comprehensive Cancer Center, Miami, Florida, USA.; Department of Cell Biology, Miami, Florida, USA.
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Źródło :
IUBMB life [IUBMB Life] 2021 Oct; Vol. 73 (10), pp. 1198-1204. Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review
MeSH Terms :
COVID-19/*metabolism
Deoxyglucose/*pharmacology
Glucose/*metabolism
Neoplasms/*metabolism
SARS-CoV-2/*drug effects
COVID-19/virology ; Humans ; India ; SARS-CoV-2/isolation & purification ; SARS-CoV-2/pathogenicity
Czasopismo naukowe
Tytuł :
Molecular biology of the SARs-CoV-2 spike protein: A review of current knowledge.
Autorzy :
Zhu C; Translational Medicine Laboratory of Pancreatic Diseases, Department of Hepatobiliary Surgery, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
He G; Department of Ophthalmology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
Yin Q; Department of Ophthalmology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
Zeng L; Institute of Translational Medicine, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
Ye X; Department of Medical Laboratory Science, School of Medicine, Hunan Normal University, Changsha, China.
Shi Y; Institute of Translational Medicine, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
Xu W; Institute of Translational Medicine, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.
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Źródło :
Journal of medical virology [J Med Virol] 2021 Oct; Vol. 93 (10), pp. 5729-5741. Date of Electronic Publication: 2021 Jun 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
SARS-CoV-2/*physiology
Spike Glycoprotein, Coronavirus/*chemistry
Spike Glycoprotein, Coronavirus/*metabolism
COVID-19/virology ; Host Specificity ; Humans ; Mutation ; Protein Conformation ; Protein Subunits ; Receptors, Virus/genetics ; Receptors, Virus/metabolism ; SARS-CoV-2/classification ; SARS-CoV-2/pathogenicity ; Spike Glycoprotein, Coronavirus/genetics ; Virus Internalization
Czasopismo naukowe
Tytuł :
A one-step real-time RT-PCR assay for simultaneous typing of SARS-CoV-2 mutations associated with the E484K and N501Y spike protein amino-acid substitutions.
Autorzy :
Chaintoutis SC; Diagnostic Laboratory, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 11 Stavrou Voutyra str., 54627, Thessaloniki, Greece.
Chassalevris T; Diagnostic Laboratory, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 11 Stavrou Voutyra str., 54627, Thessaloniki, Greece.
Tsiolas G; Institute of Applied Biosciences, Centre of Research and Technology Hellas, Thermi, 57001, Thessaloniki, Greece.
Balaska S; Department of Microbiology, AHEPA University Hospital, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 1 Stilponos Kyriakidi str., 54636, Thessaloniki, Greece.
Vlatakis I; EnzyQuest PC, Science and Technology Park of Crete, 100 Nikolaou Plastira str., Vassilika Vouton, 70013, Heraklion, Greece.
Mouchtaropoulou E; Institute of Applied Biosciences, Centre of Research and Technology Hellas, Thermi, 57001, Thessaloniki, Greece.
Siarkou VI; Laboratory of Microbiology and Infectious Diseases, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, University Campus, 54134, Thessaloniki, Greece.
Tychala A; Department of Microbiology, AHEPA University Hospital, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 1 Stilponos Kyriakidi str., 54636, Thessaloniki, Greece.
Koutsioulis D; EnzyQuest PC, Science and Technology Park of Crete, 100 Nikolaou Plastira str., Vassilika Vouton, 70013, Heraklion, Greece.
Skoura L; Department of Microbiology, AHEPA University Hospital, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, 1 Stilponos Kyriakidi str., 54636, Thessaloniki, Greece.
Argiriou A; Institute of Applied Biosciences, Centre of Research and Technology Hellas, Thermi, 57001, Thessaloniki, Greece; Department of Food Science and Nutrition, University of the Aegean, 81400, Myrina, Lemnos, Greece.
Dovas CI; Diagnostic Laboratory, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 11 Stavrou Voutyra str., 54627, Thessaloniki, Greece. Electronic address: .
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Źródło :
Journal of virological methods [J Virol Methods] 2021 Oct; Vol. 296, pp. 114242. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation*
COVID-19/*virology
Real-Time Polymerase Chain Reaction/*methods
Reverse Transcriptase Polymerase Chain Reaction/*methods
SARS-CoV-2/*genetics
Spike Glycoprotein, Coronavirus/*genetics
Amino Acid Substitution ; COVID-19/diagnosis ; COVID-19 Testing ; Humans ; Microbiological Techniques ; SARS-CoV-2/classification ; SARS-CoV-2/isolation & purification
Czasopismo naukowe

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