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Tytuł :
Recombinant turkey coronavirus: are some S gene structures of gammacoronaviruses especially prone to exchange?
Autorzy :
Domanska-Blicharz K; Department of Poultry Diseases, National Veterinary Research Institute, 24-100 Puławy, Poland. Electronic address: .
Sajewicz-Krukowska J; Department of Poultry Diseases, National Veterinary Research Institute, 24-100 Puławy, Poland.
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Źródło :
Poultry science [Poult Sci] 2021 Apr; Vol. 100 (4), pp. 101018. Date of Electronic Publication: 2021 Jan 26.
Typ publikacji :
Journal Article
MeSH Terms :
Coronavirus, Turkey*/genetics
Gammacoronavirus*/genetics
Infectious bronchitis virus*/genetics
Spike Glycoprotein, Coronavirus/*genetics
Animals ; Chickens ; Coronavirus Infections/veterinary ; Coronavirus Infections/virology ; Genome, Viral ; Phylogeny ; Poultry Diseases/virology
Czasopismo naukowe
Tytuł :
Why are ACE2 binding coronavirus strains SARS-CoV/SARS-CoV-2 wild and NL63 mild?
Autorzy :
Rawat P; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India.
Jemimah S; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India.
Ponnuswamy PK; Department of Physics, Bharathidasan University, Tiruchirapalli, India.
Gromiha MM; Department of Biotechnology, Bhupat and Jyoti Mehta School of Biosciences, Indian Institute of Technology Madras, Chennai, India.
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Źródło :
Proteins [Proteins] 2021 Apr; Vol. 89 (4), pp. 389-398. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus NL63, Human*
SARS Virus*
SARS-CoV-2*
Angiotensin-Converting Enzyme 2/*metabolism
COVID-19/*virology
Spike Glycoprotein, Coronavirus/*chemistry
Antiviral Agents/pharmacology ; Coronavirus Infections/virology ; DNA Mutational Analysis ; Humans ; Hydrophobic and Hydrophilic Interactions ; Ligands ; Models, Statistical ; Mutation ; Protein Binding ; Protein Conformation ; Species Specificity ; Spike Glycoprotein, Coronavirus/genetics
Czasopismo naukowe
Tytuł :
Coronavirus Occurrence in the Household Influenza Vaccine Evaluation (HIVE) Cohort of Michigan Households: Reinfection Frequency and Serologic Responses to Seasonal and Severe Acute Respiratory Syndrome Coronaviruses.
Autorzy :
Petrie JG; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Bazzi LA; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
McDermott AB; National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Follmann D; National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Esposito D; Protein Expression Laboratory, National Cancer Institute RAS Initiative, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Hatcher C; National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Mateja A; Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
Narpala SR; National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
O'Connell SE; National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Martin ET; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
Monto AS; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2021 Jul 02; Vol. 224 (1), pp. 49-59.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Coronavirus*/classification
Coronavirus*/genetics
Coronavirus*/immunology
Family Characteristics*
Coronavirus Infections/*epidemiology
Influenza Vaccines/*immunology
Influenza, Human/*epidemiology
Influenza, Human/*prevention & control
Severe Acute Respiratory Syndrome/*epidemiology
Antibodies, Viral/blood ; Antibodies, Viral/immunology ; COVID-19/epidemiology ; COVID-19/virology ; Coinfection/epidemiology ; Coronavirus Infections/diagnosis ; Coronavirus Infections/immunology ; Coronavirus Infections/virology ; Cross Reactions/immunology ; Humans ; Influenza Vaccines/administration & dosage ; Influenza, Human/virology ; Kaplan-Meier Estimate ; Michigan/epidemiology ; Proportional Hazards Models ; Public Health Surveillance ; Reinfection/epidemiology ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Seasons ; Seroepidemiologic Studies ; Severe Acute Respiratory Syndrome/diagnosis ; Severe Acute Respiratory Syndrome/immunology ; Severe Acute Respiratory Syndrome/virology ; Viral Load
Czasopismo naukowe
Tytuł :
A potential antiviral activity of Esculentoside A against binding interactions of SARS-COV-2 spike protein and angiotensin converting enzyme 2 (ACE2).
Autorzy :
Zeng MS; Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, PR China.
Yu WD; Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, PR China.
Wang HX; Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, PR China.
Liu JY; Basic Medical College, Guangzhou University of Chinese Medicine, Guangzhou, PR China.
Xu PP; Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, PR China. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Jul 31; Vol. 183, pp. 2248-2261. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article
MeSH Terms :
Angiotensin-Converting Enzyme 2*/chemistry
Angiotensin-Converting Enzyme 2*/metabolism
Antiviral Agents*/chemistry
Antiviral Agents*/pharmacology
Molecular Docking Simulation*
Molecular Dynamics Simulation*
SARS-CoV-2*/chemistry
SARS-CoV-2*/physiology
Saponins*/chemistry
Saponins*/pharmacology
Spike Glycoprotein, Coronavirus*/chemistry
Spike Glycoprotein, Coronavirus*/metabolism
COVID-19/*drug therapy
Oleanolic Acid/*analogs & derivatives
Cell Line, Tumor ; Coronavirus OC43, Human/chemistry ; Coronavirus OC43, Human/metabolism ; Humans ; Oleanolic Acid/chemistry ; Oleanolic Acid/pharmacology
Czasopismo naukowe
Tytuł :
SARS-CoV-2-derived fusion inhibitor lipopeptides exhibit highly potent and broad-spectrum activity against divergent human coronaviruses.
Autorzy :
Zhu Y; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yu D; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hu Y; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wu T; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Chong H; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
He Y; NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. .
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Źródło :
Signal transduction and targeted therapy [Signal Transduct Target Ther] 2021 Aug 03; Vol. 6 (1), pp. 294. Date of Electronic Publication: 2021 Aug 03.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents*/chemistry
Antiviral Agents*/pharmacology
Lipopeptides*/chemistry
Lipopeptides*/pharmacology
Middle East Respiratory Syndrome Coronavirus*/chemistry
Middle East Respiratory Syndrome Coronavirus*/metabolism
SARS-CoV-2*/chemistry
SARS-CoV-2*/metabolism
COVID-19/*drug therapy
COVID-19/*metabolism
Coronavirus Infections/*drug therapy
Virus Internalization/*drug effects
Coronavirus Infections/metabolism ; Humans
SCR Protocol :
COVID-19 drug treatment
Raport
Tytuł :
Sustained Responses of Neutralizing Antibodies Against Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Recovered Patients and Their Therapeutic Applicability.
Autorzy :
Kim YS; Division of Infectious Diseases, Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Republic of Korea.
Aigerim A; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Park U; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Kim Y; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Center for Infectious Diseases Research, Korea National Institute of Health, Korea Center for Disease Control and Prevention, Cheongju-si, Republic of Korea.
Park H; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Republic of Korea.
Rhee JY; Division of Infectious Diseases, Department of Medicine, Dankook University College of Medicine, Cheonan, Republic of Korea.
Choi JP; Department of Internal Medicine, Seoul Medical Center, Seoul, Republic of Korea.
Park WB; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Park SW; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Kim Y; Center for Infectious Diseases, National Medical Center, Seoul, Republic of Korea.
Lim DG; Center for Chronic Diseases, Research Institute, National Medical Center, Seoul, Republic of Korea.
Choi JY; Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jeon YK; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.; Department of Pathology, Seoul National University College of Medicine, Seoul, South Korea.
Yang JS; Center for Infectious Diseases Research, Korea National Institute of Health, Korea Center for Disease Control and Prevention, Cheongju-si, Republic of Korea.
Lee JY; Center for Infectious Diseases Research, Korea National Institute of Health, Korea Center for Disease Control and Prevention, Cheongju-si, Republic of Korea.
Shin HS; Center for Infectious Diseases, National Medical Center, Seoul, Republic of Korea.
Cho NH; Department of Microbiology and Immunology, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Department of Biomedical Sciences, College of Medicine, Seoul National University, Seoul, Republic of Korea.; Institute of Endemic Disease, Seoul National University Medical Research Center and Bundang Hospital, Seoul, Republic of Korea.
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Źródło :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2021 Aug 02; Vol. 73 (3), pp. e550-e558.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Infections*/drug therapy
Middle East Respiratory Syndrome Coronavirus*
Animals ; Antibodies, Neutralizing ; Antibodies, Viral ; Humans ; Mice ; Republic of Korea ; Spike Glycoprotein, Coronavirus
Czasopismo naukowe
Tytuł :
Coronavirus HKU 1 infection with bronchiolitis, pericardial effusion and acute respiratory failure in obese adult female.
Autorzy :
Bianchi F; Respiratory Diseases Unit, Department of Medical Sciences, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
Bennett D; Respiratory Diseases Unit, Department of Medical Sciences, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
Alderighi L; Respiratory Diseases Unit, Department of Medical Sciences, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
Pieroni M; Respiratory Diseases Unit, Department of Medical Sciences, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
Refini RM; Respiratory Diseases Unit, Department of Medical Sciences, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
Fossi A; Respiratory Diseases Unit, Department of Medical Sciences, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
Bargagli E; Respiratory Diseases Unit, Department of Medical Sciences, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
Mazzei MA; Diagnostic Imaging Unit, Department of Radiological Sciences, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
Guazzi G; Emergency Diagnostic, Department of Emergency and Urgency and Transplants, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
Cusi MG; Microbiology and Virology Unit, Department of Innovation, Experimentation and Clinical Research, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
Sestini P; Respiratory Diseases Unit, Department of Medical Sciences, University Hospital of Siena (Azienda Ospedaliera Universitaria Senese, AOUS), Siena, Italy.
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Źródło :
The Journal of asthma : official journal of the Association for the Care of Asthma [J Asthma] 2021 Aug; Vol. 58 (8), pp. 1128-1131. Date of Electronic Publication: 2020 May 04.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Coronavirus*
Bronchiolitis/*etiology
Coronavirus Infections/*complications
Pericardial Effusion/*etiology
Respiratory Insufficiency/*etiology
Anti-Bacterial Agents/therapeutic use ; Bronchiolitis/therapy ; Bronchodilator Agents/therapeutic use ; Ceftriaxone/therapeutic use ; Coronavirus Infections/therapy ; Female ; Humans ; Methylprednisolone/therapeutic use ; Middle Aged ; Obesity, Morbid/therapy ; Oxygen/therapeutic use ; Pericardial Effusion/therapy ; Respiratory Insufficiency/therapy
Czasopismo naukowe
Tytuł :
Direct Comparison of N- Glycans and Their Isomers Derived from Spike Glycoprotein 1 of MERS-CoV, SARS-CoV-1, and SARS-CoV-2.
Autorzy :
Cho BG; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, United States.
Gautam S; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, United States.
Peng W; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, United States.
Huang Y; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, United States.
Goli M; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, United States.
Mechref Y; Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, United States.
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Źródło :
Journal of proteome research [J Proteome Res] 2021 Sep 03; Vol. 20 (9), pp. 4357-4365. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
COVID-19*
Middle East Respiratory Syndrome Coronavirus*
Glycoproteins ; Humans ; Pandemics ; Polysaccharides ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/genetics
Czasopismo naukowe
Tytuł :
Immunity against seasonal human coronavirus OC43 mitigates fatal deterioration of COVID-19.
Autorzy :
Yamaguchi T; Research Institute, Nozaki Tokushukai Hospital, Daito City, Osaka, Japan. Electronic address: .
Shinagawa T; Research Institute, Nozaki Tokushukai Hospital, Daito City, Osaka, Japan.
Kobata H; Nozaki Tokushukai Hospital, Daito City, Osaka, Japan.
Nakagawa H; Nozaki Tokushukai Hospital, Daito City, Osaka, Japan.
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Źródło :
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2021 Aug; Vol. 109, pp. 261-268. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*
Coronavirus OC43, Human*
Antibodies, Viral ; Cross Reactions ; Humans ; SARS-CoV-2 ; Seasons ; Spike Glycoprotein, Coronavirus
Czasopismo naukowe
Tytuł :
Climate and Human coronaviruses 229E and Human coronaviruses OC43 Infections: Respiratory Viral Infections Prevalence in Hospitalized Children in Cheonan, Korea.
Autorzy :
Kim JM; Department of Health Administration, College of Health Sciences, Dankook University, Cheonan 31116, Republic of Korea.
Jeon JS; Department of Biomedical Laboratory Science, College of Health Sciences, Dankook University, Cheonan 31116, Republic of Korea.
Kim JK; Department of Biomedical Laboratory Science, College of Health Sciences, Dankook University, Cheonan 31116, Republic of Korea.
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Źródło :
Journal of microbiology and biotechnology [J Microbiol Biotechnol] 2020 Oct 28; Vol. 30 (10), pp. 1495-1499.
Typ publikacji :
Journal Article
MeSH Terms :
Climate*
Coronavirus OC43, Human*/genetics
Coronavirus OC43, Human*/isolation & purification
Coronavirus OC43, Human*/metabolism
Coronavirus Infections/*epidemiology
Respiratory Tract Infections/*epidemiology
Respiratory Tract Infections/*virology
Child ; Child, Preschool ; Coronavirus/genetics ; Coronavirus 229E, Human/isolation & purification ; Coronavirus 229E, Human/metabolism ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Prevalence ; Real-Time Polymerase Chain Reaction ; Republic of Korea/epidemiology ; Retrospective Studies
Czasopismo naukowe
Tytuł :
A severe case of human coronavirus 229E pneumonia in an elderly man with diabetes mellitus: a case report.
Autorzy :
Sun W; Department of Pulmonary and Critical Care Medicine, Peking University First Hospital, Beijing, 100034, China.
Liao JP; Department of Pulmonary and Critical Care Medicine, Peking University First Hospital, Beijing, 100034, China. .
Yu KY; Department of Pulmonary and Critical Care Medicine, Peking University First Hospital, Beijing, 100034, China.
Qiu JX; Department of Radiology, Peking University First Hospital, Beijing, 100034, China.
Que CL; Department of Pulmonary and Critical Care Medicine, Peking University First Hospital, Beijing, 100034, China.
Wang GF; Department of Pulmonary and Critical Care Medicine, Peking University First Hospital, Beijing, 100034, China.
Ma J; Department of Pulmonary and Critical Care Medicine, Peking University First Hospital, Beijing, 100034, China.
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2021 Jun 04; Vol. 21 (1), pp. 524. Date of Electronic Publication: 2021 Jun 04.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Coronavirus 229E, Human*
Common Cold/*diagnosis
Coronavirus Infections/*diagnosis
Pneumonia, Viral/*diagnosis
Aged ; Anti-Bacterial Agents/therapeutic use ; Bronchoalveolar Lavage Fluid/virology ; Common Cold/complications ; Common Cold/virology ; Coronavirus Infections/complications ; Diabetes Mellitus ; Healthcare-Associated Pneumonia/complications ; Healthcare-Associated Pneumonia/drug therapy ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Pneumonia, Viral/drug therapy
Czasopismo naukowe
Tytuł :
Structural basis for broad coronavirus neutralization.
Autorzy :
Sauer MM; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Tortorici MA; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institut Pasteur, Unité de Virologie Structurale, Paris, France.
Park YJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Walls AC; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Homad L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Acton OJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Bowen JE; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Wang C; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
Xiong X; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Guangzhou Regenerative Medicine and Health - Guangdong Laboratory, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
de van der Schueren W; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Bluebird Bio, Seattle, WA, USA.
Quispe J; Department of Biochemistry, University of Washington, Seattle, WA, USA.
Hoffstrom BG; Antibody Technology Resource, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Bosch BJ; Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
McGuire AT; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. .; Department of Global Health, University of Washington, Seattle, WA, USA. .; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA. .
Veesler D; Department of Biochemistry, University of Washington, Seattle, WA, USA. .
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Źródło :
Nature structural & molecular biology [Nat Struct Mol Biol] 2021 Jun; Vol. 28 (6), pp. 478-486. Date of Electronic Publication: 2021 May 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Antibodies, Monoclonal*/immunology
Antibodies, Monoclonal*/metabolism
Antibodies, Neutralizing*/immunology
Antibodies, Neutralizing*/metabolism
Antibodies, Viral*/immunology
Antibodies, Viral*/metabolism
Spike Glycoprotein, Coronavirus*/immunology
Spike Glycoprotein, Coronavirus*/metabolism
Betacoronavirus/*immunology
Coronavirus Infections/*immunology
Animals ; Coronavirus Infections/prevention & control ; Cross Reactions ; Epitopes ; Female ; HEK293 Cells ; Humans ; Mice ; Protein Binding
Czasopismo naukowe
Tytuł :
Broad spectrum anti-coronavirus activity of a series of anti-malaria quinoline analogues.
Autorzy :
Persoons L; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium.
Vanderlinden E; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium. Electronic address: .
Vangeel L; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium.
Wang X; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium.
Do NDT; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium.
Foo SC; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium.
Leyssen P; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium.
Neyts J; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium.
Jochmans D; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium.
Schols D; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium.
De Jonghe S; KU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Herestraat 49, Leuven, Belgium.
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Źródło :
Antiviral research [Antiviral Res] 2021 Sep; Vol. 193, pp. 105127. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimalarials/*pharmacology
Antiviral Agents/*pharmacology
Coronavirus/*drug effects
Coronavirus Infections/*drug therapy
Quinolines/*pharmacology
Animals ; COVID-19/drug therapy ; Chlorocebus aethiops ; Chloroquine/pharmacology ; Coronavirus 229E, Human/drug effects ; Coronavirus OC43, Human/drug effects ; Humans ; Hydroxychloroquine/pharmacology ; SARS-CoV-2/drug effects ; Vero Cells ; Virus Internalization/drug effects ; Virus Replication/drug effects
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Coronavirus Pseudotypes for All Circulating Human Coronaviruses for Quantification of Cross-Neutralizing Antibody Responses.
Autorzy :
Sampson AT; Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.
Heeney J; Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.; DIOSynVax Ltd., Cambridge CB3 0ES, UK.
Cantoni D; Viral Pseudotype Unit, University of Kent, Chatham ME4 4TB, UK.
Ferrari M; Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.; DIOSynVax Ltd., Cambridge CB3 0ES, UK.
Sans MS; Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.
George C; Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.
Di Genova C; Viral Pseudotype Unit, University of Kent, Chatham ME4 4TB, UK.
Mayora Neto M; Viral Pseudotype Unit, University of Kent, Chatham ME4 4TB, UK.
Einhauser S; Institute for Medical Microbiology and Hygiene, University of Regensburg, 93053 Regensburg, Germany.
Asbach B; Institute for Medical Microbiology and Hygiene, University of Regensburg, 93053 Regensburg, Germany.
Wagner R; Institute for Medical Microbiology and Hygiene, University of Regensburg, 93053 Regensburg, Germany.; Institute for Clinical Microbiology and Hygiene, University Hospital, 93053 Regensburg, Germany.
Baxendale H; Royal Papworth Hospital NHS Foundation Trust, Cambridge CB2 0AY, UK.
Temperton N; Viral Pseudotype Unit, University of Kent, Chatham ME4 4TB, UK.
Carnell G; Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.
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Źródło :
Viruses [Viruses] 2021 Aug 10; Vol. 13 (8). Date of Electronic Publication: 2021 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Viral/*immunology
Broadly Neutralizing Antibodies/*immunology
COVID-19/*immunology
Coronavirus/*immunology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*immunology
Animals ; Antibodies, Viral/blood ; Broadly Neutralizing Antibodies/blood ; Cell Line ; Coronavirus 229E, Human/immunology ; Coronavirus 229E, Human/physiology ; Coronavirus NL63, Human/immunology ; Coronavirus NL63, Human/physiology ; Coronavirus OC43, Human/immunology ; Coronavirus OC43, Human/physiology ; Cross Reactions ; Humans ; Lentivirus/genetics ; Middle East Respiratory Syndrome Coronavirus/immunology ; Middle East Respiratory Syndrome Coronavirus/physiology ; Neutralization Tests ; Plasmids ; SARS-CoV-2/physiology ; Transfection ; Virus Internalization
Czasopismo naukowe
Tytuł :
Phillyrin (KD-1) exerts anti-viral and anti-inflammatory activities against novel coronavirus (SARS-CoV-2) and human coronavirus 229E (HCoV-229E) by suppressing the nuclear factor kappa B (NF-κB) signaling pathway.
Autorzy :
Ma Q; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Li R; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Pan W; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Huang W; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Liu B; Kunming University of Science and Technology Library, Kunming, China.
Xie Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Wang Z; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Li C; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Jiang H; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Huang J; Technology Centre, Guangzhou Customs, Guangzhou, China.
Shi Y; Technology Centre, Guangzhou Customs, Guangzhou, China.
Dai J; Technology Centre, Guangzhou Customs, Guangzhou, China.
Zheng K; Technology Centre, Guangzhou Customs, Guangzhou, China.
Li X; Technology Centre, Guangzhou Customs, Guangzhou, China.
Hui M; Jilin Yatai Chinese Medicine Development Institute, Changchun, Jilin, China.
Fu L; Jilin Yatai Chinese Medicine Development Institute, Changchun, Jilin, China.
Yang Z; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China; State Key Laboratory of Quality Research in Chinese Medicine, Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology, Taipa, Macau SAR, China; KingMed Virology Diagnostic & Translational Center, Guangzhou, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2020 Nov; Vol. 78, pp. 153296. Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Journal Article
MeSH Terms :
Coronavirus Infections*/metabolism
Coronavirus Infections*/virology
Pandemics*
Pneumonia, Viral*/metabolism
Pneumonia, Viral*/virology
Anti-Inflammatory Agents/*pharmacology
Antiviral Agents/*pharmacology
Betacoronavirus/*drug effects
Coronavirus 229E, Human/*drug effects
Glucosides/*pharmacology
NF-kappa B/*metabolism
Animals ; COVID-19 ; Chlorocebus aethiops ; Coronavirus/drug effects ; Cytokines/metabolism ; Forsythia/chemistry ; Humans ; Phytotherapy ; Plant Extracts/pharmacology ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome/virology ; Signal Transduction/drug effects ; Vero Cells ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
Developing a Paper-Based Antigen Assay to Differentiate between Coronaviruses and SARS-CoV-2 Spike Variants.
Autorzy :
Hristov D; Department of Engineering, University of Massachusetts Boston, Boston, Massachusetts 02125, United States.
Rijal H; Department of Chemistry, University of Massachusetts Boston, Boston, Massachusetts 02125, United States.
Gomez-Marquez J; Little Devices Lab, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.
Hamad-Schifferli K; Department of Engineering, University of Massachusetts Boston, Boston, Massachusetts 02125, United States.; School for the Environment, University of Massachusetts Boston, Boston, Massachusetts 02125, United States.
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Źródło :
Analytical chemistry [Anal Chem] 2021 Jun 08; Vol. 93 (22), pp. 7825-7832. Date of Electronic Publication: 2021 May 26.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*
Coronavirus OC43, Human*
China ; Humans ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus
Czasopismo naukowe
Tytuł :
Development and Application of Human Coronavirus Protein Microarray for Specificity Analysis.
Autorzy :
Du PX; Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan 701, Taiwan, ROC.
Chou YY; Department of Nursing, Kaohsiung Armed Forces General Hospital, Kaohsiung 802, Taiwan, ROC.
Santos HM; Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan 701, Taiwan, ROC.
Keskin BB; Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan 701, Taiwan, ROC.
Hsieh MH; Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan, ROC.
Ho TS; Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan, ROC.; Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan 701, Taiwan, ROC.
Wang JY; Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan, ROC.; Center for Allergy and Clinical Immunology Research (ACIR), College of Medicine, National Cheng Kung University, Tainan 701, Taiwan, ROC.
Lin YL; Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan, ROC.
Syu GD; Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan 701, Taiwan, ROC.; International Center for Wound Repair and Regeneration, National Cheng Kung University, Tainan 701, Taiwan, ROC.; Research Center of Excellence in Regenerative Medicine, National Cheng Kung University, Tainan 701, Taiwan, ROC.
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Źródło :
Analytical chemistry [Anal Chem] 2021 Jun 01; Vol. 93 (21), pp. 7690-7698. Date of Electronic Publication: 2021 May 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*
Coronavirus OC43, Human*
Humans ; Protein Array Analysis ; Reproducibility of Results ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus
Czasopismo naukowe
Tytuł :
CoV-AbDab: the coronavirus antibody database.
Autorzy :
Raybould MIJ; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford OX1 3LB, UK.
Kovaltsuk A; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford OX1 3LB, UK.
Marks C; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford OX1 3LB, UK.
Deane CM; Oxford Protein Informatics Group, Department of Statistics, University of Oxford, Oxford OX1 3LB, UK.
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Źródło :
Bioinformatics (Oxford, England) [Bioinformatics] 2021 May 05; Vol. 37 (5), pp. 734-735.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*
Middle East Respiratory Syndrome Coronavirus*
Antibodies, Neutralizing ; Antibodies, Viral ; Humans ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus
Czasopismo naukowe
Tytuł :
Overinterpretation of the antiviral results for human coronavirus strain 229E (HCoV-229E) relative to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Autorzy :
Shewale JG; Rowpar Pharmaceuticals, Inc., Scottsdale, Arizona, USA.
Ratcliff JL; Rowpar Pharmaceuticals, Inc., Scottsdale, Arizona, USA.
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Źródło :
Journal of medical virology [J Med Virol] 2021 Apr; Vol. 93 (4), pp. 1900-1902. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Letter; Comment
MeSH Terms :
Antiviral Agents*/pharmacology
COVID-19*
Coronavirus 229E, Human*
Humans ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus
Opinia redakcyjna
Tytuł :
Prior infection by seasonal coronaviruses, as assessed by serology, does not prevent SARS-CoV-2 infection and disease in children, France, April to June 2020.
Autorzy :
Sermet-Gaudelus I; These authors contributed equally to the work.; Université de Paris, Paris, France.; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.; Institut Necker Enfants Malades, INSERM U 1171, Paris, France.
Temmam S; Pathogen Discovery Laboratory, Department of Virology, Institut Pasteur, Paris, France.; These authors contributed equally to the work.
Huon C; Pathogen Discovery Laboratory, Department of Virology, Institut Pasteur, Paris, France.
Behillil S; National Reference Center for Respiratory Viruses, Institut Pasteur, Paris, France.; Molecular Genetics of RNA Viruses, Department of Virology, CNRS UMR3569, Université de Paris, Institut Pasteur, Paris, France.
Gajdos V; Centre for Research in Epidemiology and Population Health, INSERM UMR1018, Villejuif, France.; Hôpital Antoine Beclere, Clamart, France.
Bigot T; Hub de Bioinformatique et Biostatistique - Département Biologie Computationnelle, Institut Pasteur, USR 3756 CNRS, Paris, France.; Pathogen Discovery Laboratory, Department of Virology, Institut Pasteur, Paris, France.
Lurier T; Université de Lyon, INRAE, VetAgro Sup, Usc 1233 UR RS2GP, Marcy l'Etoile, France.; Université de Lyon, INRAE, VetAgro Sup, UMR EPIA, Marcy l'Etoile, France.; Université Clermont Auvergne, INRAE, VetAgro Sup, UMR EPIA, Saint-Genès-Champanelle, France.
Chrétien D; Pathogen Discovery Laboratory, Department of Virology, Institut Pasteur, Paris, France.
Backovic M; Unité de Virologie Structurale, Institut Pasteur, Département de Virologie, CNRS, UMR3569, Paris, France.
Delaunay-Moisan A; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Donati F; National Reference Center for Respiratory Viruses, Institut Pasteur, Paris, France.; Molecular Genetics of RNA Viruses, Department of Virology, CNRS UMR3569, Université de Paris, Institut Pasteur, Paris, France.
Albert M; National Reference Center for Respiratory Viruses, Institut Pasteur, Paris, France.; Molecular Genetics of RNA Viruses, Department of Virology, CNRS UMR3569, Université de Paris, Institut Pasteur, Paris, France.
Foucaud E; Hôpital Jean Verdier, Bondy, France.
Mesplées B; Hôpital Louis Mourier, Colombes, France.
Benoist G; Hôpital Ambroise Paré, Boulogne Billancourt, France.
Faye A; Hôpital Robert Debré, Paris, France.
Duval-Arnould M; Hôpital Kremlin Bicêtre, Le Kremlin-Bicêtre, France.
Cretolle C; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Charbit M; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Aubart M; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Auriau J; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Lorrot M; Hôpital Armand Trousseau, Paris, France.
Kariyawasam D; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Fertitta L; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Orliaguet G; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Pigneur B; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Bader-Meunier B; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Briand C; Hôpital Louis Mourier, Colombes, France.
Enouf V; Plateforme de microbiologie mutualisée (P2M), Pasteur International Bioresources Network (PIBnet), Institut Pasteur, Paris, France.; National Reference Center for Respiratory Viruses, Institut Pasteur, Paris, France.; Molecular Genetics of RNA Viruses, Department of Virology, CNRS UMR3569, Université de Paris, Institut Pasteur, Paris, France.
Toubiana J; Unité Biodiversité et Epidemiologie des Bacteries Pathogènes, Institut Pasteur, Paris, France.; Université de Paris, Paris, France.; Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Paris, France.
Guilleminot T; Laboratoire de Microbiologie, Hôpital Necker-Enfants Malades, Paris, France.
van der Werf S; National Reference Center for Respiratory Viruses, Institut Pasteur, Paris, France.; Molecular Genetics of RNA Viruses, Department of Virology, CNRS UMR3569, Université de Paris, Institut Pasteur, Paris, France.
Leruez-Ville M; Laboratoire de Microbiologie, Hôpital Necker-Enfants Malades, Paris, France.
Eloit M; Ecole Nationale Vétérinaire d'Alfort, Maisons Alfort, France.; Pathogen Discovery Laboratory, Department of Virology, Institut Pasteur, Paris, France.
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Źródło :
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2021 Apr; Vol. 26 (13).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus OC43, Human*
Systemic Inflammatory Response Syndrome*
Antibodies, Viral/*immunology
COVID-19/*immunology
SARS-CoV-2/*immunology
Adolescent ; Antibodies, Viral/blood ; COVID-19/blood ; COVID-19/diagnosis ; Child ; Child, Preschool ; Cross-Sectional Studies ; Female ; France/epidemiology ; Humans ; Infant ; Infant, Newborn ; Male ; Paris ; Seasons ; Serologic Tests/methods ; Spike Glycoprotein, Coronavirus
SCR Disease Name :
pediatric multisystem inflammatory disease, COVID-19 related
Czasopismo naukowe

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